ATE299873T1 - Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate - Google Patents

Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate

Info

Publication number
ATE299873T1
ATE299873T1 AT02743057T AT02743057T ATE299873T1 AT E299873 T1 ATE299873 T1 AT E299873T1 AT 02743057 T AT02743057 T AT 02743057T AT 02743057 T AT02743057 T AT 02743057T AT E299873 T1 ATE299873 T1 AT E299873T1
Authority
AT
Austria
Prior art keywords
methylamin
thiophen
methylamine
furan
derivatives
Prior art date
Application number
AT02743057T
Other languages
German (de)
English (en)
Inventor
Corinna Maul
Michael Przewosny
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of ATE299873T1 publication Critical patent/ATE299873T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT02743057T 2001-05-22 2002-05-21 Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate ATE299873T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10125145A DE10125145A1 (de) 2001-05-22 2001-05-22 Substituierte C-Furan-2-yl-methylamin- und C-Thiophen-2-yl-methylamin-Derivate
PCT/EP2002/005542 WO2002094802A1 (fr) 2001-05-22 2002-05-21 Derives substitues de c-furan-2-yl-methylamine et c-thiophen-2-yl-methylamine

Publications (1)

Publication Number Publication Date
ATE299873T1 true ATE299873T1 (de) 2005-08-15

Family

ID=7685874

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02743057T ATE299873T1 (de) 2001-05-22 2002-05-21 Substituierte c-furan-2-yl-methylamin- und c- thiophen-2-yl-methylamin-derivate

Country Status (17)

Country Link
US (2) US6878740B2 (fr)
EP (1) EP1392670B1 (fr)
JP (1) JP2004532246A (fr)
AR (1) AR035982A1 (fr)
AT (1) ATE299873T1 (fr)
AU (1) AU2002338989B2 (fr)
CA (1) CA2448038C (fr)
DE (2) DE10125145A1 (fr)
DK (1) DK1392670T3 (fr)
ES (1) ES2242869T3 (fr)
HU (1) HUP0401162A3 (fr)
MX (1) MXPA03010601A (fr)
PE (1) PE20021099A1 (fr)
PL (1) PL367535A1 (fr)
PT (1) PT1392670E (fr)
SI (1) SI1392670T1 (fr)
WO (1) WO2002094802A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0302094D0 (en) * 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) * 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
KR100553398B1 (ko) 2004-03-12 2006-02-16 한미약품 주식회사 티에노[3,2-ｃ]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
WO2011005660A1 (fr) 2009-07-08 2011-01-13 Valocor Therapeutics, Inc. Analogues de tofa utile dans le traitement de troubles ou états dermatologiques
EP2897589B1 (fr) * 2013-11-22 2018-01-03 Teva Branded Pharmaceutical Products R & D, Inc. Médicament inhalable
CN109153659A (zh) * 2016-05-31 2019-01-04 翰林大学产学研合作团队 五元杂环衍生物、其制备方法及包含其的药剂学组合物
CN112521357B (zh) * 2020-08-31 2021-10-08 深圳瑞健生物科技有限公司 一种长效低成瘾性hnk衍生物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3890445A (en) * 1973-01-05 1975-06-17 Richardson Merrell Inc Lactamimide derivatives useful as hypoglycemic agents
US3816457A (en) * 1973-01-05 1974-06-11 Richardson Merrell Inc Lactamimide derivatives
WO2001068816A1 (fr) 2000-03-13 2001-09-20 Smithkline Beecham Corporation Variant-3 du gene humain de l'histamine h3
DE10012820A1 (de) * 2000-03-16 2001-09-20 Bayer Ag Substituierte 1-Aryl-cyclopropylmethylamino-1,3,5-triazine
DE10059864A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate

Also Published As

Publication number Publication date
HUP0401162A3 (en) 2007-05-02
WO2002094802A1 (fr) 2002-11-28
ES2242869T3 (es) 2005-11-16
EP1392670B1 (fr) 2005-07-20
HUP0401162A2 (hu) 2004-10-28
DK1392670T3 (da) 2005-08-08
DE10125145A1 (de) 2002-11-28
PE20021099A1 (es) 2003-01-25
SI1392670T1 (sl) 2005-12-31
US7317034B2 (en) 2008-01-08
PL367535A1 (en) 2005-02-21
DE50203686D1 (en) 2005-08-25
CA2448038A1 (fr) 2002-11-28
AR035982A1 (es) 2004-07-28
JP2004532246A (ja) 2004-10-21
US20050148550A1 (en) 2005-07-07
US6878740B2 (en) 2005-04-12
AU2002338989B2 (en) 2007-06-07
MXPA03010601A (es) 2004-03-09
PT1392670E (pt) 2005-10-31
EP1392670A1 (fr) 2004-03-03
US20040152734A1 (en) 2004-08-05
CA2448038C (fr) 2010-09-28

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