ATE285772T1 - Verwendung von indol-2,3-dione-3-oximderivate als ampa-antagonisten - Google Patents
Verwendung von indol-2,3-dione-3-oximderivate als ampa-antagonistenInfo
- Publication number
- ATE285772T1 ATE285772T1 AT99910150T AT99910150T ATE285772T1 AT E285772 T1 ATE285772 T1 AT E285772T1 AT 99910150 T AT99910150 T AT 99910150T AT 99910150 T AT99910150 T AT 99910150T AT E285772 T1 ATE285772 T1 AT E285772T1
- Authority
- AT
- Austria
- Prior art keywords
- dione
- indole
- oxime derivatives
- ampa antagonists
- ampa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK45298 | 1998-03-31 | ||
DK46298 | 1998-04-01 | ||
PCT/DK1999/000194 WO1999049864A1 (en) | 1998-03-31 | 1999-03-30 | Indole-2,3-dione-3-oxime derivatives for therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE285772T1 true ATE285772T1 (de) | 2005-01-15 |
Family
ID=26064032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99910150T ATE285772T1 (de) | 1998-03-31 | 1999-03-30 | Verwendung von indol-2,3-dione-3-oximderivate als ampa-antagonisten |
Country Status (10)
Country | Link |
---|---|
US (1) | US6239128B1 (de) |
EP (1) | EP1066037B1 (de) |
JP (1) | JP2002509885A (de) |
AT (1) | ATE285772T1 (de) |
AU (1) | AU751414B2 (de) |
BG (1) | BG104801A (de) |
CA (1) | CA2326576A1 (de) |
DE (1) | DE69922936T2 (de) |
NZ (1) | NZ507259A (de) |
WO (1) | WO1999049864A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2369746A1 (en) * | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
CA2394292A1 (en) * | 2000-01-24 | 2001-08-02 | Neurosearch A/S | Isatine derivatives with neurotrophic activity |
ES2250667T3 (es) | 2001-07-13 | 2006-04-16 | PHARMACIA & UPJOHN COMPANY LLC | Hexahidroazepino(4,5-g)indoles e indolinas como ligandos del receptor 5-ht. |
MXPA05002056A (es) * | 2002-08-22 | 2005-06-08 | Neurosearch As | Metodo para la preparacion de enantiomeros de derivados de indol-2,3-diona-3-oxima. |
AU2006317545B2 (en) * | 2005-11-23 | 2012-04-12 | Aros Pharma Aps | Compositions and methods for modulating gated ion channels |
CA2652307A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
US20080021034A1 (en) * | 2006-04-10 | 2008-01-24 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
US20100041691A1 (en) * | 2006-09-12 | 2010-02-18 | Neurosearch A/S | Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein |
CN102653538A (zh) * | 2011-03-04 | 2012-09-05 | 爱斯医药科技(南京)有限公司 | Spd-502的制备方法 |
CN104725372B (zh) * | 2015-01-28 | 2017-02-22 | 天津科技大学 | 四环吲哚生物碱衍生物及其制备和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994026747A1 (en) * | 1993-05-13 | 1994-11-24 | Neurosearch A/S | Ampa antagonists and a method of treatment therewith |
GB9418357D0 (en) * | 1994-09-12 | 1994-11-02 | Chiroscience Ltd | Amidation process |
EE03355B1 (et) * | 1994-09-14 | 2001-02-15 | Neurosearch A/S | Indool-2,3-dioon-3-oksiimi derivaadid, nende valmistamine ja kasutamine |
UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
-
1999
- 1999-03-30 WO PCT/DK1999/000194 patent/WO1999049864A1/en active IP Right Grant
- 1999-03-30 NZ NZ507259A patent/NZ507259A/en unknown
- 1999-03-30 AT AT99910150T patent/ATE285772T1/de not_active IP Right Cessation
- 1999-03-30 CA CA002326576A patent/CA2326576A1/en not_active Abandoned
- 1999-03-30 AU AU29219/99A patent/AU751414B2/en not_active Ceased
- 1999-03-30 DE DE69922936T patent/DE69922936T2/de not_active Expired - Lifetime
- 1999-03-30 EP EP99910150A patent/EP1066037B1/de not_active Expired - Lifetime
- 1999-03-30 JP JP2000540828A patent/JP2002509885A/ja not_active Withdrawn
-
2000
- 2000-09-27 BG BG104801A patent/BG104801A/xx unknown
- 2000-09-29 US US09/675,214 patent/US6239128B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2326576A1 (en) | 1999-10-07 |
AU2921999A (en) | 1999-10-18 |
US6239128B1 (en) | 2001-05-29 |
DE69922936D1 (de) | 2005-02-03 |
DE69922936T2 (de) | 2005-12-08 |
BG104801A (en) | 2001-04-30 |
NZ507259A (en) | 2003-07-25 |
EP1066037A1 (de) | 2001-01-10 |
JP2002509885A (ja) | 2002-04-02 |
EP1066037B1 (de) | 2004-12-29 |
AU751414B2 (en) | 2002-08-15 |
WO1999049864A1 (en) | 1999-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1066037 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |