ATE290600T1 - Herstellung von urokinase in pflanzlichen expressionssystemen - Google Patents

Herstellung von urokinase in pflanzlichen expressionssystemen

Info

Publication number
ATE290600T1
ATE290600T1 AT99930655T AT99930655T ATE290600T1 AT E290600 T1 ATE290600 T1 AT E290600T1 AT 99930655 T AT99930655 T AT 99930655T AT 99930655 T AT99930655 T AT 99930655T AT E290600 T1 ATE290600 T1 AT E290600T1
Authority
AT
Austria
Prior art keywords
urokinase
recombinant
urokinases
human
plant expression
Prior art date
Application number
AT99930655T
Other languages
English (en)
Inventor
Karen K Oishi
Da-Feng Zhou
Original Assignee
Croptech Dev Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Croptech Dev Corp filed Critical Croptech Dev Corp
Application granted granted Critical
Publication of ATE290600T1 publication Critical patent/ATE290600T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99930655T 1998-06-26 1999-06-25 Herstellung von urokinase in pflanzlichen expressionssystemen ATE290600T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9091198P 1998-06-26 1998-06-26
PCT/US1999/014292 WO2000000624A1 (en) 1998-06-26 1999-06-25 Production of urokinase in plant-based expression systems

Publications (1)

Publication Number Publication Date
ATE290600T1 true ATE290600T1 (de) 2005-03-15

Family

ID=29418292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930655T ATE290600T1 (de) 1998-06-26 1999-06-25 Herstellung von urokinase in pflanzlichen expressionssystemen

Country Status (6)

Country Link
EP (1) EP1088081B1 (de)
JP (1) JP2003525578A (de)
AT (1) ATE290600T1 (de)
AU (1) AU4714799A (de)
DE (1) DE69924110D1 (de)
WO (1) WO2000000624A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2718444B1 (de) * 2011-06-07 2017-12-27 iBio, Inc. In-vivo-deglycosylierung rekombinanter proteine durch co-expression mit pngase f
CN102260708A (zh) * 2011-07-15 2011-11-30 山东省农业科学院高新技术研究中心 硫堇蛋白类基因Rs-AFP1植物双元表达载体、构建方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI88932C (fi) * 1982-04-15 1993-07-26 Genentech Inc Framstaellning av funktionellt maenskligt urokinasprotein
DD263081A1 (de) * 1987-07-20 1988-12-21 Akad Wissenschaften Ddr Verfahren zum einfuehren von dns-sequenzen in das genom von hoeheren pflanzen
US5723755A (en) * 1995-05-16 1998-03-03 Francis E. Lefaivre Large scale production of human or animal proteins using plant bioreactors
US5929304A (en) * 1995-09-14 1999-07-27 Croptech Development Corporation Production of lysosomal enzymes in plant-based expression systems

Also Published As

Publication number Publication date
EP1088081A1 (de) 2001-04-04
WO2000000624A8 (en) 2000-09-14
DE69924110D1 (de) 2005-04-14
WO2000000624A1 (en) 2000-01-06
AU4714799A (en) 2000-01-17
EP1088081B1 (de) 2005-03-09
JP2003525578A (ja) 2003-09-02
WO2000000624A9 (en) 2000-11-02

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