ATE307333T1 - Chromatographische vorrichtung - Google Patents

Chromatographische vorrichtung

Info

Publication number
ATE307333T1
ATE307333T1 AT99914469T AT99914469T ATE307333T1 AT E307333 T1 ATE307333 T1 AT E307333T1 AT 99914469 T AT99914469 T AT 99914469T AT 99914469 T AT99914469 T AT 99914469T AT E307333 T1 ATE307333 T1 AT E307333T1
Authority
AT
Austria
Prior art keywords
porous
pores
components
component
chromatographic apparatus
Prior art date
Application number
AT99914469T
Other languages
English (en)
Inventor
Ales Podgornik
Milos Barut
Ales Strancar
Djuro Josic
Original Assignee
Bia Separations Doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SI9800058A external-priority patent/SI9800058A/sl
Priority claimed from SI9800201A external-priority patent/SI20011A/sl
Application filed by Bia Separations Doo filed Critical Bia Separations Doo
Application granted granted Critical
Publication of ATE307333T1 publication Critical patent/ATE307333T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28042—Shaped bodies; Monolithic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28088—Pore-size distribution
    • B01J20/28092—Bimodal, polymodal, different types of pores or different pore size distributions in different parts of the sorbent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28095—Shape or type of pores, voids, channels, ducts
    • B01J20/28097—Shape or type of pores, voids, channels, ducts being coated, filled or plugged with specific compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6069—Construction of the column body with compartments or bed substructure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/80—Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/82—Shaped bodies, e.g. monoliths, plugs, tubes, continuous beds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/525—Physical parameters structural properties surface properties, e.g. porosity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/528—Monolithic sorbent material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT99914469T 1998-02-27 1999-02-27 Chromatographische vorrichtung ATE307333T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI9800058A SI9800058A (sl) 1998-02-27 1998-02-27 Ohišje za porozne cevne module
SI9800201A SI20011A (sl) 1998-07-14 1998-07-14 Konstrukcija cevnega modula večjih volumnov
PCT/EP1999/001391 WO1999044053A2 (en) 1998-02-27 1999-02-27 Chromatographic device

Publications (1)

Publication Number Publication Date
ATE307333T1 true ATE307333T1 (de) 2005-11-15

Family

ID=26665267

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99914469T ATE307333T1 (de) 1998-02-27 1999-02-27 Chromatographische vorrichtung

Country Status (12)

Country Link
US (1) US6736973B1 (de)
EP (1) EP1058844B1 (de)
JP (1) JP4109418B2 (de)
AT (1) ATE307333T1 (de)
AU (1) AU3328199A (de)
CA (1) CA2322009C (de)
CZ (1) CZ302614B6 (de)
DE (1) DE69927792T2 (de)
DK (1) DK1058844T3 (de)
ES (1) ES2247791T3 (de)
RU (1) RU2232385C2 (de)
WO (1) WO1999044053A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7138518B1 (en) 1996-11-13 2006-11-21 Transgenomic, Inc. Liquid chromatographic separation of polynucleotides
DE10033532A1 (de) * 2000-07-11 2002-01-31 Robert Hoehne Verfahren zum Abdichten eines porösen Formkörpers und Halterung für einen solchen Formkörper
DE01970200T1 (de) * 2000-09-25 2004-04-15 Gl Sciences Inc. Verfahren und einrichtung zum sammeln und konzentrieren von proben
EP1321176A1 (de) * 2001-12-18 2003-06-25 Boehringer Ingelheim International GmbH Verfahren und Vorrichtung zur Isolierung und Reinigung eines bestimmten Polynukleotides in industriellem Umfang
SE0201623D0 (sv) 2002-05-30 2002-05-30 Amersham Biosciences Ab Macroporous cross-linked polymer particles
US6749749B2 (en) 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
DE102005031560B4 (de) * 2005-07-06 2007-05-16 Sartorius Gmbh Membranhalter für die Membranadsorberchromatographie
US7704388B2 (en) * 2006-01-31 2010-04-27 Luknova, Inc Reusable liquid chromatographic columns
EP2043776A4 (de) * 2006-05-29 2009-12-30 Ge Healthcare Bio Sciences Ab Herstellung von monolithischen gegenständen
JP4376919B2 (ja) * 2007-03-23 2009-12-02 株式会社日立ハイテクノロジーズ 分離カラム及びそれを用いた液体クロマトグラフ装置
JP4931006B2 (ja) * 2007-08-03 2012-05-16 オルガノ株式会社 モノリス状有機多孔質イオン交換体、その使用方法、製造方法及び製造に用いる鋳型
KR20140001257A (ko) 2008-05-13 2014-01-06 유니버시티 오브 캔사스 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법
US9302415B2 (en) 2008-05-22 2016-04-05 Proxeon Biosystems A/S Pre-assembled separation columns
WO2012015908A2 (en) * 2010-07-30 2012-02-02 Millipore Corporation Chromatography media and method
US20150030565A1 (en) 2012-01-09 2015-01-29 Sanofi Pasteur Biologics, Llc Purification of flaviviruses
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CA2897798A1 (en) * 2013-01-31 2014-08-07 Emd Millipore Corporation Chromatography media and method
WO2015195178A2 (en) * 2014-03-27 2015-12-23 Canon U.S. Life Sciences, Inc. Integration of ex situ fabricated porous polymer monoliths into fluidic chips
JP6652554B2 (ja) 2014-09-02 2020-02-26 イー・エム・デイー・ミリポア・コーポレイシヨン ナノフィブリル化表面特徴を有する高表面積繊維媒体
KR102162753B1 (ko) 2014-12-08 2020-10-07 이엠디 밀리포어 코포레이션 혼합층 이온 교환 흡착제
JP2016210705A (ja) 2015-04-30 2016-12-15 昭和電工株式会社 タンパク質凝集体の除去方法
WO2020094731A1 (en) 2018-11-06 2020-05-14 Arhel Projektiranje In Inzeniring D.O.O. Method for manufacturing highly purified lactoferrin and lactoperoxidase from milk, colostrum and acid or sweet whey

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3483990A (en) * 1967-03-06 1969-12-16 Beckman Instruments Inc Dialyzer apparatus
US4116836A (en) * 1977-03-01 1978-09-26 Henry Allen Chromatographic column
US4676898A (en) * 1985-11-04 1987-06-30 Sepragen Corporation Chromatography column using horizontal flow
US4627918A (en) * 1985-11-04 1986-12-09 Sepragen Corporation Chromatography column using horizontal flow
GB2201904B (en) 1987-02-14 1990-12-19 Domnick Hunter Filters Ltd Device for liquid chromatography or immobilised enzyme reaction
US5019270A (en) * 1989-07-06 1991-05-28 Perseptive Biosystems, Inc. Perfusive chromatography
DE4119203A1 (de) * 1990-08-07 1992-02-13 Bio Rad Laboratories Chromatographieeinsatz
GB9019855D0 (en) * 1990-09-11 1990-10-24 Pall Corp Depth filter media
US5316680A (en) * 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
WO1994009063A1 (en) * 1992-10-21 1994-04-28 Cornell Research Foundation, Inc. Pore-size selective modification of porous materials
ES2155528T3 (es) * 1994-08-23 2001-05-16 Bia Separations Doo Procedimiento y dispositivo para la rapida separacion y/o conversion de sustratos.
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5522994A (en) * 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths

Also Published As

Publication number Publication date
JP2002505428A (ja) 2002-02-19
RU2232385C2 (ru) 2004-07-10
WO1999044053A3 (en) 1999-10-07
ES2247791T3 (es) 2006-03-01
CA2322009A1 (en) 1999-09-02
DE69927792D1 (de) 2006-03-02
WO1999044053A2 (en) 1999-09-02
DK1058844T3 (da) 2006-03-06
EP1058844B1 (de) 2005-10-19
CA2322009C (en) 2009-09-22
US6736973B1 (en) 2004-05-18
EP1058844A2 (de) 2000-12-13
DE69927792T2 (de) 2006-07-20
AU3328199A (en) 1999-09-15
CZ20003135A3 (cs) 2001-01-17
CZ302614B6 (cs) 2011-08-03
JP4109418B2 (ja) 2008-07-02

Similar Documents

Publication Publication Date Title
ATE307333T1 (de) Chromatographische vorrichtung
BR9708355A (pt) Processo para produção de um polímero poroso através do uso de um porogénio
ES2174895T3 (es) Combinaciones metalicas complejas con contenido en carbenos heterociclicos.
DE69529956T2 (de) Poröse polytetrafluoräthylen-verbundmembran
ID24456A (id) Piringan optik, peralatan reproduksi dan metoda reproduksinya
TR199501678A2 (tr) Gelistirilmis sivi gecirgenligine sahip emici yapi.
DE69936675D1 (de) WDM System mit einem optischen Verstärker geeignet zum Umschalten zwischen AGC-, ALC- und Sicherheits-Betriebsmoden
KR970703291A (ko) 다공성 탄소재, 그 제조방법 및 그 용도
DE69907530D1 (de) Anorganisches poröses Material enthaltende Zusammensetzung, und Verfahren zu deren Herstellung
GB0207813D0 (en) Electrochemical detector systems
DK1095096T3 (da) Trådagtige porøse film og fremgangsmåde til fremstilling af disse
DK0918818T3 (da) Oxygenindfangende flerkomponentsammensætning
EP0663231A3 (de) Ionentransportmembrane mit einer porösen leitenden Katalysator enthaltenden Mischschicht.
DE69717322D1 (de) Hochdurchlässige zusammengesetzte Umkehrosmosemembran
DE60225803D1 (de) Poröse folie, faserverbundfolie und verfahren zu deren herstellung
NO20011321D0 (no) Porøse polymerpartikler
DE69938896D1 (de) Den gasen unter vorbeugung von kapillarer kondensation
FR2816847B1 (fr) Biomateriaux polymeriques poreux, procede de preparation et utilisations
DE69723349D1 (de) Vorrichtung zur Entnahme von schädlichen Flüssigkeitsproben, insbesondere mit Festteilchen beladene
DE69924085D1 (de) Hochdurchlässige, Komposit-Umkehrosmosemembran und Verfahren zu deren Herstellung
IS4925A (is) Flytjanlegt, öruggt aðgerðakerfi fyrir forritanlegan búnað
MXPA03000946A (es) Aparato y metodo para producir particulas porosas de polimero.
EA199800089A1 (ru) Газопроницаемый материал
DE69518397T2 (de) Elektronenstrahlquelle und Herstellungsverfahren derselben, Elektronenstrahlquellenvorrichtung und Elektronenstrahlgerät unter Verwendung derselben
ATE259445T1 (de) Trocknungsmedium zur gleichmässigen verteilung der trockenluft, vorrichtung zu dessen ausführung und dadurch erhaltene cellulosehaltigen faserstrukturen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1058844

Country of ref document: EP