ATE308570T1 - Hydrogele - Google Patents

Hydrogele

Info

Publication number
ATE308570T1
ATE308570T1 AT01915126T AT01915126T ATE308570T1 AT E308570 T1 ATE308570 T1 AT E308570T1 AT 01915126 T AT01915126 T AT 01915126T AT 01915126 T AT01915126 T AT 01915126T AT E308570 T1 ATE308570 T1 AT E308570T1
Authority
AT
Austria
Prior art keywords
manufacture
composition
temperature
porogen
prostheses
Prior art date
Application number
AT01915126T
Other languages
English (en)
Inventor
Angelika Maria Domschke
Vimala Mary Francis
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE308570T1 publication Critical patent/ATE308570T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/04Polymerisation in solution
    • C08F2/06Organic solvent
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/44Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00Foams characterised by the foaming process
    • C08J2201/04Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/046Elimination of a polymeric phase
    • C08J2201/0462Elimination of a polymeric phase using organic solvents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00Characterised by the use of unspecified polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Polymerisation Methods In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
AT01915126T 2000-01-05 2001-01-03 Hydrogele ATE308570T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17446000P 2000-01-05 2000-01-05
PCT/EP2001/000024 WO2001049240A2 (en) 2000-01-05 2001-01-03 Hydrogels

Publications (1)

Publication Number Publication Date
ATE308570T1 true ATE308570T1 (de) 2005-11-15

Family

ID=22636227

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01915126T ATE308570T1 (de) 2000-01-05 2001-01-03 Hydrogele

Country Status (9)

