ATE267799T1 - Ein verfahren zur herstellung von (2s,2'r,3'r)-2- (2,3-dicarboxycyclopropyl)-glycin - Google Patents
Ein verfahren zur herstellung von (2s,2'r,3'r)-2- (2,3-dicarboxycyclopropyl)-glycinInfo
- Publication number
- ATE267799T1 ATE267799T1 AT99915658T AT99915658T ATE267799T1 AT E267799 T1 ATE267799 T1 AT E267799T1 AT 99915658 T AT99915658 T AT 99915658T AT 99915658 T AT99915658 T AT 99915658T AT E267799 T1 ATE267799 T1 AT E267799T1
- Authority
- AT
- Austria
- Prior art keywords
- glycine
- dicarboxycyclopropyl
- producing
- mglur
- dicarboxyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98104992 | 1998-03-19 | ||
| PCT/EP1999/001803 WO1999047489A1 (en) | 1998-03-19 | 1999-03-18 | A process for the manufacture of (2s,2'r,3'r)-2-(2,3-dicarboxylcyclopropyl)-glycine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE267799T1 true ATE267799T1 (de) | 2004-06-15 |
Family
ID=8231618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99915658T ATE267799T1 (de) | 1998-03-19 | 1999-03-18 | Ein verfahren zur herstellung von (2s,2'r,3'r)-2- (2,3-dicarboxycyclopropyl)-glycin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6020525A (de) |
| EP (1) | EP1064255B1 (de) |
| JP (1) | JP3486170B2 (de) |
| AT (1) | ATE267799T1 (de) |
| AU (1) | AU749579B2 (de) |
| CA (1) | CA2323203A1 (de) |
| DE (1) | DE69917615T2 (de) |
| WO (1) | WO1999047489A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE371639T1 (de) * | 1999-12-08 | 2007-09-15 | Dsm Ip Assets Bv | Verfahren zur herstellung von enantiomeren angereicherten verbindungen |
| NL1013789C2 (nl) * | 1999-12-08 | 2001-06-12 | Dsm Nv | Werkwijze voor de bereiding van enantiomeer verrijkte verbindingen. |
| CN101768035B (zh) * | 2009-01-05 | 2013-11-27 | 浙江华海药业股份有限公司 | 一种制备以及回收芳香甲基联苯化合物的方法 |
| US9499586B2 (en) * | 2012-10-16 | 2016-11-22 | Hong Kong Baptist University | Anticancer and anti-obesity cyclic peptide agents |
| US9963485B2 (en) | 2012-10-16 | 2018-05-08 | Hong Kong Baptist University | Cycloheptapeptide agents for treatment of cancer and obesity diseases |
| WO2018068757A1 (en) * | 2016-10-14 | 2018-04-19 | Hong Kong Baptist University | Cycloheptapeptide agents for treatment of cancer and obesity diseases |
| NZ763766A (en) | 2017-03-20 | 2023-07-28 | Novo Nordisk Healthcare Ag | Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators |
| EP3852791B1 (de) | 2018-09-19 | 2024-07-03 | Novo Nordisk Health Care AG | Aktivierung von pyruvatkinase r |
| BR112021005188A2 (pt) | 2018-09-19 | 2021-06-08 | Forma Therapeutics, Inc. | tratamento de anemia falciforme com um composto de ativação de piruvato cinase r |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5186868A (en) * | 1990-04-05 | 1993-02-16 | The Regents Of The University Of California | Methods for tritium labeling |
| JP3124032B2 (ja) * | 1991-10-18 | 2001-01-15 | サントリー株式会社 | ２−（２，３−ジカルボキシシクロプロピル）グリシン及びその製造法 |
-
1999
- 1999-02-23 US US09/256,047 patent/US6020525A/en not_active Expired - Fee Related
- 1999-03-18 DE DE69917615T patent/DE69917615T2/de not_active Expired - Fee Related
- 1999-03-18 CA CA002323203A patent/CA2323203A1/en not_active Abandoned
- 1999-03-18 AU AU34149/99A patent/AU749579B2/en not_active Ceased
- 1999-03-18 AT AT99915658T patent/ATE267799T1/de not_active IP Right Cessation
- 1999-03-18 JP JP2000536686A patent/JP3486170B2/ja not_active Expired - Fee Related
- 1999-03-18 EP EP99915658A patent/EP1064255B1/de not_active Expired - Lifetime
- 1999-03-18 WO PCT/EP1999/001803 patent/WO1999047489A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US6020525A (en) | 2000-02-01 |
| AU3414999A (en) | 1999-10-11 |
| DE69917615D1 (de) | 2004-07-01 |
| DE69917615T2 (de) | 2005-06-16 |
| JP3486170B2 (ja) | 2004-01-13 |
| JP2002506846A (ja) | 2002-03-05 |
| EP1064255A1 (de) | 2001-01-03 |
| AU749579B2 (en) | 2002-06-27 |
| EP1064255B1 (de) | 2004-05-26 |
| WO1999047489A1 (en) | 1999-09-23 |
| CA2323203A1 (en) | 1999-09-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59108707D1 (de) | Verfahren zur Herstellung von Oxetanonen | |
| ATE38661T1 (de) | Zwischenprodukt und verfahren zu dessen herstellung. | |
| ATE266030T1 (de) | 1,4,7,10-tetraazabicyclo(8.2.2)tetradecan-2-on, verfahren zu ihrer herstellung und ihrer verwendung für die herstellung von tetraazamacrocyclen | |
| DE59609824D1 (de) | Verfahren zur herstellung von substituierten arylmilchsäure-haltigen cyclodepsipeptiden mit 24 ringatomen | |
| ATE224395T1 (de) | Verfahren zur herstellung von 2-substituierten 1- (tetrazol-5-yl)benzenverbindungen durch ortho- metallierung | |
| ATE267799T1 (de) | Ein verfahren zur herstellung von (2s,2'r,3'r)-2- (2,3-dicarboxycyclopropyl)-glycin | |
| ATE236139T1 (de) | Verfahren zur herstellung von 2-chlor-5- chlomethyl-thiazol-derivaten | |
| AR006058A1 (es) | Procedimientos para preparar compuestos de dicianoacetato y de 1,2-pirazol-5-amino-3-substituido | |
| ATE407127T1 (de) | Verfahren zur herstellung von beraprost und dessen salzen | |
| ATE457972T1 (de) | Verfahren zur herstellung von 7-amino-syn-3,5- dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung | |
| HUP0104193A2 (hu) | Javított eljárás új antidiabetikus hatású vegyületek előállítására | |
| DE69635057D1 (de) | Verfahren zur herstellung von campothecinderivate | |
| ATE271043T1 (de) | Verfahren zur herstellung von 2-chlor-5- chloromethyl-thiazol | |
| DE60015563D1 (de) | Verfahren zur herstellung von benzoperhydroisoindolen | |
| DE58900098D1 (de) | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung. | |
| ATE353937T1 (de) | Verfahren zur synthese einer oxonolverbindung | |
| ATE282594T1 (de) | Verfahren zur herstellung von (+)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidin | |
| ATE213734T1 (de) | Verfahren zur herstellung von 1,3- disubstituierten 2-nitroguanidinen | |
| DE69518252D1 (de) | Verfahren zur herstellung von 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalin-derivaten | |
| DE69513408D1 (de) | Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl-lipopeptiden | |
| DE59907056D1 (de) | Verfahren zur herstellung von cyclen | |
| DE60011463D1 (de) | Verfahren zur herstellung von 24(s)-hydroxyvitamin d2 | |
| ATE159246T1 (de) | Verfahren zur herstellung von (s)-vinyl- und (s)- allenyl-gaba | |
| ATE200776T1 (de) | Verfahren zur herstellung von 2,4,5-tribrompyrrol-3-carbonitril | |
| BR0113944A (pt) | Processo para a produção de compostos quirais |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1064255 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |