ATE312913T1 - Klasse e-spannungsabh ngiger calciumkanale- antagonist und verfahren - Google Patents

Klasse e-spannungsabh ngiger calciumkanale- antagonist und verfahren

Info

Publication number
ATE312913T1
ATE312913T1 AT97938097T AT97938097T ATE312913T1 AT E312913 T1 ATE312913 T1 AT E312913T1 AT 97938097 T AT97938097 T AT 97938097T AT 97938097 T AT97938097 T AT 97938097T AT E312913 T1 ATE312913 T1 AT E312913T1
Authority
AT
Austria
Prior art keywords
class
peptides
calcium channel
voltage dependent
channel antagonist
Prior art date
Application number
AT97938097T
Other languages
English (en)
Inventor
Robert Newcomb
Andrew L Palma
Balazs G Szoke
Katalin Tarczy-Hornoch
William F Hopkins
Ruth L Cong
George P Miljanich
Robin Dean
Laszlo Nadasdi
Laslo Urge
Stephen Scott Bowersox
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Application granted granted Critical
Publication of ATE312913T1 publication Critical patent/ATE312913T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds
    • Y10S530/858—Proteins from animals other than mammals or birds insects; venom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97938097T 1996-08-02 1997-08-01 Klasse e-spannungsabh ngiger calciumkanale- antagonist und verfahren ATE312913T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2297896P 1996-08-02 1996-08-02
PCT/US1997/013600 WO1998005780A2 (en) 1996-08-02 1997-08-01 Voltage-gated calcium channel antagonist and methods

Publications (1)

Publication Number Publication Date
ATE312913T1 true ATE312913T1 (de) 2005-12-15

Family

ID=21812432

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97938097T ATE312913T1 (de) 1996-08-02 1997-08-01 Klasse e-spannungsabh ngiger calciumkanale- antagonist und verfahren

Country Status (9)

Country Link
US (2) US6156726A (de)
EP (1) EP0920504B1 (de)
JP (2) JP2001514482A (de)
CN (1) CN1226929A (de)
AT (1) ATE312913T1 (de)
AU (1) AU734576B2 (de)
CA (1) CA2262753A1 (de)
DE (1) DE69734885T2 (de)
WO (1) WO1998005780A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489119B1 (en) * 1996-03-29 2002-12-03 Elan Pharmaceuticals, Inc. Analgesic screening method and composition
GB2341318A (en) * 1998-09-14 2000-03-15 Boehringer Ingelheim Pharma A Dihydroisoquinoline (LOE 908) and Traumatic Brain Injury.
JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
CN1133461C (zh) 2000-04-11 2004-01-07 厦门北大之路生物工程有限公司 虎纹捕鸟蜘蛛毒素提取物在制备镇痛药物中的应用
US20040254134A1 (en) * 2001-04-27 2004-12-16 Eduardo Marban Biological pacemaker
US20090175790A1 (en) * 2000-09-06 2009-07-09 The Johns Hopkins University Cardiac arrhythmia treatment methods and biological pacemaker
WO2002019966A2 (en) * 2000-09-06 2002-03-14 Johns Hopkins University Cardiac arrhythmia treatment methods
US8955619B2 (en) * 2002-05-28 2015-02-17 Weatherford/Lamb, Inc. Managed pressure drilling
JP2006508073A (ja) * 2002-10-02 2006-03-09 ザ・ジョンズ・ホプキンス・ユニバーシティー 限局的カルシウムチャネル調節方法
GB0225379D0 (en) * 2002-10-31 2002-12-11 Pfizer Ltd Therapeutic proline derivatives
US9701737B2 (en) 2003-02-19 2017-07-11 Camas, Incorporated Immunogen adherence and method of making and using same
US7829527B2 (en) * 2005-02-02 2010-11-09 University Of Vermont And State Agricultural College Emergence of a R-type Ca2+ channel (Cav 2.3) contributes to cerebral artery constriction following subarachnoid hemorrhage
AU2006304331A1 (en) * 2005-10-14 2007-04-26 The Johns Hopkins University Biologically excitable cells
US7836973B2 (en) 2005-10-20 2010-11-23 Weatherford/Lamb, Inc. Annulus pressure control drilling systems and methods
JP5019442B2 (ja) * 2007-04-26 2012-09-05 独立行政法人産業技術総合研究所 心筋の収縮を抑制するグラモストラ・スパチュラタ由来のポリペプチドおよびその遺伝子。
CA2798151A1 (en) * 2010-05-07 2011-11-10 Camas Incorporated Immunogen adherence and method of making and using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2146367C (en) * 1992-10-30 1999-07-20 Paul R. Kelbaugh Calcium channel blocking polypeptides from heteropoda venatoria
JP3534411B2 (ja) * 1993-07-30 2004-06-07 エラン ファーマシューティカルズ， インコーポレイテッド ヒトカルシウムチャネルα−１ＥサブユニットをコードするＤＮＡ

Also Published As

Publication number Publication date
JP2001514482A (ja) 2001-09-11
WO1998005780A3 (en) 1998-07-09
EP0920504A2 (de) 1999-06-09
CA2262753A1 (en) 1998-02-12
WO1998005780A2 (en) 1998-02-12
EP0920504B1 (de) 2005-12-14
AU734576B2 (en) 2001-06-14
CN1226929A (zh) 1999-08-25
JP2006051033A (ja) 2006-02-23
DE69734885T2 (de) 2006-08-24
AU4050397A (en) 1998-02-25
US6156726A (en) 2000-12-05
DE69734885D1 (de) 2006-01-19
US6653460B1 (en) 2003-11-25

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