Country Link
US (2) US6653420B2 (de)
EP (1) EP1252196B1 (de)
JP (1) JP4907824B2 (de)
AT (1) ATE308570T1 (de)
AU (1) AU4232701A (de)
CA (1) CA2394653A1 (de)
DE (1) DE60114565T2 (de)
NO (1) NO20023230L (de)
WO (1) WO2001049240A2 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
WO2001049240A2 (en) * 2000-01-05 2001-07-12 Novartis Ag Hydrogels
AU7299301A (en) 2000-06-21 2002-01-02 Bioarray Solutions Ltd Multianalyte molecular analysis using application-specific random particle arrays
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7262063B2 (en) * 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
ES2712173T3 (es) 2001-10-15 2019-05-09 Bioarray Solutions Ltd Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
CA2478479A1 (en) 2002-03-07 2003-09-18 University Of Delaware Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phagebeta protein, or hydroxyurea
AU2003226688B2 (en) * 2002-03-22 2009-08-13 Kuros Biosurgery Ag Composition for hard tissue augmentation
US8282912B2 (en) * 2002-03-22 2012-10-09 Kuros Biosurgery, AG Compositions for tissue augmentation
GB0216333D0 (en) * 2002-07-13 2002-08-21 Univ Cranfield Substance - selective polymer membranes
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
US20070286546A1 (en) * 2003-03-11 2007-12-13 Jean-Francois Masson Surface Initiated Thin Polymeric Films for Chemical Sensors
GB0307011D0 (en) * 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CN1882699A (zh) 2003-09-22 2006-12-20 佰尔瑞溶液有限公司 带有多个能共价结合生物分子的官能基团的表面固定化多电解质
EP1692298A4 (de) 2003-10-28 2008-08-13 Bioarray Solutions Ltd Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
JP2007509629A (ja) 2003-10-29 2007-04-19 バイオアレイ ソリューションズ リミテッド 二本鎖dnaの切断による複合核酸分析
AU2005224997B2 (en) * 2004-03-22 2010-06-24 Agency For Science, Technology And Research Method for obtaining graded pore structure in scaffolds for tissues and bone, and scaffolds with graded pore structure for tissue and bone
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US7313829B1 (en) * 2004-10-29 2008-01-01 Payload Systems, Inc. Sealing device for body suit and sealing method using hydrogels
WO2006053031A2 (en) 2004-11-12 2006-05-18 Mayo Foundation For Medical Education And Research Photocrosslinkable poly(caprolactone fumarate)
JP5527968B2 (ja) 2005-04-29 2014-06-25 メイヨ フオンデーシヨン フオー メデイカル エジユケーシヨン アンド リサーチ ポリ(カプロラクトンフマレート)、ポリ(エチレングリコールフマレート)およびそれらのコポリマーに基づく親水性/疎水性ポリマーネットワーク
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
MY146558A (en) * 2005-08-09 2012-08-30 Coopervision Int Holding Co Lp Compositions and methods for producing silicone hydrogel contact lenses
US7709544B2 (en) 2005-10-25 2010-05-04 Massachusetts Institute Of Technology Microstructure synthesis by flow lithography and polymerization
WO2008005035A1 (en) * 2006-07-05 2008-01-10 Agency For Science, Technology And Research Porous polymeric articles
WO2008063758A2 (en) 2006-10-05 2008-05-29 Massachussetts Institute Of Technology Multifunctional encoded particles for high-throughput analysis
US8821899B2 (en) * 2007-03-12 2014-09-02 Board Of Regents, The University Of Texas System Method and process for the production of multi-coated recognitive and releasing systems
US8771713B2 (en) * 2007-03-12 2014-07-08 Board Of Regents, The University Of Texas System Method and process for the production of multi-coated recognitive and releasing systems
US9155703B2 (en) * 2007-03-12 2015-10-13 Board Of Regents, The University Of Texas System Method and process for the production of multi-coated recognitive and releasing systems
US8741316B2 (en) * 2007-03-12 2014-06-03 Board Of Regents, The University Of Texas System Highly porous, recognitive polymer systems
JP2010523243A (ja) * 2007-04-13 2010-07-15 クロス・バイオサージェリー・アクチェンゲゼルシャフト 高分子組織シーラント
EP2225325B1 (de) 2007-07-25 2011-06-01 Alcon, Inc. Werkstoffe mit hohem brechungsindex für ophthalmische vorrichtungen
WO2009061759A1 (en) * 2007-11-09 2009-05-14 3M Innovative Properties Company Porous polymeric resins
EP2247718B1 (de) 2008-01-30 2019-01-16 Asterias Biotherapeutics, Inc. Synthetische oberflächen zur kultivierung von herzmuskelzellen aus stammzellen
AU2009210837A1 (en) * 2008-01-30 2009-08-13 Geron Corporation Cell culture article and screening
CA2714010C (en) * 2008-01-30 2020-06-16 Corning Incorporated Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
JP5191375B2 (ja) * 2008-02-27 2013-05-08 旭化成ファインケム株式会社 ビニルスルホン酸重合体の製造方法
TW201000155A (en) * 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
EP2179751A1 (de) * 2008-10-21 2010-04-28 Stichting Dutch Polymer Institute Makroporöse Polymervernetzungsmaterialien, Verfahren zu ihrer Herstellung und Verwendung
EP2398577A2 (de) * 2009-02-19 2011-12-28 Bonner, Alex Garfield Poröses interpenetrierendes polymernetzwerk
GB2473814B (en) * 2009-09-16 2014-06-11 Spheritech Ltd Hollow particulate support
US20110189253A1 (en) * 2010-01-29 2011-08-04 Warsaw Orthopedic, Inc. Biomaterial composition and method
WO2011097619A2 (en) 2010-02-08 2011-08-11 Regents Of The University Of Minnesota Silica-based composite ocular device and methods
EP2576839B1 (de) 2010-06-07 2017-05-10 Firefly Bioworks, Inc. Nukleinsäurenachweis und -quantifizierung durch posthybridisierungs-kennzeichnung und universelle kodierung
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2639272A1 (de) * 2012-03-13 2013-09-18 Cytec Surface Specialties, S.A. Durch Aktivenergiestrahlen härtende wässrige Emulsionen
US9974646B2 (en) 2012-09-05 2018-05-22 University Of Miami Keratoprosthesis, and system and method of corneal repair using same
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
EP2931327B1 (de) 2012-12-11 2019-02-13 Board Of Regents, The University Of Texas System Hydrogelmembran zur anhaftungsverhinderung
RU2543895C2 (ru) * 2013-05-17 2015-03-10 Общество С Ограниченной Ответственностью "Научно-Производственный Центр "Амфион" Гидрогелевый материал на основе сшиваемого поливинилового спирта
US11155809B2 (en) 2014-06-24 2021-10-26 Bio-Rad Laboratories, Inc. Digital PCR barcoding
EP3402904B1 (de) 2016-01-12 2025-07-23 Bio-Rad Laboratories, Inc. Synthese von barcoding-sequenzen mithilfe von phasenverschiebungsblöcken und verwendungen davon
WO2017142879A1 (en) * 2016-02-16 2017-08-24 The Regents Of The University Of California Methods for immune system modulation with microporous annealed particle gels
WO2017165620A1 (en) 2016-03-24 2017-09-28 Bio-Rad Laboratories, Inc. Use of gel beads to control droplet dispersion
EP3555290B1 (de) 2016-12-19 2022-11-02 Bio-Rad Laboratories, Inc. Markierte dna mit erhaltener tröpfchenmarkierungskontinuität
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
EP3642363B1 (de) 2017-06-20 2025-12-24 Bio-Rad Laboratories, Inc. Mda mit bead-oligonukleotid
EP3704247B1 (de) 2017-11-02 2023-01-04 Bio-Rad Laboratories, Inc. Genomische analyse auf transposasebasis
US12209277B2 (en) 2018-01-31 2025-01-28 Bio-Rad Laboratories, Inc. Methods and compositions for deconvoluting partition barcodes
US11479816B2 (en) 2018-08-20 2022-10-25 Bio-Rad Laboratories, Inc. Nucleotide sequence generation by barcode bead-colocalization in partitions
US20210170072A1 (en) * 2019-12-05 2021-06-10 Cornell University Atmosphere-breathing refillable biphasic device for cell replacement therapy
CN114904058B (zh) * 2021-12-22 2024-04-16 广州锐澄医疗技术有限公司 一种规则多孔支架及其制备方法与其在人工角膜中的应用
KR102759485B1 (ko) * 2023-09-01 2025-01-23 주식회사 티이바이오스 성질이 다른 광학부 및 지지부의 계면 접착을 이용한 인공각막의 제조 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3068825A (en) * 1958-05-26 1962-12-18 Rca Corp Assembling device for electron tubes
JPS5025517B1 (de) * 1970-12-19 1975-08-23
JPS59195621A (ja) * 1983-04-22 1984-11-06 Toyo Contact Lens Co Ltd 軟質コンタクトレンズ
JPS62250040A (ja) * 1986-04-23 1987-10-30 Agency Of Ind Science & Technol アルギン酸多孔質成形体の製造方法
NL8701548A (nl) * 1987-07-01 1989-02-01 Tno Polymeer netwerk, werkwijze voor het bereiden daarvan alsmede, de toepassing daarvan voor het bekleden en/of impregneren of voor het vervaardigen van ooglenzen, alsmede gevormd voortbrengsel, geheel of ten dele bestaande uit een dergelijk polymeer netwerk.
US5856409A (en) * 1989-04-07 1999-01-05 Dow Corning Corporation Method of making hydrophobic copolymers hydrophilic
GB9318641D0 (en) * 1993-09-08 1993-10-27 Edko Trading Representation Compositions
US5663264A (en) * 1993-12-27 1997-09-02 Hitachi Chemical Company, Ltd. Transparent resin and plastic lens
DE4406624A1 (de) * 1994-03-01 1995-09-07 Roehm Gmbh Vernetzte wasserlösliche Polymerdispersionen
US5760100B1 (en) * 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
JP3645008B2 (ja) * 1995-07-24 2005-05-11 三洋化成工業株式会社 バインダー組成物
US5922249A (en) * 1995-12-08 1999-07-13 Novartis Ag Ophthalmic lens production process
US6132462A (en) * 1995-12-22 2000-10-17 Santen Pharmaceutical Co., Ltd. Copolymers formed from three components and intraocular lenses made thereof
US6060530A (en) * 1996-04-04 2000-05-09 Novartis Ag Process for manufacture of a porous polymer by use of a porogen
US6648733B2 (en) * 1997-04-04 2003-11-18 Rodel Holdings, Inc. Polishing pads and methods relating thereto
US6592764B1 (en) * 1997-12-09 2003-07-15 The Regents Of The University Of California Block copolymer processing for mesostructured inorganic oxide materials
WO2001049240A2 (en) * 2000-01-05 2001-07-12 Novartis Ag Hydrogels
US6255360B1 (en) * 2000-05-15 2001-07-03 Novartis Ag Process for the manufacture of moldings
US6673847B2 (en) * 2002-04-01 2004-01-06 Rohm And Haas Company Water immiscible porogen removal process

