ATE310102T1 - Dna-sequenzierung mit hoher auflösung mittels einem medium geringer viskosität - Google Patents

Dna-sequenzierung mit hoher auflösung mittels einem medium geringer viskosität

Info

Publication number
ATE310102T1
ATE310102T1 AT94907197T AT94907197T ATE310102T1 AT E310102 T1 ATE310102 T1 AT E310102T1 AT 94907197 T AT94907197 T AT 94907197T AT 94907197 T AT94907197 T AT 94907197T AT E310102 T1 ATE310102 T1 AT E310102T1
Authority
AT
Austria
Prior art keywords
dna sequencing
high resolution
low viscosity
solution
viscosity medium
Prior art date
Application number
AT94907197T
Other languages
English (en)
Inventor
Paul D Grossman
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE310102T1 publication Critical patent/ATE310102T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT94907197T 1993-01-21 1994-01-12 Dna-sequenzierung mit hoher auflösung mittels einem medium geringer viskosität ATE310102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/003,968 US5374527A (en) 1993-01-21 1993-01-21 High resolution DNA sequencing method using low viscosity medium
PCT/US1994/000394 WO1994017207A1 (en) 1993-01-21 1994-01-12 High resolution dna sequencing method using low viscosity medium

Publications (1)

Publication Number Publication Date
ATE310102T1 true ATE310102T1 (de) 2005-12-15

Family

ID=21708454

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94907197T ATE310102T1 (de) 1993-01-21 1994-01-12 Dna-sequenzierung mit hoher auflösung mittels einem medium geringer viskosität

Country Status (8)

Country Link
US (1) US5374527A (de)
EP (1) EP0680516B1 (de)
JP (3) JPH08509596A (de)
AT (1) ATE310102T1 (de)
AU (1) AU674390B2 (de)
CA (1) CA2153991C (de)
DE (1) DE69434542T2 (de)
WO (1) WO1994017207A1 (de)

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US6309829B1 (en) 1997-05-27 2001-10-30 Pe Corporation (Ny) Length determination of nucleic acid repeat sequences by discontinuous primer extension
US6008379A (en) 1997-10-01 1999-12-28 The Perkin-Elmer Corporation Aromatic-substituted xanthene dyes
US5958694A (en) 1997-10-16 1999-09-28 Caliper Technologies Corp. Apparatus and methods for sequencing nucleic acids in microfluidic systems
US5936087A (en) 1997-11-25 1999-08-10 The Perkin-Elmer Corporation Dibenzorhodamine dyes
US5948227A (en) * 1997-12-17 1999-09-07 Caliper Technologies Corp. Methods and systems for performing electrophoretic molecular separations
EP1072006A1 (de) * 1998-04-16 2001-01-31 Northeastern University Expert-system zur analyse von dna-sequenzierten elektropherogrammen
US6096875A (en) 1998-05-29 2000-08-01 The Perlein-Elmer Corporation Nucleotide compounds including a rigid linker
SE9802558D0 (sv) 1998-07-16 1998-07-16 Hanning Instr Ab Device for detection of fluorescent
US6263286B1 (en) * 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
JP2002525072A (ja) * 1998-09-16 2002-08-13 グラクソ グループ リミテッド 多重シーケンス法
WO2000046594A1 (en) * 1999-02-02 2000-08-10 Caliper Technologies Corp. Methods, devices and systems for characterizing proteins
US6716948B1 (en) 1999-07-31 2004-04-06 Symyx Technologies, Inc. Controlled-architecture polymers and use thereof as separation media
US6696022B1 (en) 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US6741983B1 (en) * 1999-09-28 2004-05-25 John D. Birdwell Method of indexed storage and retrieval of multidimensional information
US6807490B1 (en) * 2000-02-15 2004-10-19 Mark W. Perlin Method for DNA mixture analysis
US7255999B2 (en) 2001-05-21 2007-08-14 Monogram Biosciences, Inc. Methods and compositions for analyzing proteins
EP1305615B1 (de) * 2000-07-21 2004-09-29 Aclara BioSciences, Inc. Verfahren und vorrichtungen zur kapillarelektrophorese mit einer norbornenhaltigen oberflächenbeschichtung
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6582577B1 (en) 2000-08-31 2003-06-24 Visible Genetics Inc. Electrophoresis gel cassette
US6706162B1 (en) * 2000-09-25 2004-03-16 Applera Corporation High speed, high resolution compositions, methods, and kits for capillary electrophoresis
AU2002213125B2 (en) * 2000-10-11 2007-11-22 Applied Biosystems, Llc. Fluorescent nucleobase conjugates having anionic linkers
US6797139B2 (en) 2001-03-19 2004-09-28 Applera Corporation Detection cell for guiding excitation light therein and method for using same
US6596140B2 (en) * 2001-05-01 2003-07-22 Applera Corporation Multi-channel capillary electrophoresis device and method
US6902657B2 (en) * 2001-06-15 2005-06-07 Amersham Biosciences Corp. Electrophoresis separation media and methods
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
US7381317B2 (en) * 2002-08-12 2008-06-03 Beckman Coulter, Inc. Methods and compositions for capillary electrophoresis (CE)
US7162372B2 (en) * 2002-10-08 2007-01-09 Tse-Wei Wang Least-square deconvolution (LSD): a method to resolve DNA mixtures
US6833919B2 (en) * 2002-10-11 2004-12-21 Combisep Multiplexed, absorbance-based capillary electrophoresis system and method
US7179357B2 (en) * 2002-10-25 2007-02-20 Beckman Coulter, Inc. Serial sample injection in capillary electrophoresis
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WO2006081426A2 (en) * 2005-01-28 2006-08-03 Applera Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target dna template
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US20070014699A1 (en) 2005-06-23 2007-01-18 Beckman Coulter, Inc, Methods and apparatus for improving the sensitivity of capillary zone electrophoresis
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US7624087B2 (en) * 2006-11-16 2009-11-24 University Of Tennessee Research Foundation Method of expert system analysis of DNA electrophoresis data
US7664719B2 (en) * 2006-11-16 2010-02-16 University Of Tennessee Research Foundation Interaction method with an expert system that utilizes stutter peak rule
US7640223B2 (en) * 2006-11-16 2009-12-29 University Of Tennessee Research Foundation Method of organizing and presenting data in a table using stutter peak rule
US20080145898A1 (en) * 2006-12-14 2008-06-19 Applera Corporation Sequencing methods
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
US8235903B2 (en) * 2007-10-12 2012-08-07 Innoscion, Llc Remotely controlled implantable transducer and associated displays and controls
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US8846331B2 (en) 2010-08-27 2014-09-30 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
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US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
US10344326B2 (en) 2016-05-25 2019-07-09 International Business Machines Corporation Magnetic flux density based DNA sequencing
MA45491A (fr) 2016-06-27 2019-05-01 Juno Therapeutics Inc Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
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US5126021A (en) * 1991-07-17 1992-06-30 Applied Biosystems Inc. Low-viscosity polymer solution for capillary electrophoresis

Also Published As

Publication number Publication date
AU674390B2 (en) 1996-12-19
EP0680516A1 (de) 1995-11-08
JPH08509596A (ja) 1996-10-15
AU6087094A (en) 1994-08-15
CA2153991C (en) 2001-09-04
US5374527A (en) 1994-12-20
CA2153991A1 (en) 1994-08-04
DE69434542D1 (de) 2005-12-22
DE69434542T2 (de) 2006-08-10
EP0680516B1 (de) 2005-11-16
JP2002176976A (ja) 2002-06-25
WO1994017207A1 (en) 1994-08-04
JP2004000227A (ja) 2004-01-08

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