ATE286251T1 - Immuntest unter verwendung von partikeln mit kaseinumhüllungen - Google Patents
Immuntest unter verwendung von partikeln mit kaseinumhüllungenInfo
- Publication number
- ATE286251T1 ATE286251T1 AT00905717T AT00905717T ATE286251T1 AT E286251 T1 ATE286251 T1 AT E286251T1 AT 00905717 T AT00905717 T AT 00905717T AT 00905717 T AT00905717 T AT 00905717T AT E286251 T1 ATE286251 T1 AT E286251T1
- Authority
- AT
- Austria
- Prior art keywords
- casein
- particles
- immunoassays
- active ingredients
- developed
- Prior art date
Links
- 239000005018 casein Substances 0.000 title abstract 9
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 title abstract 9
- 235000021240 caseins Nutrition 0.000 title abstract 9
- 239000002245 particle Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 3
- 238000003018 immunoassay Methods 0.000 abstract 3
- 239000006249 magnetic particle Substances 0.000 abstract 3
- 230000005298 paramagnetic effect Effects 0.000 abstract 3
- 238000000159 protein binding assay Methods 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000007790 solid phase Substances 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4731—Casein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
- G01N2446/84—Polymer coating, e.g. gelatin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/815—Carrier is a synthetic polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Paints Or Removers (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11757899P | 1999-01-27 | 1999-01-27 | |
| PCT/US2000/001749 WO2000045171A1 (en) | 1999-01-27 | 2000-01-26 | Immunoassays using casein coating of particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286251T1 true ATE286251T1 (de) | 2005-01-15 |
Family
ID=22373666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00905717T ATE286251T1 (de) | 1999-01-27 | 2000-01-26 | Immuntest unter verwendung von partikeln mit kaseinumhüllungen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6461874B1 (de) |
| EP (1) | EP1064552B1 (de) |
| JP (1) | JP2002535678A (de) |
| AT (1) | ATE286251T1 (de) |
| AU (1) | AU2736000A (de) |
| DE (1) | DE60017017T2 (de) |
| WO (1) | WO2000045171A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6815063B1 (en) | 1996-11-16 | 2004-11-09 | Nanomagnetics, Ltd. | Magnetic fluid |
| GB2319253A (en) | 1996-11-16 | 1998-05-20 | Eric Leigh Mayes | Composition, for use in a device, comprising a magnetic layer of domain-separated magnetic particles |
| US6713173B2 (en) | 1996-11-16 | 2004-03-30 | Nanomagnetics Limited | Magnetizable device |
| US6986942B1 (en) | 1996-11-16 | 2006-01-17 | Nanomagnetics Limited | Microwave absorbing structure |
| IES20050816A2 (en) * | 2005-12-06 | 2007-05-16 | Trinity Res Ltd | A method for preparing microbeads for use in an assay for determining the presence of antibodies to human immunodeficiency virus in a sample |
| EP2033619A1 (de) * | 2007-08-24 | 2009-03-11 | Basf Se | Verfahren zum Dispergieren von ionischen Nanopartikeln |
| EP2475707A1 (de) * | 2009-09-10 | 2012-07-18 | Marc Bonneau | Polymerisationsverfahren, im besonderen zur polymerisation von önologischen zusätzen und anhand dieses verfahrens hergestellte polymere |
| KR101444424B1 (ko) * | 2011-10-14 | 2014-09-29 | 한국생명공학연구원 | 두 종 입자를 이용한 다기능 생체물질 접합체의 제조방법 및 이로부터 제조된 다기능 생체물질 접합체 |
| CA2984506A1 (en) | 2015-05-01 | 2016-11-10 | BioLegend, Inc. | Stable nanomagnetic particle dispersions |
| WO2017190117A1 (en) * | 2016-04-30 | 2017-11-02 | BioLegend, Inc. | Compositions and methods for performing magnetibuoyant separations |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH587021A5 (de) * | 1974-06-07 | 1977-04-29 | Nestle Sa | |
| US4096586A (en) * | 1976-03-04 | 1978-06-20 | Societe D'assistance Technique Pour Produits Nestle S.A. | Solubilization of casein |
| US4459361A (en) | 1982-06-04 | 1984-07-10 | Angenics, Inc. | Ligand assay with one or two particulate reagents and filter |
| US4628037A (en) | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
| US4554088A (en) | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US4618502A (en) * | 1984-08-08 | 1986-10-21 | Beach Marvin F | Process for converting casein to caseinate |
| US4842758A (en) * | 1986-10-31 | 1989-06-27 | Colgate-Palmolive Company | Stabilized enzyme system for use in aqueous liquid built detergent compositions |
| US4828980A (en) | 1987-09-18 | 1989-05-09 | Eastman Kodak Company | Membrane structure coated with low pI protein or carbohydrate and methods of making and use |
| US4812414A (en) | 1987-09-18 | 1989-03-14 | Eastman Kodak Company | Immunoreactive reagent particles having tracer, receptor molecules and protein of pI less than 6 |
| DE3715485A1 (de) | 1987-05-09 | 1988-11-17 | Boehringer Mannheim Gmbh | Stabilisierung von ss-galactosidase |
| MY104234A (en) * | 1988-11-17 | 1994-02-28 | Becton Dickinson Co | Immunoassay on a preblocked solid surface |
| US5939272A (en) * | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| DE3919393A1 (de) * | 1989-06-14 | 1990-12-20 | Hoechst Ag | Verfahren zur stabilisierung von auf festphasen immobilisierten biologisch aktiven substanzen |
| US5164299A (en) * | 1990-03-20 | 1992-11-17 | E. I. Du Pont De Nemours And Company | Use of a mixture of conjugated and unconjugated solid phase binding reagent to enhance the performance of assays |
| US5091318A (en) * | 1990-04-13 | 1992-02-25 | Abbott Laboratories | Binding of allergens to a solid phase |
| US5541072A (en) * | 1994-04-18 | 1996-07-30 | Immunivest Corporation | Method for magnetic separation featuring magnetic particles in a multi-phase system |
| KR100305306B1 (ko) * | 1993-02-17 | 2001-11-22 | 존 펑크하우저 | 건식화학캐스케이드면역분석법및친화도분석법 |
| US5480872A (en) * | 1993-05-28 | 1996-01-02 | Abbott Laboratories | Method of providing enternal nutritional support to persons infected with human immunodeficiency virus |
| US5445936A (en) | 1993-09-15 | 1995-08-29 | Ciba Corning Diagnostics Corp. | Method for non-competitive binding assays |
| ATE191086T1 (de) * | 1994-07-27 | 2000-04-15 | Pilgrimm Herbert | Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung |
| US5639626A (en) * | 1994-11-15 | 1997-06-17 | Chiron Diagnostics Corporation | Reagents for specific binding assays |
| US5635363A (en) * | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
| US5851777A (en) * | 1996-02-05 | 1998-12-22 | Dade Behring Inc. | Homogeneous sol-sol assay |
-
2000
- 2000-01-26 DE DE60017017T patent/DE60017017T2/de not_active Expired - Fee Related
- 2000-01-26 AU AU27360/00A patent/AU2736000A/en not_active Abandoned
- 2000-01-26 WO PCT/US2000/001749 patent/WO2000045171A1/en not_active Ceased
- 2000-01-26 EP EP00905717A patent/EP1064552B1/de not_active Revoked
- 2000-01-26 JP JP2000596372A patent/JP2002535678A/ja not_active Withdrawn
- 2000-01-26 AT AT00905717T patent/ATE286251T1/de not_active IP Right Cessation
- 2000-01-26 US US09/491,139 patent/US6461874B1/en not_active Expired - Fee Related
-
2001
- 2001-12-21 US US10/029,541 patent/US6756234B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2736000A (en) | 2000-08-18 |
| EP1064552B1 (de) | 2004-12-29 |
| US6756234B2 (en) | 2004-06-29 |
| US20020090638A1 (en) | 2002-07-11 |
| JP2002535678A (ja) | 2002-10-22 |
| DE60017017D1 (de) | 2005-02-03 |
| EP1064552A1 (de) | 2001-01-03 |
| WO2000045171A1 (en) | 2000-08-03 |
| US6461874B1 (en) | 2002-10-08 |
| DE60017017T2 (de) | 2006-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |