DE69928563D1 - Verabreichung von neurotropischen wirkstoffen in das zentrale nervensystem - Google Patents

Verabreichung von neurotropischen wirkstoffen in das zentrale nervensystem

Info

Publication number
DE69928563D1
DE69928563D1 DE69928563T DE69928563T DE69928563D1 DE 69928563 D1 DE69928563 D1 DE 69928563D1 DE 69928563 T DE69928563 T DE 69928563T DE 69928563 T DE69928563 T DE 69928563T DE 69928563 D1 DE69928563 D1 DE 69928563D1
Authority
DE
Germany
Prior art keywords
nervous system
central nervous
neurotropic
activities
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69928563T
Other languages
English (en)
Other versions
DE69928563T2 (de
Inventor
Ii Frey
Xuequing Chen
Robert Gary Thorne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69928563D1 publication Critical patent/DE69928563D1/de
Application granted granted Critical
Publication of DE69928563T2 publication Critical patent/DE69928563T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
DE69928563T 1998-12-09 1999-12-09 Abgeben von neurotropischen Wirkstoffen an das Zentralnervensystem Expired - Fee Related DE69928563T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20853898A 1998-12-09 1998-12-09
US208538 1998-12-09
PCT/US1999/029334 WO2000033813A1 (en) 1998-12-09 1999-12-09 Administration of neurotrophic agents to the central nervous system

Publications (2)

Publication Number Publication Date
DE69928563D1 true DE69928563D1 (de) 2005-12-29
DE69928563T2 DE69928563T2 (de) 2006-07-27

Family

ID=22774957

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69928563T Expired - Fee Related DE69928563T2 (de) 1998-12-09 1999-12-09 Abgeben von neurotropischen Wirkstoffen an das Zentralnervensystem

Country Status (7)

Country Link
EP (1) EP1137401B1 (de)
JP (1) JP2002531489A (de)
AT (1) ATE310501T1 (de)
AU (1) AU2049500A (de)
DE (1) DE69928563T2 (de)
ES (1) ES2252993T3 (de)
WO (1) WO2000033813A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003072056A2 (en) * 2002-02-25 2003-09-04 Chiron Corporation Intranasal administration of mc4-r agonists
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
EP1599474B1 (de) 2003-03-04 2013-04-24 California Institute Of Technology Heterocyclische oligomere Verbindungen zur DNS-Erkennung
WO2004105787A1 (en) * 2003-05-28 2004-12-09 The University Of Kyoto Methods of using combinations of egf-2 and egf-20 to treat central nervous system disorders
US20090136505A1 (en) 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
CA2598666A1 (en) * 2005-02-23 2006-08-31 Alza Corporation Intranasal administration of active agents to the central nervous system
EP1928484B1 (de) 2005-08-26 2010-02-24 The Board Of Trustees Of The Leland Stanford Junior University Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin
US8283160B2 (en) * 2007-09-11 2012-10-09 Frey Ii William H Methods, pharmaceutical compositions and articles of manufacture for administering therapeutic cells to the animal central nervous system
JP2011524373A (ja) 2008-06-13 2011-09-01 ウィスコンシン・アルムナイ・リサーチ・ファウンデーション インフルエンザウイルスに対する新規抗ウイルスペプチド
US9198965B2 (en) 2008-06-13 2015-12-01 Wisconsin Alumni Research Foundation Peptide adjuvant for influenza vaccination
CA2756206A1 (en) 2009-03-27 2010-09-30 Academia Sinica Methods and compositions for immunization against virus
US8718754B2 (en) 2009-05-19 2014-05-06 Eduard N. Lerner Device and methods for enhanced multi-delivery of biologically active substances into an organism and to prevent local irritation
US20120189581A1 (en) 2009-07-24 2012-07-26 Schultz-Cherry Stacey L Use of toxoplasma and derived compositions to prevent or treat microbial infections
US8609088B2 (en) 2011-05-10 2013-12-17 Regents Of The University Of Minnesota Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
WO2012174481A1 (en) 2011-06-15 2012-12-20 Nerve Access, Inc. Pharmaceutical compositions for intranasal administration for the treatment of neurodegenerative disorders
US20130280297A1 (en) 2012-04-11 2013-10-24 Lori Neal Use of toxoplasma gene products to prevent or treat microbial infections
KR101481741B1 (ko) * 2012-05-18 2015-01-13 전북대학교산학협력단 Ⅰgf­1을 이용한 변형 프리온 단백질에 의해 유도되는 세포자멸사의 억제방법
ES2442242B1 (es) * 2012-08-09 2014-11-25 Biotechnology Institute, I Mas D, S.L. Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación.
EP2916831A4 (de) * 2012-11-09 2016-07-13 3E Therapeutics Corp Röntgenkontrastmittelzusammensetzungen und verfahren zur verwendung davon zur behandlung von leiden im zusammenhang mit entzündungen
CN115120746A (zh) 2013-05-15 2022-09-30 明尼苏达大学董事会 腺相关病毒介导的基因向中枢神经系统转移
KR20180023884A (ko) 2015-01-07 2018-03-07 트라이제미나 인코퍼레이티드 마그네슘-함유 옥시토신 제제 및 사용 방법
WO2016130683A1 (en) * 2015-02-10 2016-08-18 University Of Washington Prolonged anti-diabetic effect of fibroblast growth factor 1 (fgf1)
WO2017085362A1 (en) * 2015-11-18 2017-05-26 Herantis Pharma Plc Compositions comprising cdnf or manf for use in the intranasal treatment of central nervous system diseases
JP7171439B2 (ja) 2016-04-15 2022-11-15 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア ムコ多糖症ii型を処置するための遺伝子療法
US11819539B2 (en) 2017-09-22 2023-11-21 The Trustees Of The University Of Pennsylvania Gene therapy for treating Mucopolysaccharidosis type II
WO2019241579A1 (en) 2018-06-13 2019-12-19 Wisconsin Alumni Research Foundation Toxoplasma gondii vaccine
WO2020078568A1 (en) 2018-10-19 2020-04-23 Humabs Biomed Sa Antibodies and methods for treatment of lyssavirus infection
JP7211603B2 (ja) * 2019-06-21 2023-01-24 学校法人日本大学 薬物送達用組成物および医薬組成物
WO2022215036A1 (en) 2021-04-08 2022-10-13 Vaxthera Sas Coronavirus vaccine comprising a mosaic protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001739A1 (en) * 1989-08-11 1991-02-21 Hahnemann University Dopaminergic neurotrophic factor for treatment of parkinson's disease
DE69031279T2 (de) * 1989-12-05 1998-03-19 Ramsey Foundation Neurologische wirkstoffe zur nasalen verabreichung an das gehirn
CA2174324A1 (en) * 1993-10-21 1995-04-27 Katsuya Mukae Pernasal composition and pernasal preparation containing the same
KR100568436B1 (ko) * 1996-02-27 2007-04-25 데이진 가부시키가이샤 분말상경비투여조성물

Also Published As

Publication number Publication date
EP1137401B1 (de) 2005-11-23
AU2049500A (en) 2000-06-26
DE69928563T2 (de) 2006-07-27
EP1137401A1 (de) 2001-10-04
JP2002531489A (ja) 2002-09-24
WO2000033813A1 (en) 2000-06-15
ATE310501T1 (de) 2005-12-15
ES2252993T3 (es) 2006-05-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

8339 Ceased/non-payment of the annual fee