ATE272072T1 - Verfahren zur reinigung von menschlichem interleukin-1 rezeptor antagonist aus rekombinanten e.coli - Google Patents
Verfahren zur reinigung von menschlichem interleukin-1 rezeptor antagonist aus rekombinanten e.coliInfo
- Publication number
- ATE272072T1 ATE272072T1 AT97923960T AT97923960T ATE272072T1 AT E272072 T1 ATE272072 T1 AT E272072T1 AT 97923960 T AT97923960 T AT 97923960T AT 97923960 T AT97923960 T AT 97923960T AT E272072 T1 ATE272072 T1 AT E272072T1
- Authority
- AT
- Austria
- Prior art keywords
- coli
- recombinant
- value
- receptor antagonist
- human interleukin
- Prior art date
Links
- 101001076407 Homo sapiens Interleukin-1 receptor antagonist protein Proteins 0.000 title abstract 4
- 102000046824 human IL1RN Human genes 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 3
- 102000051628 Interleukin-1 receptor antagonist Human genes 0.000 abstract 2
- 239000008366 buffered solution Substances 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 229940119178 Interleukin 1 receptor antagonist Drugs 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 239000003407 interleukin 1 receptor blocking agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96109153 | 1996-06-07 | ||
| PCT/EP1997/002591 WO1997047650A1 (en) | 1996-06-07 | 1997-05-21 | Process for the purification of human interleukin-1 receptor antagonist from recombinant e. coli |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272072T1 true ATE272072T1 (de) | 2004-08-15 |
Family
ID=8222862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97923960T ATE272072T1 (de) | 1996-06-07 | 1997-05-21 | Verfahren zur reinigung von menschlichem interleukin-1 rezeptor antagonist aus rekombinanten e.coli |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0938501B1 (de) |
| JP (1) | JP2000512143A (de) |
| AT (1) | ATE272072T1 (de) |
| AU (1) | AU717003B2 (de) |
| CA (1) | CA2257294C (de) |
| DE (1) | DE69730041T2 (de) |
| DK (1) | DK0938501T3 (de) |
| ES (1) | ES2221688T3 (de) |
| IL (1) | IL127155A (de) |
| PT (1) | PT938501E (de) |
| WO (1) | WO1997047650A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9927801D0 (en) * | 1999-11-24 | 2000-01-26 | Danisco | Method |
| WO2001041792A1 (en) * | 1999-12-10 | 2001-06-14 | Amgen, Inc. | Interleukin-1 receptor antagonist-like molecules and uses thereof |
| US20080166762A1 (en) * | 2006-09-27 | 2008-07-10 | Reliance Life Science Pvt.Ltd. | HETEROLOGOUS PRODUCTION OF INTERLEUKIN 1 RECEPTOR ANTAGONIST (IL-1Ra) IN PICHIA PASTORIS |
| JP2010515441A (ja) * | 2007-01-15 | 2010-05-13 | アップフロント・クロマトグラフィ・アクティーゼルスカブ | 原材料からのバイオ燃料およびタンパク質の製造 |
| DE202007002869U1 (de) | 2007-02-27 | 2008-07-10 | Ds Dichtungstechnik Gmbh | Dichtring und Steckmuffenverbindung |
| JP2014522868A (ja) * | 2011-07-29 | 2014-09-08 | イレブン・バイオセラピユーテイクス・インコーポレイテツド | 精製タンパク質 |
| EP2682168A1 (de) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Reinigung biologischer Moleküle |
| EP3844170A1 (de) | 2018-08-29 | 2021-07-07 | Merck Biodevelopment S.A.S. | Neues reinigungsverfahren |
-
1997
- 1997-05-21 JP JP10501109A patent/JP2000512143A/ja not_active Ceased
- 1997-05-21 DE DE69730041T patent/DE69730041T2/de not_active Expired - Lifetime
- 1997-05-21 EP EP97923960A patent/EP0938501B1/de not_active Expired - Lifetime
- 1997-05-21 AT AT97923960T patent/ATE272072T1/de active
- 1997-05-21 AU AU29586/97A patent/AU717003B2/en not_active Ceased
- 1997-05-21 DK DK97923960T patent/DK0938501T3/da active
- 1997-05-21 WO PCT/EP1997/002591 patent/WO1997047650A1/en not_active Ceased
- 1997-05-21 ES ES97923960T patent/ES2221688T3/es not_active Expired - Lifetime
- 1997-05-21 IL IL127155A patent/IL127155A/en not_active IP Right Cessation
- 1997-05-21 PT PT97923960T patent/PT938501E/pt unknown
- 1997-05-21 CA CA002257294A patent/CA2257294C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69730041D1 (de) | 2004-09-02 |
| ES2221688T3 (es) | 2005-01-01 |
| DE69730041T2 (de) | 2005-07-21 |
| DK0938501T3 (da) | 2004-11-15 |
| CA2257294A1 (en) | 1997-12-18 |
| EP0938501A1 (de) | 1999-09-01 |
| AU2958697A (en) | 1998-01-07 |
| CA2257294C (en) | 2006-03-14 |
| JP2000512143A (ja) | 2000-09-19 |
| AU717003B2 (en) | 2000-03-16 |
| PT938501E (pt) | 2004-11-30 |
| IL127155A0 (en) | 1999-09-22 |
| WO1997047650A1 (en) | 1997-12-18 |
| IL127155A (en) | 2007-05-15 |
| EP0938501B1 (de) | 2004-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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