ATE271381T1 - Transdermale verabreichung basischer wirkstoffe unter verwendung unpolarer haftsysteme und saurer lösungsvermittler - Google Patents
Transdermale verabreichung basischer wirkstoffe unter verwendung unpolarer haftsysteme und saurer lösungsvermittlerInfo
- Publication number
- ATE271381T1 ATE271381T1 AT98908760T AT98908760T ATE271381T1 AT E271381 T1 ATE271381 T1 AT E271381T1 AT 98908760 T AT98908760 T AT 98908760T AT 98908760 T AT98908760 T AT 98908760T AT E271381 T1 ATE271381 T1 AT E271381T1
- Authority
- AT
- Austria
- Prior art keywords
- providers
- transdermal administration
- active ingredients
- basic active
- adhesion systems
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 239000003623 enhancer Substances 0.000 abstract 3
- 230000007928 solubilization Effects 0.000 abstract 3
- 238000005063 solubilization Methods 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 238000001647 drug administration Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002888 oleic acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/808,211 US5879701A (en) | 1997-02-28 | 1997-02-28 | Transdermal delivery of basic drugs using nonpolar adhesive systems and acidic solubilizing agents |
| PCT/US1998/003832 WO1998037870A1 (en) | 1997-02-28 | 1998-02-27 | Transdermal delivery of basic drugs using nonpolar adhesive systems and acidic solubilizing agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE271381T1 true ATE271381T1 (de) | 2004-08-15 |
Family
ID=25198190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98908760T ATE271381T1 (de) | 1997-02-28 | 1998-02-27 | Transdermale verabreichung basischer wirkstoffe unter verwendung unpolarer haftsysteme und saurer lösungsvermittler |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5879701A (de) |
| EP (1) | EP0910353B1 (de) |
| JP (1) | JP2000509734A (de) |
| AT (1) | ATE271381T1 (de) |
| AU (1) | AU6670998A (de) |
| CA (1) | CA2252772C (de) |
| DE (1) | DE69825116T2 (de) |
| DK (1) | DK0910353T3 (de) |
| ES (1) | ES2226102T3 (de) |
| PT (1) | PT910353E (de) |
| WO (1) | WO1998037870A1 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| US6294188B1 (en) | 1998-07-09 | 2001-09-25 | Aviana Biopharm Inc. | Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women |
| US6280763B1 (en) | 1999-05-10 | 2001-08-28 | Pierce Management, Llc | Apparatus and method for transdermal delivery of bupropion |
| USRE44145E1 (en) | 2000-07-07 | 2013-04-09 | A.V. Topchiev Institute Of Petrochemical Synthesis | Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties |
| DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| FR2814368B1 (fr) * | 2000-09-26 | 2004-05-07 | Pf Medicament | Preparation pharmaceutique a base d'oxans |
| DK1335689T3 (da) | 2000-10-23 | 2010-06-14 | Euro Celtique Sa | System til transdermal indgivelse af loratadin og anvendelse deraf |
| US7018649B2 (en) * | 2000-10-23 | 2006-03-28 | Euro-Celtique, S.A. | Felodipine transdermal device and methods |
| WO2002054996A2 (en) * | 2000-10-23 | 2002-07-18 | Euro Celtique Sa | Terazosin transdermal device and methods |
| US6682757B1 (en) | 2000-11-16 | 2004-01-27 | Euro-Celtique, S.A. | Titratable dosage transdermal delivery system |
| US8840918B2 (en) * | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
| US8206738B2 (en) | 2001-05-01 | 2012-06-26 | Corium International, Inc. | Hydrogel compositions with an erodible backing member |
| US20050215727A1 (en) | 2001-05-01 | 2005-09-29 | Corium | Water-absorbent adhesive compositions and associated methods of manufacture and use |
| CA2445086C (en) * | 2001-05-01 | 2008-04-08 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions |
| US20050113510A1 (en) * | 2001-05-01 | 2005-05-26 | Feldstein Mikhail M. | Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components |
| EP1390084B1 (de) * | 2001-05-01 | 2011-03-23 | A.V. Topchiev Institute of Petrochemical Synthesis | Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung |
| US8541021B2 (en) * | 2001-05-01 | 2013-09-24 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions demonstrating phase separation on contact with aqueous media |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US8496960B2 (en) * | 2001-10-23 | 2013-07-30 | Purdue Pharma L.P. | Terazosin transdermal device and methods |
| US20030199584A1 (en) * | 2002-04-11 | 2003-10-23 | Ahluwalia Gurpreet S. | Reduction of hair growth |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| NZ537991A (en) * | 2002-08-30 | 2007-08-31 | Alza Corp | Embossable and writable multilaminate backing construction |
| EP1426049B1 (de) * | 2002-12-02 | 2005-05-18 | Schwarz Pharma Ag | Verabreichung von Rotigotine zur Behandlung der Parkinson'schen Krankheit durch Iontophorese |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| US20050096311A1 (en) * | 2003-10-30 | 2005-05-05 | Cns Response | Compositions and methods for treatment of nervous system disorders |
| KR20070007299A (ko) | 2004-01-30 | 2007-01-15 | 코리움 인터네셔널, 인크. | 활성제의 전달을 위한 급속 용해 필름 |
| AU2005271259B2 (en) | 2004-08-05 | 2012-01-19 | A.V. Topchiev Institute Of Petrochemical Synthesis | Adhesive composition |
| EP1814531B1 (de) | 2004-10-21 | 2010-06-16 | Durect Corporation | Transdermale verabreichungssysteme |
| US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
| EP1938808B1 (de) * | 2005-08-22 | 2011-01-12 | Hisamitsu Pharmaceutical Co., Inc. | Zubereitung zur topischen anwendung enthaltend tamsulosin |
| DE102006026060B4 (de) * | 2006-01-12 | 2013-01-31 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme |
| WO2007117581A2 (en) * | 2006-04-06 | 2007-10-18 | Collegium Pharmaceutical, Inc. | Stabilized transdermal bupropion preparations |
| RU2008144405A (ru) * | 2006-04-11 | 2010-05-20 | Нитибан Ко, Лтд (Jp) | Содержащий тамсулозин трансдермальный пластырь |
| US20080152592A1 (en) * | 2006-12-21 | 2008-06-26 | Bayer Healthcare Llc | Method of therapeutic drug monitoring |
| US20100210932A1 (en) * | 2007-03-20 | 2010-08-19 | Bayer Healthcare Llc | Method of analyzing an analyte |
| EP1987815A1 (de) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Im Mund-Nasen-Rachenraum verabreichbare pharmazeutische Zusammensetzungen enthaltend Dopaminagonisten zur Vorbeugung und/oder Behandlung von unruhigen Gliedmassen |
| EP2201941A1 (de) * | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
| CA2751884C (en) * | 2009-01-14 | 2018-09-25 | Corium International, Inc. | Transdermal administration of tamsulosin |
| US9072682B2 (en) | 2012-12-31 | 2015-07-07 | Mylan Inc. | Transdermal dosage form for low-melting point active agent |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61178915A (ja) * | 1985-02-04 | 1986-08-11 | Kotobuki Seiyaku Kk | 血圧降下用経皮吸収剤 |
| US4915950A (en) * | 1988-02-12 | 1990-04-10 | Cygnus Research Corporation | Printed transdermal drug delivery device |
| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5262165A (en) * | 1992-02-04 | 1993-11-16 | Schering Corporation | Transdermal nitroglycerin patch with penetration enhancers |
| GB9016056D0 (en) * | 1990-07-21 | 1990-09-05 | Chatfield Pharmaceuticals Limi | Transdermal medicine delivery devices |
| US5198223A (en) * | 1990-10-29 | 1993-03-30 | Alza Corporation | Transdermal formulations, methods and devices |
| US5633009A (en) * | 1990-11-28 | 1997-05-27 | Sano Corporation | Transdermal administration of azapirones |
| US5232702A (en) * | 1991-07-22 | 1993-08-03 | Dow Corning Corporation | Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices |
| GB9118028D0 (en) * | 1991-08-21 | 1991-10-09 | Secr Defence Brit | Improved transdrmal formulations |
| JPH06510290A (ja) * | 1991-08-27 | 1994-11-17 | シグナス,インコーポレイテッド | プラゾシンを投与するための経皮処方物 |
| FR2694495B1 (fr) * | 1992-08-05 | 1994-09-23 | Synthelabo | Préparation pharmaceutique transdermique contenant de l'alfuzosine. |
| US5503843A (en) * | 1994-04-22 | 1996-04-02 | Flora Inc. | Transdermal delivery of alpha adrenoceptor blocking agents |
| ES2172584T3 (es) * | 1994-05-18 | 2002-10-01 | Hisamitsu Pharmaceutical Co | Preparacion administrable por via percutanea para tratar trastornos de la miccion. |
| US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
-
1997
- 1997-02-28 US US08/808,211 patent/US5879701A/en not_active Expired - Lifetime
-
1998
- 1998-02-27 CA CA002252772A patent/CA2252772C/en not_active Expired - Lifetime
- 1998-02-27 PT PT98908760T patent/PT910353E/pt unknown
- 1998-02-27 EP EP98908760A patent/EP0910353B1/de not_active Expired - Lifetime
- 1998-02-27 ES ES98908760T patent/ES2226102T3/es not_active Expired - Lifetime
- 1998-02-27 DK DK98908760T patent/DK0910353T3/da active
- 1998-02-27 JP JP10537871A patent/JP2000509734A/ja not_active Ceased
- 1998-02-27 WO PCT/US1998/003832 patent/WO1998037870A1/en not_active Ceased
- 1998-02-27 AU AU66709/98A patent/AU6670998A/en not_active Abandoned
- 1998-02-27 AT AT98908760T patent/ATE271381T1/de active
- 1998-02-27 DE DE69825116T patent/DE69825116T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2252772A1 (en) | 1998-09-03 |
| JP2000509734A (ja) | 2000-08-02 |
| WO1998037870A1 (en) | 1998-09-03 |
| US5879701A (en) | 1999-03-09 |
| DK0910353T3 (da) | 2004-11-22 |
| ES2226102T3 (es) | 2005-03-16 |
| EP0910353A1 (de) | 1999-04-28 |
| DE69825116D1 (de) | 2004-08-26 |
| DE69825116T2 (de) | 2005-08-04 |
| CA2252772C (en) | 2002-04-23 |
| PT910353E (pt) | 2004-11-30 |
| EP0910353B1 (de) | 2004-07-21 |
| AU6670998A (en) | 1998-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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