ATE300952T1 - Verfahren zur verabreichung von wirkstoffen in das zentrale nervensystem oder lymphsystem - Google Patents
Verfahren zur verabreichung von wirkstoffen in das zentrale nervensystem oder lymphsystemInfo
- Publication number
- ATE300952T1 ATE300952T1 AT00984018T AT00984018T ATE300952T1 AT E300952 T1 ATE300952 T1 AT E300952T1 AT 00984018 T AT00984018 T AT 00984018T AT 00984018 T AT00984018 T AT 00984018T AT E300952 T1 ATE300952 T1 AT E300952T1
- Authority
- AT
- Austria
- Prior art keywords
- central nervous
- nervous system
- administration
- active ingredients
- disorders
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 210000003169 central nervous system Anatomy 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 210000002751 lymph Anatomy 0.000 title 1
- 102000004127 Cytokines Human genes 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 2
- 102100026720 Interferon beta Human genes 0.000 abstract 2
- 108090000467 Interferon-beta Proteins 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000014644 Brain disease Diseases 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 102000015696 Interleukins Human genes 0.000 abstract 1
- 108010063738 Interleukins Proteins 0.000 abstract 1
- 208000021386 Sjogren Syndrome Diseases 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229960001388 interferon-beta Drugs 0.000 abstract 1
- 229940047124 interferons Drugs 0.000 abstract 1
- 229940047122 interleukins Drugs 0.000 abstract 1
- 210000004324 lymphatic system Anatomy 0.000 abstract 1
- 210000000196 olfactory nerve Anatomy 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 210000003901 trigeminal nerve Anatomy 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20070899P | 1999-12-09 | 1999-12-09 | |
| PCT/US2000/033220 WO2001041782A2 (en) | 1999-12-09 | 2000-12-08 | Method for administering a cytokine to the central nervous system and the lymphatic system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE300952T1 true ATE300952T1 (de) | 2005-08-15 |
Family
ID=22742853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00984018T ATE300952T1 (de) | 1999-12-09 | 2000-12-08 | Verfahren zur verabreichung von wirkstoffen in das zentrale nervensystem oder lymphsystem |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20010043915A1 (de) |
| EP (1) | EP1237567B1 (de) |
| JP (1) | JP2003516360A (de) |
| AT (1) | ATE300952T1 (de) |
| AU (1) | AU783208B2 (de) |
| CA (1) | CA2393688A1 (de) |
| DE (1) | DE60021760T2 (de) |
| IL (1) | IL150109A0 (de) |
| NO (1) | NO20022731L (de) |
| WO (1) | WO2001041782A2 (de) |
Families Citing this family (88)
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| US20060024270A1 (en) * | 2000-08-23 | 2006-02-02 | The New York Hospital Medical Center Of Queens | Compositions and methods for preventing or treating encephalitis with interferon |
| US6589591B1 (en) * | 2001-07-10 | 2003-07-08 | Baylor College Of Medicine | Method for treating medical devices using glycerol and an antimicrobial agent |
| US20030187381A1 (en) * | 2001-12-28 | 2003-10-02 | Genzyme Corporation | Bioresorbable foam packing device and use thereof |
| US7674453B2 (en) | 2002-02-06 | 2010-03-09 | Ares Trading Sa | Tumor necrosis factor combined with interferon in demyelinating diseases |
| US20070004743A1 (en) * | 2002-02-25 | 2007-01-04 | Xiao Linda L | Intranasal administration of mc4-r agonists |
| US20040037809A1 (en) * | 2002-06-28 | 2004-02-26 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of interferon beta |
| DE60332358D1 (de) * | 2002-09-09 | 2010-06-10 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
| US8524899B2 (en) | 2003-03-04 | 2013-09-03 | California Institute Of Technology | Alternative heterocycles for DNA recognition |
| CA2516990A1 (en) * | 2003-03-19 | 2004-09-30 | Ares Trading S.A. | Treatment of alzheimer's disease |
| FR2864901B1 (fr) * | 2004-01-09 | 2007-10-05 | Philippe Perovitch | Composition pour le traitement au contact des hyposialies, incluant de la pilocarpine et a effets multiples |
| WO2005071101A1 (en) * | 2004-01-23 | 2005-08-04 | University Hospital Of Basel | Treatment of hepatitis c infection by increasing stat1 methylation |
| US20070212306A1 (en) * | 2004-06-07 | 2007-09-13 | Quay Steven C | Intranasal formulations of interferon beta free of stabilizers that are proteins or polypeptides |
| US7776312B2 (en) * | 2004-08-13 | 2010-08-17 | Healthpartners Research Foundation | Method of treating Alzheimer's disease comprising administering deferoxamine (DFO) to the upper one-third of the nasal cavity |
| US9216161B2 (en) | 2004-08-13 | 2015-12-22 | Healthpartners Research Foundation | Methods of treating Huntington's disease comprising administering metal chelators to the upper one-third of the nasal cavity |
| US7618615B2 (en) | 2004-08-13 | 2009-11-17 | Healthpartners Research Foundation | Methods for providing neuroprotection for the animal central nervous system against neurodegeneration caused by ischemia |
| US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
| US8642564B2 (en) * | 2004-08-25 | 2014-02-04 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US20060046969A1 (en) * | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Antibacterial compositions for drug administration |
| US9114069B2 (en) * | 2004-08-25 | 2015-08-25 | Aegis Therapeutics, Llc | Antibacterial compositions for drug administration |
| US20060251619A1 (en) * | 2005-05-04 | 2006-11-09 | Gilles Borrelly | Modified interferon-gamma polypeptides and methods for using modified interferon-gamma polypeptides |
| CA2620364A1 (en) | 2005-08-26 | 2007-03-01 | David C. Yeomans | Methods for treatment of headaches by administration of oxytocin |
| WO2007110231A2 (en) * | 2006-03-28 | 2007-10-04 | Nautilus Biotech, S.A. | MODIFIED INTERFERON-β (IFN-β) POLYPEPTIDES |
| US7534595B2 (en) * | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| EP1915986A1 (de) * | 2006-10-23 | 2008-04-30 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Wachstumsfaktorhaltige Lipidformulierungen |
| US9707274B2 (en) | 2007-06-08 | 2017-07-18 | Healthpartners Research & Education | Methods for preventing and treating post-traumatic stress disorder (PTSD) |
| EP2152240A4 (de) * | 2007-06-08 | 2012-05-09 | Healthpartners Res Foundation | Pharmazeutische zusammensetzungen und verfahren für verstärktes abzielen therapeutischer verbindungen auf das zentralnervensystem |
| US8221358B2 (en) * | 2007-11-20 | 2012-07-17 | Warsaw Orthopedic, Inc. | Devices and methods for delivering drug depots to a site beneath the skin |
| RU2357743C1 (ru) * | 2008-02-01 | 2009-06-10 | Аркадий Александрович Каспаров | Средство для лечения, способ получения средства для лечения и способ лечения отека роговицы и других проявлений ранней буллезной кератопатии |
| ES2586032T3 (es) | 2008-03-28 | 2016-10-11 | Hale Biopharma Ventures, Llc | Administración de composiciones de benzodiazepinas |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
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| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| EP2310030A4 (de) | 2008-06-13 | 2013-08-14 | Wisconsin Alumni Res Found | Neue antivirale peptide gegen das influenzavirus |
| US9198965B2 (en) | 2008-06-13 | 2015-12-01 | Wisconsin Alumni Research Foundation | Peptide adjuvant for influenza vaccination |
| US20100106132A1 (en) * | 2008-10-29 | 2010-04-29 | Warsaw Orthopedic, Inc. | Drug cartridge for delivering a drug depot comprising superior and inferior covers |
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| US8609088B2 (en) | 2011-05-10 | 2013-12-17 | Regents Of The University Of Minnesota | Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases |
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| CA2912678C (en) | 2013-05-15 | 2023-10-10 | Regents Of The University Of Minnesota | Adeno-associated virus mediated gene transfer to the central nervous system |
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| WO2019060662A1 (en) | 2017-09-22 | 2019-03-28 | The Trustees Of The University Of Pennsylvania | GENE THERAPY FOR THE TREATMENT OF MUCOPOLYSACCHARIDOSE TYPE II |