Also Published As

Publication number Publication date
US6653420B2 (en) 2003-11-25
WO2001049240A3 (en) 2001-12-20
CA2394653A1 (en) 2001-07-12
AU4232701A (en) 2001-07-16
US20020004573A1 (en) 2002-01-10
WO2001049240A2 (en) 2001-07-12
JP2003519250A (ja) 2003-06-17
EP1252196B1 (de) 2005-11-02
US6897271B1 (en) 2005-05-24
NO20023230D0 (no) 2002-07-03
NO20023230L (no) 2002-07-03
EP1252196A2 (de) 2002-10-30
JP4907824B2 (ja) 2012-04-04
DE60114565D1 (de) 2005-12-08
DE60114565T2 (de) 2006-07-27

Similar Documents

Publication Publication Date Title
ATE308570T1 (de) Hydrogele
DE69915114D1 (de) Vernetzte polymere und refraktionsvorrichtung aus diesen geformt
NO20011292D0 (no) Polymerer
AR009657A1 (es) Un polimero poroso hidratable, sus usos, procesos para producirlo, y un dispositivo oftalmico, tal como una lente de contacto, y una cornea artificialque comprenden a dicho polimero
EP2443483B1 (de) Mehrarmige makromonomere, polymerisches material und kontaktlinse damit
WO2014093751A3 (en) Amphiphilic siloxane-containing vinylic monomers and uses thereof
DE60139007D1 (de) Ophtalmische linsen und zusammensetzungen und verfahren zu deren herstellung
DK1246688T3 (da) Pasta, velegnet til silketryk, til fremstilling af en porös polymermembran til en biosensor
BR0316478A (pt) Estabilização de materiais poliméricos contendo poli(oxialquileno)
TW200500195A (en) Diluents for forming clear, wettable silicone hydrogel articles
WO2013177523A3 (en) Polymers and nanogel materials and methods for making and using the same
HK1208690A1 (en) Polymers and nanogel materials and methods for making and using the same
ATE418560T1 (de) Auf aromaten basierende silylmonomere mit hohem brechungsindex
JP2002537422A5 (de)
WO2002010231A3 (en) Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same
PT1386935E (pt) Hidrogeles que respondem a estimulos duplos e os respectivos processos de sintese
BR0014830A (pt) Homopolìmero ou copolìmero de polifosfonato, lente ótica ou oftálmica e métodos para prepará-los
WO2007019495A3 (en) Chemical vapor deposition of hydrogel films
DE60226768D1 (de) Monofunktionelle aromatische siloxan-makromonomere mit hohem brechungsindex
AU2831900A (en) Stereocomplex hydrogels
AR114601A1 (es) Composición de tinta para lentes de contacto cosméticas
EP1336628A4 (de) Polymer und dieses enthaltende okularlinse
ATE521656T1 (de) Hydrophile, arylsiloxy-haltige makromonomere und polymere mit hohem brechungsindex sowie ophthalmische vorrichtungen mit solchen polymeren
Chen et al. Novel pH, ion sensitive polyampholyte gels based on carboxymethyl chitosan and gelatin
JP2021524611A (ja) 超高dk材料

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties