ATE304886T1 - Oxazolidinones zur behandlung von augeninfektionen - Google Patents
Oxazolidinones zur behandlung von augeninfektionenInfo
- Publication number
- ATE304886T1 ATE304886T1 AT99933483T AT99933483T ATE304886T1 AT E304886 T1 ATE304886 T1 AT E304886T1 AT 99933483 T AT99933483 T AT 99933483T AT 99933483 T AT99933483 T AT 99933483T AT E304886 T1 ATE304886 T1 AT E304886T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- oxazolidinones
- eye infections
- oxazolidinone
- treating
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 208000001860 Eye Infections Diseases 0.000 title 1
- 208000011323 eye infectious disease Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9276598P | 1998-07-14 | 1998-07-14 | |
| PCT/US1999/012367 WO2000003710A1 (en) | 1998-07-14 | 1999-07-07 | Oxazolidinones to treat eye infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE304886T1 true ATE304886T1 (de) | 2005-10-15 |
Family
ID=22235050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99933483T ATE304886T1 (de) | 1998-07-14 | 1999-07-07 | Oxazolidinones zur behandlung von augeninfektionen |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US6337329B1 (https=) |
| EP (1) | EP1096934B1 (https=) |
| JP (1) | JP2002520359A (https=) |
| KR (1) | KR20010079530A (https=) |
| CN (1) | CN1305374A (https=) |
| AT (1) | ATE304886T1 (https=) |
| AU (1) | AU740781B2 (https=) |
| BG (1) | BG64666B1 (https=) |
| BR (1) | BR9912004A (https=) |
| CA (1) | CA2334811A1 (https=) |
| DE (1) | DE69927380T2 (https=) |
| DK (1) | DK1096934T3 (https=) |
| EA (1) | EA003274B1 (https=) |
| EE (1) | EE200100026A (https=) |
| ES (1) | ES2249020T3 (https=) |
| HU (1) | HUP0102836A3 (https=) |
| ID (1) | ID27276A (https=) |
| IL (1) | IL140769A0 (https=) |
| NO (1) | NO20010202L (https=) |
| NZ (1) | NZ509375A (https=) |
| PL (1) | PL345544A1 (https=) |
| PT (1) | PT1096934E (https=) |
| SG (1) | SG125079A1 (https=) |
| SK (1) | SK20332000A3 (https=) |
| TR (1) | TR200100066T2 (https=) |
| WO (1) | WO2000003710A1 (https=) |
| ZA (1) | ZA200100038B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR020660A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Composiciones antibioticas para el tratamiento de ojos, oidos y nariz |
| ATE337002T1 (de) * | 1999-09-13 | 2006-09-15 | Insite Vision Inc | Topische behandlung zur vorbeugung von augeninfektionen |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US6562820B2 (en) | 2000-07-05 | 2003-05-13 | Pharmacia & Upjohn Company | Method for treatment and prevention of mastitis |
| PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
| PE20020578A1 (es) * | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
| US7125568B2 (en) * | 2001-08-23 | 2006-10-24 | Sung Michael T | Lipophilic drug compositions |
| US20030069235A1 (en) * | 2001-09-14 | 2003-04-10 | J. Greg Slatter | Treatment for ocular infections |
| BR0307898A (pt) * | 2002-02-22 | 2004-12-07 | Pharmacia Corp | Formulações de droga antibiótica oftálmica contendo um composto de ciclodextrina e cloreto de cetil piridìnio |
| TW201043267A (en) * | 2009-03-19 | 2010-12-16 | Intervet Int Bv | In situ constituting a vaccine for administration to a predetermined herd of animals |
| CN101766628B (zh) * | 2010-01-20 | 2012-07-04 | 广东宏盈科技有限公司 | 一种眼科外用抗细菌感染药物 |
| CN105007910B (zh) | 2012-09-13 | 2019-03-19 | 星法马有限公司 | 眼部感染的治疗或预防药物的制造用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164510A (en) | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
| ATE146783T1 (de) * | 1991-11-01 | 1997-01-15 | Upjohn Co | Substituierte aryl- und heteroaryl- phenyloxazolidinone |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| EP0730591B1 (en) | 1993-11-22 | 1999-07-14 | PHARMACIA & UPJOHN COMPANY | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| DE4425612A1 (de) | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| CA2256543C (en) * | 1996-05-31 | 2010-12-07 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
-
1999
- 1999-07-07 CN CN99807427A patent/CN1305374A/zh active Pending
- 1999-07-07 JP JP2000559845A patent/JP2002520359A/ja not_active Withdrawn
- 1999-07-07 EE EEP200100026A patent/EE200100026A/xx unknown
- 1999-07-07 CA CA002334811A patent/CA2334811A1/en not_active Abandoned
- 1999-07-07 IL IL14076999A patent/IL140769A0/xx unknown
- 1999-07-07 DE DE69927380T patent/DE69927380T2/de not_active Expired - Fee Related
- 1999-07-07 PL PL99345544A patent/PL345544A1/xx unknown
- 1999-07-07 DK DK99933483T patent/DK1096934T3/da active
- 1999-07-07 ID IDW20002687A patent/ID27276A/id unknown
- 1999-07-07 PT PT99933483T patent/PT1096934E/pt unknown
- 1999-07-07 BR BR9912004-6A patent/BR9912004A/pt not_active Application Discontinuation
- 1999-07-07 WO PCT/US1999/012367 patent/WO2000003710A1/en not_active Ceased
- 1999-07-07 ES ES99933483T patent/ES2249020T3/es not_active Expired - Lifetime
- 1999-07-07 HU HU0102836A patent/HUP0102836A3/hu unknown
- 1999-07-07 EP EP99933483A patent/EP1096934B1/en not_active Expired - Lifetime
- 1999-07-07 SG SG200300091A patent/SG125079A1/en unknown
- 1999-07-07 KR KR1020017000567A patent/KR20010079530A/ko not_active Ceased
- 1999-07-07 EA EA200100133A patent/EA003274B1/ru unknown
- 1999-07-07 SK SK2033-2000A patent/SK20332000A3/sk unknown
- 1999-07-07 US US09/349,430 patent/US6337329B1/en not_active Expired - Fee Related
- 1999-07-07 AU AU49530/99A patent/AU740781B2/en not_active Ceased
- 1999-07-07 TR TR2001/00066T patent/TR200100066T2/xx unknown
- 1999-07-07 AT AT99933483T patent/ATE304886T1/de not_active IP Right Cessation
- 1999-07-07 NZ NZ509375A patent/NZ509375A/en unknown
-
2001
- 2001-01-02 ZA ZA200100038A patent/ZA200100038B/en unknown
- 2001-01-10 BG BG105142A patent/BG64666B1/bg unknown
- 2001-01-12 NO NO20010202A patent/NO20010202L/no not_active Application Discontinuation
- 2001-09-19 US US09/955,679 patent/US6740652B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1096934 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |