MXPA03010601A - Derivados de c-furan-2-il-metilamina y c-tiofen-2-il-metilamina sustituidos. - Google Patents

Derivados de c-furan-2-il-metilamina y c-tiofen-2-il-metilamina sustituidos.

Info

Publication number
MXPA03010601A
MXPA03010601A MXPA03010601A MXPA03010601A MXPA03010601A MX PA03010601 A MXPA03010601 A MX PA03010601A MX PA03010601 A MXPA03010601 A MX PA03010601A MX PA03010601 A MXPA03010601 A MX PA03010601A MX PA03010601 A MXPA03010601 A MX PA03010601A
Authority
MX
Mexico
Prior art keywords
methylamine
derivatives
medicament
thiophen
furan
Prior art date
Application number
MXPA03010601A
Other languages
English (en)
Inventor
Przewosny Michael
Original Assignee
Gr Nenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gr Nenthal Gmbh filed Critical Gr Nenthal Gmbh
Publication of MXPA03010601A publication Critical patent/MXPA03010601A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion se refiere a derivados de C-furan-2-il-metilamina y C-tiofen-2-il-metilamina sustituidos de la formula general (I), procedimientos para su preparacion, medicamentos composiciones farmaceuticas conteniendolos, asi como su uso para la preparacion de analgesicos, para la preparacion de un anestesico local, de un antiarritmico, un antiemetico, un nootropico y/o de medicamento para el tratamiento y/o la prevencion de enfermedades cardiovasculares, de incontinencia urinaria, diarrea, prurito y/o inflamaciones y/o de un medicamento para el tratamiento de depresiones y/o de abuso de alcohol y/o de drogas y/o de medicamentos y/o de un medicamento para el aumento de alerta.
MXPA03010601A 2001-05-22 2002-05-21 Derivados de c-furan-2-il-metilamina y c-tiofen-2-il-metilamina sustituidos. MXPA03010601A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10125145A DE10125145A1 (de) 2001-05-22 2001-05-22 Substituierte C-Furan-2-yl-methylamin- und C-Thiophen-2-yl-methylamin-Derivate
PCT/EP2002/005542 WO2002094802A1 (de) 2001-05-22 2002-05-21 Substituierte c-furan-2-yl-methylamin- und c-thiophen-2-yl-methylamin-derivate

Publications (1)

Publication Number Publication Date
MXPA03010601A true MXPA03010601A (es) 2004-03-09

Family

ID=7685874

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03010601A MXPA03010601A (es) 2001-05-22 2002-05-21 Derivados de c-furan-2-il-metilamina y c-tiofen-2-il-metilamina sustituidos.

Country Status (17)

Country Link
US (2) US6878740B2 (es)
EP (1) EP1392670B1 (es)
JP (1) JP2004532246A (es)
AR (1) AR035982A1 (es)
AT (1) ATE299873T1 (es)
AU (1) AU2002338989B2 (es)
CA (1) CA2448038C (es)
DE (2) DE10125145A1 (es)
DK (1) DK1392670T3 (es)
ES (1) ES2242869T3 (es)
HU (1) HUP0401162A3 (es)
MX (1) MXPA03010601A (es)
PE (1) PE20021099A1 (es)
PL (1) PL367535A1 (es)
PT (1) PT1392670E (es)
SI (1) SI1392670T1 (es)
WO (1) WO2002094802A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0302094D0 (en) * 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) * 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
KR100553398B1 (ko) * 2004-03-12 2006-02-16 한미약품 주식회사 티에노[3,2-ｃ]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
US8884034B2 (en) 2009-07-08 2014-11-11 Dermira (Canada), Inc. TOFA analogs useful in treating dermatological disorders or conditions
JP6397025B2 (ja) * 2013-11-22 2018-09-26 テバ ブランデッド ファーマシューティカル プロダクツ アール アンド ディー インコーポレイテッド 吸引可能薬剤
EP3470404A1 (en) * 2016-05-31 2019-04-17 Industry Academic Cooperation Foundation, Hallym University Five-membered heterocyclic derivative, method for producing same, and pharmaceutical composition comprising same
CN112521357B (zh) * 2020-08-31 2021-10-08 深圳瑞健生物科技有限公司 一种长效低成瘾性hnk衍生物及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3890445A (en) * 1973-01-05 1975-06-17 Richardson Merrell Inc Lactamimide derivatives useful as hypoglycemic agents
US3816457A (en) * 1973-01-05 1974-06-11 Richardson Merrell Inc Lactamimide derivatives
WO2001068816A1 (en) 2000-03-13 2001-09-20 Smithkline Beecham Corporation Human histamine h3 gene variant-3
DE10012820A1 (de) * 2000-03-16 2001-09-20 Bayer Ag Substituierte 1-Aryl-cyclopropylmethylamino-1,3,5-triazine
DE10059864A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate

Also Published As

Publication number Publication date
DE50203686D1 (en) 2005-08-25
ATE299873T1 (de) 2005-08-15
US20050148550A1 (en) 2005-07-07
CA2448038A1 (en) 2002-11-28
US7317034B2 (en) 2008-01-08
HUP0401162A3 (en) 2007-05-02
JP2004532246A (ja) 2004-10-21
EP1392670B1 (de) 2005-07-20
PE20021099A1 (es) 2003-01-25
WO2002094802A1 (de) 2002-11-28
US20040152734A1 (en) 2004-08-05
AR035982A1 (es) 2004-07-28
DE10125145A1 (de) 2002-11-28
EP1392670A1 (de) 2004-03-03
CA2448038C (en) 2010-09-28
PL367535A1 (en) 2005-02-21
PT1392670E (pt) 2005-10-31
AU2002338989B2 (en) 2007-06-07
DK1392670T3 (da) 2005-08-08
SI1392670T1 (sl) 2005-12-31
US6878740B2 (en) 2005-04-12
HUP0401162A2 (hu) 2004-10-28
ES2242869T3 (es) 2005-11-16

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