ATE277624T1 - Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungen - Google Patents
Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungenInfo
- Publication number
- ATE277624T1 ATE277624T1 AT98922090T AT98922090T ATE277624T1 AT E277624 T1 ATE277624 T1 AT E277624T1 AT 98922090 T AT98922090 T AT 98922090T AT 98922090 T AT98922090 T AT 98922090T AT E277624 T1 ATE277624 T1 AT E277624T1
- Authority
- AT
- Austria
- Prior art keywords
- nocc
- carboxymethyl
- chitosane
- compositions
- covalently bonded
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/852,005 US5888988A (en) | 1995-05-08 | 1997-05-06 | Covalently linked N,O-carboxymethylchitosan and uses thereof |
PCT/US1998/009001 WO1998050050A1 (en) | 1997-05-06 | 1998-05-04 | Covalently linked n,o-carboxymethylchitosan and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE277624T1 true ATE277624T1 (de) | 2004-10-15 |
Family
ID=25312270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98922090T ATE277624T1 (de) | 1997-05-06 | 1998-05-04 | Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungen |
Country Status (8)
Country | Link |
---|---|
US (1) | US5888988A (de) |
EP (1) | EP1003526B1 (de) |
JP (1) | JP2001524156A (de) |
AT (1) | ATE277624T1 (de) |
CA (1) | CA2288983C (de) |
DE (1) | DE69826684T2 (de) |
ES (1) | ES2230692T3 (de) |
WO (1) | WO1998050050A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6645947B1 (en) * | 1999-05-20 | 2003-11-11 | Chitogenics, Inc. | Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins |
DE60042833D1 (de) | 1999-10-07 | 2009-10-08 | Coloplast As | Chitosan enthaltender artikel zur wundbehandlung |
KR20010107068A (ko) * | 2000-05-25 | 2001-12-07 | 김정식 | 유착방지제 |
AU2002252565A1 (en) * | 2002-03-28 | 2003-10-13 | Chitogenics, Inc. | Adherent n,o-carboxymethylchitosan drug delivery devices for moist tissue and methods of their use |
US7456267B2 (en) * | 2004-03-25 | 2008-11-25 | Kytogenics Pharmaceuticals, Inc. | N-acylated chitinous polymers and methods of use thereof |
WO2006028110A1 (ja) * | 2004-09-07 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | 水溶性ヒアルロン酸修飾物の製造方法 |
CA2481491A1 (en) * | 2004-09-14 | 2006-03-14 | Le Groupe Lysac Inc. | Amidinated or guanidinated polysaccharides, their use as absorbents and a process for producing same |
TW200643033A (en) * | 2005-03-08 | 2006-12-16 | Chugai Pharmaceutical Co Ltd | Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue |
US9119901B2 (en) | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
US20070031467A1 (en) * | 2005-08-04 | 2007-02-08 | Abrahams John M | Composition and method for vascular embolization |
US7854923B2 (en) * | 2006-04-18 | 2010-12-21 | Endomedix, Inc. | Biopolymer system for tissue sealing |
US20080075657A1 (en) * | 2006-04-18 | 2008-03-27 | Abrahams John M | Biopolymer system for tissue sealing |
US20090010982A1 (en) * | 2006-04-18 | 2009-01-08 | Endomedix, Inc. | Biocompatible adherent sheet for tissue sealing |
US20070243130A1 (en) * | 2006-04-18 | 2007-10-18 | Weiliam Chen | Biopolymer system for tissue sealing |
CN101848739A (zh) | 2007-08-28 | 2010-09-29 | T·阿萨纳夏季斯 | 手术用水凝胶 |
JP5864429B2 (ja) | 2009-11-09 | 2016-02-17 | スポットライト テクノロジー パートナーズ エルエルシーSpotlight Technology Partners Llc | 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット |
TWI399385B (zh) * | 2009-12-29 | 2013-06-21 | Univ Vanung | Chitosan Derivatives and Their Preparation |
EP2737902A1 (de) * | 2012-11-28 | 2014-06-04 | Zarzatech, Inc. | Zusammensetzungen mit Cimetindin und n,o-Carboxymethylchitosan zur Prävention und Therapie von Pathologien der Haut und der Mukosemembranen und im Feld der Zahnheilkunde |
CN106046397A (zh) * | 2016-06-28 | 2016-10-26 | 深圳市阳光之路生物材料科技有限公司 | 一种关节润滑材料及其制备方法 |
US10590257B2 (en) | 2016-09-26 | 2020-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications |
US11969526B2 (en) | 2017-04-03 | 2024-04-30 | The Board Of Trustees Of The Leland Stanford Junior University | Adhesion prevention with shear-thinning polymeric hydrogels |
US11975123B2 (en) | 2018-04-02 | 2024-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Adhesion prevention with shear-thinning polymeric hydrogels |
US10517988B1 (en) | 2018-11-19 | 2019-12-31 | Endomedix, Inc. | Methods and compositions for achieving hemostasis and stable blood clot formation |
CN115054734B (zh) * | 2022-07-05 | 2024-01-05 | 诺一迈尔(山东)医学科技有限公司 | 一种可塑性复合骨修复支架及其制备方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4141973A (en) * | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
US4424346A (en) * | 1981-06-04 | 1984-01-03 | Canadian Patents And Development Ltd. | Derivatives of chitins, chitosans and other polysaccharides |
SE456346B (sv) * | 1984-07-23 | 1988-09-26 | Pharmacia Ab | Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning |
US4619995A (en) * | 1984-12-24 | 1986-10-28 | Nova Chem Limited | N,O-carboxymethyl chitosan and preparative method therefor |
US4819617A (en) * | 1986-09-04 | 1989-04-11 | University Of Florida | Viscoelastic material for ophthalmic surgery |
US5080893A (en) * | 1988-05-31 | 1992-01-14 | University Of Florida | Method for preventing surgical adhesions using a dilute solution of polymer |
US5023090A (en) * | 1989-08-16 | 1991-06-11 | Levin Robert H | Topical compositions containing LYCD and other topically active medicinal ingredients for the treatment of ACNE |
US5140016A (en) * | 1988-05-31 | 1992-08-18 | University Of Florida | Method and composition for preventing surgical adhesions using a dilute solution of polymer |
US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
US5462990A (en) * | 1990-10-15 | 1995-10-31 | Board Of Regents, The University Of Texas System | Multifunctional organic polymers |
US5412084A (en) * | 1991-10-09 | 1995-05-02 | Nova Chem Limited | N-O-carboxymethylchitosonium carboxylate salts |
AU3235593A (en) * | 1991-12-20 | 1993-07-28 | Howmedica Inc. | Process for insolubilizing N-carboxyalkyl derivatives of chitosan |
US5411988A (en) * | 1993-10-27 | 1995-05-02 | Bockow; Barry I. | Compositions and methods for inhibiting inflammation and adhesion formation |
EP0665022A1 (de) * | 1994-01-28 | 1995-08-02 | Prodex, Inc. | Viskoelastische Lösung aus N,O-Carboxymethylchitosan zur opthalmischen Verwendung |
GB9421969D0 (en) * | 1994-10-28 | 1994-12-21 | Innovative Tech Ltd | Wound treatment composition |
US5679658A (en) * | 1995-05-08 | 1997-10-21 | Chitogenics, Inc. | N,O-carbonxymethylchitosan for prevention of surgical adhesions |
WO1996041818A1 (en) * | 1995-06-09 | 1996-12-27 | Drohan William N | Chitin hydrogels, methods of their production and use |
CA2192725C (en) * | 1995-12-28 | 2004-04-20 | Kenji Tsujihara | Camptothecin derivatives |
-
1997
- 1997-05-06 US US08/852,005 patent/US5888988A/en not_active Expired - Lifetime
-
1998
- 1998-05-04 AT AT98922090T patent/ATE277624T1/de not_active IP Right Cessation
- 1998-05-04 CA CA2288983A patent/CA2288983C/en not_active Expired - Fee Related
- 1998-05-04 EP EP98922090A patent/EP1003526B1/de not_active Expired - Lifetime
- 1998-05-04 ES ES98922090T patent/ES2230692T3/es not_active Expired - Lifetime
- 1998-05-04 WO PCT/US1998/009001 patent/WO1998050050A1/en active IP Right Grant
- 1998-05-04 DE DE69826684T patent/DE69826684T2/de not_active Expired - Lifetime
- 1998-05-04 JP JP54831198A patent/JP2001524156A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2001524156A (ja) | 2001-11-27 |
CA2288983A1 (en) | 1998-11-12 |
DE69826684D1 (de) | 2004-11-04 |
EP1003526A4 (de) | 2000-05-31 |
WO1998050050A1 (en) | 1998-11-12 |
EP1003526A1 (de) | 2000-05-31 |
CA2288983C (en) | 2010-07-20 |
DE69826684T2 (de) | 2005-10-06 |
ES2230692T3 (es) | 2005-05-01 |
EP1003526B1 (de) | 2004-09-29 |
US5888988A (en) | 1999-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |