ATE283044T1 - Compactin zur behandlung von entzündungen - Google Patents

Compactin zur behandlung von entzündungen

Info

Publication number
ATE283044T1
ATE283044T1 AT93904788T AT93904788T ATE283044T1 AT E283044 T1 ATE283044 T1 AT E283044T1 AT 93904788 T AT93904788 T AT 93904788T AT 93904788 T AT93904788 T AT 93904788T AT E283044 T1 ATE283044 T1 AT E283044T1
Authority
AT
Austria
Prior art keywords
inhibitors
compactin
inflammation
treatment
disclosed
Prior art date
Application number
AT93904788T
Other languages
English (en)
Inventor
Gary M Bokoch
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE283044T1 publication Critical patent/ATE283044T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ignition Installations For Internal Combustion Engines (AREA)
AT93904788T 1992-01-31 1993-01-21 Compactin zur behandlung von entzündungen ATE283044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/829,766 US5244916A (en) 1992-01-31 1992-01-31 Inhibition of respiratory burst using posttranslational modification inhibitors
PCT/US1993/000871 WO1993014749A1 (en) 1992-01-31 1993-01-21 Inhibition of respiratory burst using posttranslational modification inhibitors

Publications (1)

Publication Number Publication Date
ATE283044T1 true ATE283044T1 (de) 2004-12-15

Family

ID=25255499

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93904788T ATE283044T1 (de) 1992-01-31 1993-01-21 Compactin zur behandlung von entzündungen

Country Status (6)

Country Link
US (1) US5244916A (de)
EP (1) EP0727987B1 (de)
AT (1) ATE283044T1 (de)
CA (1) CA2129235C (de)
DE (1) DE69333711T2 (de)
WO (1) WO1993014749A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587402A (en) * 1992-04-09 1996-12-24 Wisconsin Alumni Research Foundation Regression of mammalian leukemia cell tumors
US5470877A (en) * 1992-04-09 1995-11-28 Wisconsin Alumni Research Foundation Uses of perillic acid methyl ester
US5726155A (en) * 1993-08-02 1998-03-10 The Scripps Research Institute Regulation of oxidative burst using LMWG-derived peptides and analogs
US5668171A (en) * 1993-11-08 1997-09-16 Board Of Regents, The University Of Texas System Halogenated mevalonate compositions and uses thereof in ras-dependent cell growth
GB2285047B (en) * 1993-12-21 1998-04-15 Yamanouchi U K Ltd Polypeptides which inhibit the NADPH oxidase complex
US5763496A (en) * 1995-11-27 1998-06-09 The Research Foundation Of State University Of New York Prevention of atherosclerosis using NADPH oxidase inhibitors
WO1999026657A1 (en) 1997-11-25 1999-06-03 Musc Foundation For Research Development Inhibitors of nitric oxide synthase
US20060141036A1 (en) * 1997-12-12 2006-06-29 Andrx Labs Llc HMG-CoA reductase inhibitor extended release formulation
US5916595A (en) * 1997-12-12 1999-06-29 Andrx Pharmaceutials, Inc. HMG co-reductase inhibitor
US20040029962A1 (en) * 1997-12-12 2004-02-12 Chih-Ming Chen HMG-COA reductase inhibitor extended release formulation
US6242473B1 (en) * 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
US20010006656A1 (en) * 1999-02-17 2001-07-05 University Of Washington Methods and compositions for inhibiting inflammation associated with pulmonary disease
IL149524A0 (en) * 1999-11-08 2002-11-10 Andrx Corp HMG-CoA REDUCTASE INHIBITOR EXTENDED RELEASE FORMULATIONS
US20020010128A1 (en) * 2000-04-13 2002-01-24 Parks Thomas P. Treatment of hyperproliferative, inflammatory and related mucocutaneous disorders using inhibitors of mevalonate synthesis and metabolism
US20030195167A1 (en) * 2002-04-15 2003-10-16 Kowa Co., Ltd. PTX3-gene expression inhibitor
US20150328185A1 (en) 2012-08-22 2015-11-19 Universidad De Los Andes Use of statins for periodontaldisesae and bone regeneration
FR3030248B1 (fr) 2014-12-22 2018-03-23 L'oreal Association derive d'acide pyridine-dicarboxylique/agent anti-oxydant particulier

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2111384A (en) * 1981-08-03 1983-07-06 Wynne David Improvement in preventative and curative medicine
US5593966A (en) * 1989-03-31 1997-01-14 The United States Of America As Represented By The Department Of Health And Human Services Peptide derivatives of cytochrome b558 and their use as medicaments
AU7699191A (en) * 1990-03-30 1991-10-30 Amgen, Inc. Respiratory burst suppression factor
DE69331385T2 (de) * 1992-06-16 2002-11-14 Icn Pharmaceuticals, Inc. Zusammensetzung zur hautbehandlung
JP2004351839A (ja) * 2003-05-30 2004-12-16 Brother Ind Ltd 接合構造及び接合構造の製造方法

Also Published As

Publication number Publication date
EP0727987A4 (de) 1998-03-11
DE69333711D1 (de) 2004-12-30
EP0727987A1 (de) 1996-08-28
AU670259B2 (en) 1996-07-11
US5244916A (en) 1993-09-14
EP0727987B1 (de) 2004-11-24
AU3602793A (en) 1993-09-01
CA2129235C (en) 2004-04-06
DE69333711T2 (de) 2005-12-15
CA2129235A1 (en) 1993-08-05
WO1993014749A1 (en) 1993-08-05

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