ATE301667T1 - Anthracyclinglykosid-14-sulfon säurederivate mit antitumorwirkung - Google Patents
Anthracyclinglykosid-14-sulfon säurederivate mit antitumorwirkungInfo
- Publication number
- ATE301667T1 ATE301667T1 AT02730284T AT02730284T ATE301667T1 AT E301667 T1 ATE301667 T1 AT E301667T1 AT 02730284 T AT02730284 T AT 02730284T AT 02730284 T AT02730284 T AT 02730284T AT E301667 T1 ATE301667 T1 AT E301667T1
- Authority
- AT
- Austria
- Prior art keywords
- anthracycling
- lycoside
- acid derivatives
- antitumor effect
- sulfone acid
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 229930190071 lycoside Natural products 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0114654.7A GB0114654D0 (en) | 2001-06-15 | 2001-06-15 | Anti-tumor compound |
| PCT/EP2002/005907 WO2002102817A1 (en) | 2001-06-15 | 2002-05-29 | Anti-tumour anthracycline glycoside 14-sulfonic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301667T1 true ATE301667T1 (de) | 2005-08-15 |
Family
ID=9916687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02730284T ATE301667T1 (de) | 2001-06-15 | 2002-05-29 | Anthracyclinglykosid-14-sulfon säurederivate mit antitumorwirkung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040147463A1 (de) |
| EP (1) | EP1395599B1 (de) |
| JP (1) | JP2004534079A (de) |
| AT (1) | ATE301667T1 (de) |
| CA (1) | CA2447624A1 (de) |
| DE (1) | DE60205484T2 (de) |
| ES (1) | ES2245734T3 (de) |
| GB (1) | GB0114654D0 (de) |
| WO (1) | WO2002102817A1 (de) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1518390A (en) * | 1976-03-30 | 1978-07-19 | Farmaceutici Italia | Doxorubicin thioesters |
| JPS57106694A (en) * | 1980-11-01 | 1982-07-02 | Erba Carlo Spa | Anthracycline glycoside |
| DE3200809C2 (de) * | 1981-01-21 | 1986-08-28 | Farmitalia Carlo Erba S.p.A., Mailand/Milano | 4'-Desoxy-3'-epi-daunorubicin und -doxorubicin, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| GB2169286A (en) * | 1985-01-05 | 1986-07-09 | Erba Farmitalia | 4'-Deoxy-4'-halodoxorubicin-14-esters |
| GB8614323D0 (en) * | 1986-06-12 | 1986-07-16 | Erba Farmitalia | Anthracyclines |
| US4973675A (en) * | 1989-04-13 | 1990-11-27 | University Of Tennessee Research Center | Hybrid nitrosoureidoanthracyclines having antitumor activity |
| GB9416007D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Anthracyclinone derivatives |
| GB9727546D0 (en) * | 1997-12-31 | 1998-03-18 | Pharmacia & Upjohn Spa | Anthracycline glycosides |
| WO2000026223A2 (en) * | 1998-11-02 | 2000-05-11 | Board Of Regents, The University Of Texas System | Methods and compositions for the manufacture of highly potent anthracycline-based antitumor agents |
| AU778910B2 (en) * | 1999-03-19 | 2004-12-23 | Houston Pharmaceuticals, Inc. | Methods and compositions for the manufacture of C-3' and C-4' anthracycline antibiotics |
| GB9916882D0 (en) * | 1999-07-19 | 1999-09-22 | Pharmacia & Upjohn Spa | Antitumor synergistic composition |
| GB9917012D0 (en) * | 1999-07-20 | 1999-09-22 | Pharmacia & Upjohn Spa | Combined preparations comprising antitumor agents |
-
2001
- 2001-06-15 GB GBGB0114654.7A patent/GB0114654D0/en not_active Ceased
-
2002
- 2002-05-29 US US10/476,737 patent/US20040147463A1/en not_active Abandoned
- 2002-05-29 DE DE60205484T patent/DE60205484T2/de not_active Expired - Fee Related
- 2002-05-29 ES ES02730284T patent/ES2245734T3/es not_active Expired - Lifetime
- 2002-05-29 JP JP2003506289A patent/JP2004534079A/ja not_active Withdrawn
- 2002-05-29 CA CA002447624A patent/CA2447624A1/en not_active Abandoned
- 2002-05-29 EP EP02730284A patent/EP1395599B1/de not_active Expired - Lifetime
- 2002-05-29 AT AT02730284T patent/ATE301667T1/de not_active IP Right Cessation
- 2002-05-29 WO PCT/EP2002/005907 patent/WO2002102817A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004534079A (ja) | 2004-11-11 |
| CA2447624A1 (en) | 2002-12-27 |
| DE60205484T2 (de) | 2006-05-24 |
| GB0114654D0 (en) | 2001-08-08 |
| ES2245734T3 (es) | 2006-01-16 |
| DE60205484D1 (en) | 2005-09-15 |
| WO2002102817A1 (en) | 2002-12-27 |
| EP1395599A1 (de) | 2004-03-10 |
| US20040147463A1 (en) | 2004-07-29 |
| EP1395599B1 (de) | 2005-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |