ATE264692T1 - Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämie - Google Patents
Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämieInfo
- Publication number
- ATE264692T1 ATE264692T1 AT97940183T AT97940183T ATE264692T1 AT E264692 T1 ATE264692 T1 AT E264692T1 AT 97940183 T AT97940183 T AT 97940183T AT 97940183 T AT97940183 T AT 97940183T AT E264692 T1 ATE264692 T1 AT E264692T1
- Authority
- AT
- Austria
- Prior art keywords
- caughters
- reactive oxygen
- synthase inhibitors
- oxygen forms
- treat ischemia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9610875A FR2753098B1 (fr) | 1996-09-06 | 1996-09-06 | Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene |
PCT/FR1997/001567 WO1998009653A1 (fr) | 1996-09-06 | 1997-09-05 | Association inhibiteurs de no synthase et piegeurs des formes reactives de l'oxygene |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE264692T1 true ATE264692T1 (de) | 2004-05-15 |
Family
ID=9495505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97940183T ATE264692T1 (de) | 1996-09-06 | 1997-09-05 | Verwendung von no synthase hemmern und fängern von reaktiven sauerstoffsformen zur behandlung von ischämie |
Country Status (14)
Country | Link |
---|---|
US (1) | US6297281B1 (de) |
EP (1) | EP0939654B1 (de) |
JP (1) | JP2000517336A (de) |
AT (1) | ATE264692T1 (de) |
AU (1) | AU734296B2 (de) |
CA (1) | CA2264901C (de) |
DE (1) | DE69728782T2 (de) |
ES (1) | ES2221066T3 (de) |
FR (1) | FR2753098B1 (de) |
IL (1) | IL128801A (de) |
NO (1) | NO991100L (de) |
NZ (1) | NZ334597A (de) |
RU (1) | RU2174844C2 (de) |
WO (1) | WO1998009653A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030017998A1 (en) * | 1997-05-16 | 2003-01-23 | Snow Alan D. | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
EP1068868A3 (de) * | 1997-07-08 | 2001-01-31 | Rath, Matthias, Dr. med. | Synergistischer Zusammensetzung, der Ascorbat und Lysin für Zustände enthält zur Behandlung extrazellularer Matrixdegeneration |
WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
DE69911212T2 (de) * | 1998-07-10 | 2004-07-15 | Duke University | Anwendung der hemoproteine in der therapie |
FR2783519B1 (fr) * | 1998-09-23 | 2003-01-24 | Sod Conseils Rech Applic | Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
GB9827393D0 (en) * | 1998-12-11 | 1999-02-03 | Univ London | Treatment of erectile dysfunction in diabetes patients |
FR2787447B1 (fr) * | 1998-12-18 | 2001-03-23 | Centre Nat Rech Scient | Nouveaux derives de melatonine et medicament comprenant de tels derives |
EP1013272A1 (de) * | 1998-12-23 | 2000-06-28 | Biomedical Primate Research Centre (BPRC) | Beeinflussung der Aktivität eines Stickoxidradikalherstellungsweges zur Behandlung von mit freien Sauerstoffradikalen verbundenen Krankheiten |
US6075045A (en) * | 1999-04-28 | 2000-06-13 | Ajinomoto Co., Inc. | Method of treating paralysis of the extremities caused by cerebral infarction |
DE19962267A1 (de) * | 1999-12-23 | 2001-06-28 | Beiersdorf Ag | Verwendung von Wirkstoffkombinationen aus einem oder mehreren NO-Synthasehemmern und einer oder mehreren Ascorbylverbindungen zur Stärkung der Barrierefunktion der Haut |
EP1808169B8 (de) * | 1999-12-30 | 2012-07-04 | Proteotech Inc. | Polyhydroxylierte aromatische Verbindungen zur Behandlung von Amyloidose und $g(a)-Synuklein-Fibrillen-Erkrankungen |
US20010047032A1 (en) * | 1999-12-30 | 2001-11-29 | Castillo Gerardo M. | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases |
DE10000840A1 (de) * | 2000-01-12 | 2001-07-19 | Beiersdorf Ag | Verwendung eines oder mehrerer NO-Synthasehemmer |
AU2001274858A1 (en) * | 2000-06-08 | 2001-12-17 | Board Of Regents, The University Of Texas System | Heterocycle derivatives and methods of use for treating anthrax infection |
WO2001095897A1 (en) * | 2000-06-15 | 2001-12-20 | University Of Kentucky Research Foundation | Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders |
DK1315505T3 (da) * | 2000-09-05 | 2008-03-03 | Meditor Pharmaceuticals Ltd | Farmaceutiske præparater mod hovedpine, migræne, kvalme og emesis |
US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
US7034054B2 (en) * | 2000-12-15 | 2006-04-25 | Galileo Pharmaceuticals, Inc. | Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols |
US6974833B2 (en) | 2001-01-16 | 2005-12-13 | Matthias Rath | Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration |
DE10111050A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigenOrganismus ihre Wirkung entfaltet, zur Herstellung von kosmetischewn oder dermatologischen Zubereitungen zur Behandlung und/oder Prophylaxe unerwünschter Hautpigmentierung |
DE10111054A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut |
DE10111049A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen, zur Prophylaxe und Behandlung von entzündlichen Hautzuständen und/oder zum Hautschutz bei empfindlich determinierter trockener Haut |
DE10111052A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese |
WO2003039540A2 (en) * | 2001-11-09 | 2003-05-15 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
DE10219644A1 (de) * | 2002-05-02 | 2003-11-20 | Johannes Wohlrab | Verwendung vom Agmatin zur topischen Applikation |
ES2447417T3 (es) * | 2002-05-31 | 2014-03-12 | Proteotech, Inc. | Compuestos, composiciones y métodos para el tratamiento de amiloidosis y sinucleinopatías tales como la enfermedad de Alzheimer, la diabetes de tipo 2 y la enfermedad de Parkinson |
GB0214147D0 (en) * | 2002-06-19 | 2002-07-31 | Glaxo Group Ltd | Formulations |
EP1554270A2 (de) * | 2002-10-11 | 2005-07-20 | Proteotech, Inc. | Isolierung, reinigung und synthese von procyanidin b2 sowie seine verwendung |
US20050234026A1 (en) * | 2003-11-10 | 2005-10-20 | Weinberg Joe B | Method and agent for inducing apoptosis/cell death in leukemia cells |
US20090186929A1 (en) * | 2003-11-10 | 2009-07-23 | U.S. Department Of Veterans Affairs | Method and agent for inducing apoptosis/cell death in leukemia cells |
PL380887A1 (pl) | 2003-12-29 | 2007-04-02 | Sepracor Inc. | Pirolowe i pirazolowe inhibitory DAAO |
EP1896035B1 (de) | 2004-06-16 | 2014-10-15 | Jack L. Arbiser | Carbazol-Formulierungen zur Behandlung von Psoriasis und Angiogenese |
EP1871883A1 (de) | 2005-03-02 | 2008-01-02 | Metanomics GmbH | Verfahren zur produktion von feinchemikalien |
US8283327B2 (en) | 2005-03-19 | 2012-10-09 | Kneller Bruce W | Palatinose for enhancing dietary supplement and pharmaceutical delivery |
HUE033304T2 (en) | 2005-06-01 | 2017-11-28 | Bioelectron Tech Corp | Redoxactive therapeutic agents for the treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
EP1902710A4 (de) * | 2005-07-04 | 2009-12-02 | Univ Tokyo Medical & Dental | Pharmazeutische zusammensetzung und getränkezusammensetzung mit l-arginin |
JP5374162B2 (ja) | 2006-02-22 | 2013-12-25 | エジソン ファーマシューティカルズ, インコーポレイテッド | ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節 |
US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
BRPI0918139A2 (pt) | 2008-09-10 | 2015-12-01 | Edison Pharmaceuticals Inc | composição, alimento medicinal ou funcional, suplemento alimentar ou dietético para tratamento de distúrbios de desenvolvimento pervasivos com terapêuticos redox-ativos e uso |
EP2273273A1 (de) | 2009-07-11 | 2011-01-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | Inhibitoren der Nitrierung von Amyloid-ß-Peptiden und ihre Verwendung bei der Diagnose und Behandlung von Morbus Alzheimer |
PT2470168T (pt) * | 2009-08-26 | 2018-03-28 | Bioelectron Tech Corp | Métodos para a prevenção e o tratamento de isquemia cerebral |
KR20140097132A (ko) * | 2011-11-22 | 2014-08-06 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 허혈성 손상을 치료하기 위한 시스테아민 및/또는 시스타민 |
UA119032C2 (uk) * | 2012-10-02 | 2019-04-25 | Женеро Са | Фармацевтична композиція для лікування блокади ремієлінізації при захворюваннях, які пов'язані з експресією білка оболонки herv-w |
CN113024369A (zh) | 2015-12-17 | 2021-06-25 | Ptc医疗公司 | 用于治疗氧化应急障碍的化合物 |
-
1996
- 1996-09-06 FR FR9610875A patent/FR2753098B1/fr not_active Expired - Fee Related
-
1997
- 1997-09-05 ES ES97940183T patent/ES2221066T3/es not_active Expired - Lifetime
- 1997-09-05 EP EP97940183A patent/EP0939654B1/de not_active Expired - Lifetime
- 1997-09-05 RU RU99106792/14A patent/RU2174844C2/ru not_active IP Right Cessation
- 1997-09-05 AT AT97940183T patent/ATE264692T1/de not_active IP Right Cessation
- 1997-09-05 NZ NZ334597A patent/NZ334597A/xx unknown
- 1997-09-05 US US09/254,254 patent/US6297281B1/en not_active Expired - Fee Related
- 1997-09-05 JP JP10512314A patent/JP2000517336A/ja not_active Ceased
- 1997-09-05 AU AU42111/97A patent/AU734296B2/en not_active Ceased
- 1997-09-05 WO PCT/FR1997/001567 patent/WO1998009653A1/fr active IP Right Grant
- 1997-09-05 CA CA002264901A patent/CA2264901C/fr not_active Expired - Fee Related
- 1997-09-05 DE DE69728782T patent/DE69728782T2/de not_active Expired - Fee Related
- 1997-09-05 IL IL12880197A patent/IL128801A/xx not_active IP Right Cessation
-
1999
- 1999-03-05 NO NO991100A patent/NO991100L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69728782T2 (de) | 2005-04-28 |
NZ334597A (en) | 2000-10-27 |
EP0939654A1 (de) | 1999-09-08 |
US6297281B1 (en) | 2001-10-02 |
FR2753098B1 (fr) | 1998-11-27 |
IL128801A (en) | 2005-05-17 |
NO991100L (no) | 1999-05-05 |
NO991100D0 (no) | 1999-03-05 |
CA2264901A1 (fr) | 1998-03-12 |
IL128801A0 (en) | 2000-01-31 |
EP0939654B1 (de) | 2004-04-21 |
AU734296B2 (en) | 2001-06-07 |
ES2221066T3 (es) | 2004-12-16 |
DE69728782D1 (de) | 2004-05-27 |
AU4211197A (en) | 1998-03-26 |
WO1998009653A1 (fr) | 1998-03-12 |
JP2000517336A (ja) | 2000-12-26 |
RU2174844C2 (ru) | 2001-10-20 |
FR2753098A1 (fr) | 1998-03-13 |
CA2264901C (fr) | 2006-01-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |