ATE286396T1 - Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungen - Google Patents
Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungenInfo
- Publication number
- ATE286396T1 ATE286396T1 AT00935465T AT00935465T ATE286396T1 AT E286396 T1 ATE286396 T1 AT E286396T1 AT 00935465 T AT00935465 T AT 00935465T AT 00935465 T AT00935465 T AT 00935465T AT E286396 T1 ATE286396 T1 AT E286396T1
- Authority
- AT
- Austria
- Prior art keywords
- pruritus
- treatment
- riboflavin
- nicotinamide
- combination
- Prior art date
Links
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 title abstract 6
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 5
- 208000003251 Pruritus Diseases 0.000 title abstract 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 title abstract 4
- 235000005152 nicotinamide Nutrition 0.000 title abstract 3
- 239000011570 nicotinamide Substances 0.000 title abstract 3
- 229960003966 nicotinamide Drugs 0.000 title abstract 3
- 235000001968 nicotinic acid Nutrition 0.000 title abstract 3
- 239000011664 nicotinic acid Substances 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 title abstract 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002477 riboflavin Drugs 0.000 title abstract 2
- 235000019192 riboflavin Nutrition 0.000 title abstract 2
- 239000002151 riboflavin Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 2
- 201000006370 kidney failure Diseases 0.000 abstract 2
- 208000028185 Angioedema Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 206010060875 Uraemic pruritus Diseases 0.000 abstract 1
- 208000024780 Urticaria Diseases 0.000 abstract 1
- 229930003270 Vitamin B Natural products 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 230000001524 infective effect Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000019156 vitamin B Nutrition 0.000 abstract 1
- 239000011720 vitamin B Substances 0.000 abstract 1
- 239000011708 vitamin B3 Substances 0.000 abstract 1
- 235000019160 vitamin B3 Nutrition 0.000 abstract 1
- -1 vitamin compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999RM000309A IT1306141B1 (it) | 1999-05-17 | 1999-05-17 | Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche. |
| PCT/IT2000/000196 WO2000069426A2 (en) | 1999-05-17 | 2000-05-17 | Combination of nicotinic acid or nicotinamide with riboflavin for the treatment of pruritus, itching and inflammation disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286396T1 true ATE286396T1 (de) | 2005-01-15 |
Family
ID=11406769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00935465T ATE286396T1 (de) | 1999-05-17 | 2000-05-17 | Kombination der nikotinsäure oder nikotinamid mit riboflavin für die behandlung der pruritus und entzündungstörungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7026319B1 (de) |
| EP (1) | EP1178801B1 (de) |
| JP (1) | JP2002544225A (de) |
| CN (1) | CN1159013C (de) |
| AT (1) | ATE286396T1 (de) |
| AU (1) | AU774343B2 (de) |
| CA (1) | CA2373296C (de) |
| DE (1) | DE60017251T2 (de) |
| EA (1) | EA003792B1 (de) |
| ES (1) | ES2233384T3 (de) |
| IT (1) | IT1306141B1 (de) |
| WO (1) | WO2000069426A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1320776B1 (it) | 2000-08-07 | 2003-12-10 | Giampiero Valletta | Composizione farmaceutica a base di un'associazione vitaminica per laterapia delle cefalee primarie |
| CN1265792C (zh) * | 2001-03-08 | 2006-07-26 | 肯塔基大学研究基金会 | 含有8－22个碳原子的烷基链的烟酸烷基酯在制备提高受试者瘦素水平的药物中的用途 |
| AR041089A1 (es) * | 2003-05-15 | 2005-05-04 | Merck & Co Inc | Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas |
| US20040254202A1 (en) * | 2003-06-13 | 2004-12-16 | The Procter & Gamble Company | Method of promoting sleep using topical administration of vasoactive agents |
| EP2114154B1 (de) * | 2007-02-08 | 2013-08-28 | Merck Sharp & Dohme Corp. | Verfahren zur behandlung von atherosklerose, hyperlipidämien und verwandten erkrankungen |
| DK2271342T3 (da) * | 2008-03-28 | 2012-10-29 | Elanco Animal Health Ireland | Anvendelse af nicotinamid til behandling af sommereksem hos heste |
| US8128949B2 (en) * | 2008-04-14 | 2012-03-06 | John Mosher | Kit for insect bites |
| KR20180021280A (ko) * | 2016-08-18 | 2018-03-02 | 한양대학교 산학협력단 | 리보플라빈을 포함하는 가려움증 억제 또는 완화용 조성물 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2096712A1 (en) | 1970-06-29 | 1972-02-25 | Giraux Georges | Steroid/b group vitamin compsns - for prevention and treatment of skin-photosensitivity disorders |
| US4265887A (en) * | 1979-12-11 | 1981-05-05 | Breskman Joseph S | Composition and method for treatment of hemorrhoids |
| JPS59502024A (ja) * | 1982-11-16 | 1984-12-06 | イレナ モッチャン マルス | リュウマチ性疾病治療剤 |
| US5053396A (en) * | 1985-08-27 | 1991-10-01 | Blass David H | Therapeutic composition |
| JPS63188627A (ja) * | 1987-01-31 | 1988-08-04 | Rooto Seiyaku Kk | 抗アレルギ−・抗炎症剤 |
| LU87145A1 (fr) * | 1988-02-26 | 1989-09-20 | Oreal | Methode pour ameliorer l'aspect esthetique de la peau a l'aide de melanges polyvitaminiques |
| NZ244270A (en) * | 1991-09-13 | 1995-07-26 | Eisai Co Ltd | Injectable composition comprising riboflavin |
| CN1080855A (zh) * | 1993-05-22 | 1994-01-19 | 黎均耀 | 维生素矿物质防癌复方 |
| DE4410238A1 (de) * | 1994-03-25 | 1995-09-28 | Beiersdorf Ag | Hautpflegemittel |
| US5496827A (en) * | 1994-07-15 | 1996-03-05 | Patrick; Jay | Compositions for the transdermal delivery of nutrients |
| KR100414490B1 (ko) * | 1995-07-13 | 2004-04-30 | 바스프 악티엔게젤샤프트 | 이소시트레이트리아제활성이변성된미생물에의한리보플라빈의제조방법 |
| US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
| US6248763B1 (en) * | 1998-05-19 | 2001-06-19 | Scivoletto Rosemarie | Composition for treating skin conditions |
| ATE306274T1 (de) * | 1997-11-24 | 2005-10-15 | Zhongming Zeng | Verwendung von dextrin, stärke oder glykogen zur behandlung von bakterieller vaginosis |
| CA2322587A1 (en) * | 1998-03-16 | 1999-09-23 | The Procter & Gamble Company | Compositions for regulating skin appearance |
-
1999
- 1999-05-17 IT IT1999RM000309A patent/IT1306141B1/it active
-
2000
- 2000-05-17 JP JP2000617885A patent/JP2002544225A/ja active Pending
- 2000-05-17 CA CA002373296A patent/CA2373296C/en not_active Expired - Lifetime
- 2000-05-17 AU AU51003/00A patent/AU774343B2/en not_active Ceased
- 2000-05-17 DE DE60017251T patent/DE60017251T2/de not_active Expired - Lifetime
- 2000-05-17 EA EA200101205A patent/EA003792B1/ru not_active IP Right Cessation
- 2000-05-17 US US10/009,225 patent/US7026319B1/en not_active Expired - Lifetime
- 2000-05-17 EP EP00935465A patent/EP1178801B1/de not_active Expired - Lifetime
- 2000-05-17 AT AT00935465T patent/ATE286396T1/de active
- 2000-05-17 ES ES00935465T patent/ES2233384T3/es not_active Expired - Lifetime
- 2000-05-17 WO PCT/IT2000/000196 patent/WO2000069426A2/en not_active Ceased
- 2000-05-17 CN CNB008075948A patent/CN1159013C/zh not_active Expired - Lifetime
-
2006
- 2006-01-30 US US11/342,903 patent/US7291625B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000069426A3 (en) | 2001-04-12 |
| EP1178801A2 (de) | 2002-02-13 |
| DE60017251D1 (de) | 2005-02-10 |
| WO2000069426A2 (en) | 2000-11-23 |
| DE60017251T2 (de) | 2005-12-15 |
| ITRM990309A0 (it) | 1999-05-17 |
| US20060178368A1 (en) | 2006-08-10 |
| CN1350455A (zh) | 2002-05-22 |
| EP1178801B1 (de) | 2005-01-05 |
| JP2002544225A (ja) | 2002-12-24 |
| US7026319B1 (en) | 2006-04-11 |
| ITRM990309A1 (it) | 2000-11-17 |
| CN1159013C (zh) | 2004-07-28 |
| EA200101205A1 (ru) | 2002-04-25 |
| ES2233384T3 (es) | 2005-06-16 |
| CA2373296C (en) | 2008-07-15 |
| EA003792B1 (ru) | 2003-10-30 |
| US7291625B2 (en) | 2007-11-06 |
| AU774343B2 (en) | 2004-06-24 |
| AU5100300A (en) | 2000-12-05 |
| IT1306141B1 (it) | 2001-05-30 |
| CA2373296A1 (en) | 2000-11-23 |
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| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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