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| US12171821B2 (en) | 2018-06-13 | 2024-12-24 | Wisconsin Alumni Research Foundation (Warf) | Toxoplasma gondii vaccine |
| CN113473967B (zh) | 2019-01-03 | 2022-09-09 | 英倍尔制药公司 | 经鼻药物递送装置 |
| JP2023532444A (ja) | 2020-06-23 | 2023-07-28 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド・ア・ボディ・コーポレイト | 呼吸器病原体を診断し、covid-19に関連する転帰を予測する方法 |
| DK4319803T3 (da) | 2021-04-08 | 2025-12-15 | Vaxthera Sas | Coronavirusvaccine omfattende et mosaikprotein |
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| WO2026018213A1 (en) | 2024-07-18 | 2026-01-22 | Vaxthera Sas | A broadly protective mosaic vaccine against highly pathogenic avian influenza viruses |
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| ATE156704T1 (de) * | 1989-12-05 | 1997-08-15 | Ramsey Foundation | Neurologische wirkstoffe zur nasalen verabreichung an das gehirn |
| US5624898A (en) * | 1989-12-05 | 1997-04-29 | Ramsey Foundation | Method for administering neurologic agents to the brain |
| US5215741A (en) | 1990-10-30 | 1993-06-01 | Amarillo Cell Culture Company, Incorporated | Method for prevention of parasite infections |
| US5676942A (en) | 1992-02-10 | 1997-10-14 | Interferon Sciences, Inc. | Composition containing human alpha interferon species proteins and method for use thereof |
| CA2094217A1 (en) * | 1992-04-17 | 1993-10-18 | Yasutaka Igari | Transmucosal therapeutic composition |
| ES2313714T3 (es) * | 1992-06-22 | 2009-03-01 | The Regents Of The University Of California | Antagonistas de receptores de glicina y uso de los mismos. |
| JPH0741428A (ja) | 1993-07-30 | 1995-02-10 | Teijin Ltd | ペプチド、蛋白質性薬物経鼻・経肺製剤 |
| US5514670A (en) * | 1993-08-13 | 1996-05-07 | Pharmos Corporation | Submicron emulsions for delivery of peptides |
| US5545723A (en) * | 1994-03-15 | 1996-08-13 | Biogen Inc. | Muteins of IFN-β |
| US5675942A (en) * | 1995-08-28 | 1997-10-14 | Crawford; Van | Wall panel alignment device and spacer |
| AU724689B2 (en) * | 1996-05-09 | 2000-09-28 | Pharma Pacific Pty Ltd | Method of treatment |
| HUP9602024A3 (en) * | 1996-07-25 | 1999-05-28 | Toth Sandor | Pharmaceutical composition containing aminoacid for external use |
| US6036949A (en) | 1998-03-05 | 2000-03-14 | Amarillo Biosciences, Inc. | Treatment of fibromyalgia with low doses of interferon |
| WO2000033814A2 (en) * | 1998-12-09 | 2000-06-15 | Chiron Corporation | Method for administering agents to the central nervous system |
| ES2173679T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
-
2000
- 2000-12-08 AT AT00984018T patent/ATE300952T1/de not_active IP Right Cessation
- 2000-12-08 CA CA002393688A patent/CA2393688A1/en not_active Abandoned
- 2000-12-08 WO PCT/US2000/033220 patent/WO2001041782A2/en not_active Ceased
- 2000-12-08 EP EP00984018A patent/EP1237567B1/de not_active Expired - Lifetime
- 2000-12-08 JP JP2001543126A patent/JP2003516360A/ja active Pending
- 2000-12-08 DE DE60021760T patent/DE60021760T2/de not_active Expired - Fee Related
- 2000-12-08 AU AU20698/01A patent/AU783208B2/en not_active Ceased
- 2000-12-08 US US09/733,168 patent/US20010043915A1/en not_active Abandoned
- 2000-12-08 IL IL15010900A patent/IL150109A0/xx unknown
-
2002
- 2002-03-20 US US10/102,163 patent/US6991785B2/en not_active Expired - Fee Related
- 2002-06-07 NO NO20022731A patent/NO20022731L/no not_active Application Discontinuation
-
2005
- 2005-09-09 US US11/222,669 patent/US20060159626A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU783208B2 (en) | 2005-10-06 |
| DE60021760D1 (de) | 2005-09-08 |
| IL150109A0 (en) | 2002-12-01 |
| US20060159626A1 (en) | 2006-07-20 |
| EP1237567A2 (de) | 2002-09-11 |
| US20010043915A1 (en) | 2001-11-22 |
| NO20022731D0 (no) | 2002-06-07 |
| DE60021760T2 (de) | 2006-06-08 |
| CA2393688A1 (en) | 2001-06-14 |
| NO20022731L (no) | 2002-08-08 |
| US6991785B2 (en) | 2006-01-31 |
| WO2001041782A3 (en) | 2002-01-17 |
| EP1237567B1 (de) | 2005-08-03 |
| JP2003516360A (ja) | 2003-05-13 |
| AU2069801A (en) | 2001-06-18 |
| US20020141971A1 (en) | 2002-10-03 |
| WO2001041782A2 (en) | 2001-06-14 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |