ATE286396T1 - Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungen - Google Patents
Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungenInfo
- Publication number
- ATE286396T1 ATE286396T1 AT00935465T AT00935465T ATE286396T1 AT E286396 T1 ATE286396 T1 AT E286396T1 AT 00935465 T AT00935465 T AT 00935465T AT 00935465 T AT00935465 T AT 00935465T AT E286396 T1 ATE286396 T1 AT E286396T1
- Authority
- AT
- Austria
- Prior art keywords
- pruritus
- treatment
- riboflavin
- nicotinamide
- combination
- Prior art date
Links
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 title abstract 6
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 5
- 208000003251 Pruritus Diseases 0.000 title abstract 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 title abstract 4
- 235000005152 nicotinamide Nutrition 0.000 title abstract 3
- 239000011570 nicotinamide Substances 0.000 title abstract 3
- 229960003966 nicotinamide Drugs 0.000 title abstract 3
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 3
- 239000011664 nicotinic acid Substances 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 title abstract 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002477 riboflavin Drugs 0.000 title abstract 2
- 235000019192 riboflavin Nutrition 0.000 title abstract 2
- 239000002151 riboflavin Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 2
- 201000006370 kidney failure Diseases 0.000 abstract 2
- 208000028185 Angioedema Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 206010060875 Uraemic pruritus Diseases 0.000 abstract 1
- 208000024780 Urticaria Diseases 0.000 abstract 1
- 229930003270 Vitamin B Natural products 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 230000001524 infective effect Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000019156 vitamin B Nutrition 0.000 abstract 1
- 239000011720 vitamin B Substances 0.000 abstract 1
- 239000011708 vitamin B3 Substances 0.000 abstract 1
- 235000019160 vitamin B3 Nutrition 0.000 abstract 1
- -1 vitamin compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999RM000309A IT1306141B1 (it) | 1999-05-17 | 1999-05-17 | Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche. |
| PCT/IT2000/000196 WO2000069426A2 (en) | 1999-05-17 | 2000-05-17 | Combination of nicotinic acid or nicotinamide with riboflavin for the treatment of pruritus, itching and inflammation disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286396T1 true ATE286396T1 (de) | 2005-01-15 |
Family
ID=11406769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00935465T ATE286396T1 (de) | 1999-05-17 | 2000-05-17 | Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7026319B1 (de) |
| EP (1) | EP1178801B1 (de) |
| JP (1) | JP2002544225A (de) |
| CN (1) | CN1159013C (de) |
| AT (1) | ATE286396T1 (de) |
| AU (1) | AU774343B2 (de) |
| CA (1) | CA2373296C (de) |
| DE (1) | DE60017251T2 (de) |
| EA (1) | EA003792B1 (de) |
| ES (1) | ES2233384T3 (de) |
| IT (1) | IT1306141B1 (de) |
| WO (1) | WO2000069426A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1320776B1 (it) * | 2000-08-07 | 2003-12-10 | Giampiero Valletta | Composizione farmaceutica a base di un'associazione vitaminica per laterapia delle cefalee primarie |
| US6750234B2 (en) * | 2001-03-08 | 2004-06-15 | University Of Kentucky Research Foundation | Methods for increasing leptin levels using nicotinic acid compounds |
| AR041089A1 (es) * | 2003-05-15 | 2005-05-04 | Merck & Co Inc | Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas |
| US20040254202A1 (en) * | 2003-06-13 | 2004-12-16 | The Procter & Gamble Company | Method of promoting sleep using topical administration of vasoactive agents |
| EP2114154B1 (de) * | 2007-02-08 | 2013-08-28 | Merck Sharp & Dohme Corp. | Verfahren zur behandlung von atherosklerose, hyperlipidämien und verwandten erkrankungen |
| ES2396755T3 (es) * | 2008-03-28 | 2013-02-25 | Elanco Animal Health Ireland Limited | Uso de nicotinamida para tratar el comezón veraniego en caballos |
| US8128949B2 (en) * | 2008-04-14 | 2012-03-06 | John Mosher | Kit for insect bites |
| CA3291904A1 (en) * | 2012-06-27 | 2026-03-02 | Amazentis Sa | Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof |
| KR20180021280A (ko) * | 2016-08-18 | 2018-03-02 | 한양대학교 산학협력단 | 리보플라빈을 포함하는 가려움증 억제 또는 완화용 조성물 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2096712A1 (en) * | 1970-06-29 | 1972-02-25 | Giraux Georges | Steroid/b group vitamin compsns - for prevention and treatment of skin-photosensitivity disorders |
| US4265887A (en) * | 1979-12-11 | 1981-05-05 | Breskman Joseph S | Composition and method for treatment of hemorrhoids |
| JPS59502024A (ja) * | 1982-11-16 | 1984-12-06 | イレナ モッチャン マルス | リュウマチ性疾病治療剤 |
| US5053396A (en) * | 1985-08-27 | 1991-10-01 | Blass David H | Therapeutic composition |
| JPS63188627A (ja) * | 1987-01-31 | 1988-08-04 | Rooto Seiyaku Kk | 抗アレルギ−・抗炎症剤 |
| LU87145A1 (fr) * | 1988-02-26 | 1989-09-20 | Oreal | Methode pour ameliorer l'aspect esthetique de la peau a l'aide de melanges polyvitaminiques |
| NZ244270A (en) * | 1991-09-13 | 1995-07-26 | Eisai Co Ltd | Injectable composition comprising riboflavin |
| CN1080855A (zh) * | 1993-05-22 | 1994-01-19 | 黎均耀 | 维生素矿物质防癌复方 |
| DE4410238A1 (de) * | 1994-03-25 | 1995-09-28 | Beiersdorf Ag | Hautpflegemittel |
| US5496827A (en) * | 1994-07-15 | 1996-03-05 | Patrick; Jay | Compositions for the transdermal delivery of nutrients |
| ES2160829T3 (es) * | 1995-07-13 | 2001-11-16 | Basf Ag | Procedimiento para la obtencion de riboflavina por medio de microorganismos con actividad de isocitratoliasa modificada. |
| US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| US6248763B1 (en) * | 1998-05-19 | 2001-06-19 | Scivoletto Rosemarie | Composition for treating skin conditions |
| AU1223099A (en) * | 1997-11-24 | 1999-06-15 | Zhongming Zeng | Pharmaceutical formulation for stimulating the growth of gram-positive bacil li and increasing the acidity in vagina and the use thereof |
| AU735384B2 (en) * | 1998-03-16 | 2001-07-05 | Procter & Gamble Company, The | Compositions for regulating skin appearance |
-
1999
- 1999-05-17 IT IT1999RM000309A patent/IT1306141B1/it active
-
2000
- 2000-05-17 CN CNB008075948A patent/CN1159013C/zh not_active Expired - Lifetime
- 2000-05-17 AU AU51003/00A patent/AU774343B2/en not_active Ceased
- 2000-05-17 US US10/009,225 patent/US7026319B1/en not_active Expired - Lifetime
- 2000-05-17 JP JP2000617885A patent/JP2002544225A/ja active Pending
- 2000-05-17 WO PCT/IT2000/000196 patent/WO2000069426A2/en not_active Ceased
- 2000-05-17 ES ES00935465T patent/ES2233384T3/es not_active Expired - Lifetime
- 2000-05-17 CA CA002373296A patent/CA2373296C/en not_active Expired - Lifetime
- 2000-05-17 DE DE60017251T patent/DE60017251T2/de not_active Expired - Lifetime
- 2000-05-17 AT AT00935465T patent/ATE286396T1/de active
- 2000-05-17 EP EP00935465A patent/EP1178801B1/de not_active Expired - Lifetime
- 2000-05-17 EA EA200101205A patent/EA003792B1/ru not_active IP Right Cessation
-
2006
- 2006-01-30 US US11/342,903 patent/US7291625B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1178801A2 (de) | 2002-02-13 |
| DE60017251D1 (de) | 2005-02-10 |
| JP2002544225A (ja) | 2002-12-24 |
| WO2000069426A3 (en) | 2001-04-12 |
| CA2373296A1 (en) | 2000-11-23 |
| CN1159013C (zh) | 2004-07-28 |
| CN1350455A (zh) | 2002-05-22 |
| WO2000069426A2 (en) | 2000-11-23 |
| AU5100300A (en) | 2000-12-05 |
| ITRM990309A0 (it) | 1999-05-17 |
| US7291625B2 (en) | 2007-11-06 |
| EA003792B1 (ru) | 2003-10-30 |
| US20060178368A1 (en) | 2006-08-10 |
| CA2373296C (en) | 2008-07-15 |
| IT1306141B1 (it) | 2001-05-30 |
| EA200101205A1 (ru) | 2002-04-25 |
| US7026319B1 (en) | 2006-04-11 |
| AU774343B2 (en) | 2004-06-24 |
| DE60017251T2 (de) | 2005-12-15 |
| ITRM990309A1 (it) | 2000-11-17 |
| ES2233384T3 (es) | 2005-06-16 |
| EP1178801B1 (de) | 2005-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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