ATE257516T1 - Nukleotidsequenzen, die für ein protein mit ureaseaktivität kodieren - Google Patents

Nukleotidsequenzen, die für ein protein mit ureaseaktivität kodieren

Info

Publication number
ATE257516T1
ATE257516T1 AT94110776T AT94110776T ATE257516T1 AT E257516 T1 ATE257516 T1 AT E257516T1 AT 94110776 T AT94110776 T AT 94110776T AT 94110776 T AT94110776 T AT 94110776T AT E257516 T1 ATE257516 T1 AT E257516T1
Authority
AT
Austria
Prior art keywords
protein
nucleotide sequences
urease activity
sequences coding
urease
Prior art date
Application number
AT94110776T
Other languages
English (en)
Inventor
Agnes Labigne
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE257516T1 publication Critical patent/ATE257516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT94110776T 1988-10-06 1989-10-06 Nukleotidsequenzen, die für ein protein mit ureaseaktivität kodieren ATE257516T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8813135A FR2637612B1 (fr) 1988-10-06 1988-10-06 Sequences de nucleotides codant pour une proteine a activite ureasique

Publications (1)

Publication Number Publication Date
ATE257516T1 true ATE257516T1 (de) 2004-01-15

Family

ID=9370758

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94110776T ATE257516T1 (de) 1988-10-06 1989-10-06 Nukleotidsequenzen, die für ein protein mit ureaseaktivität kodieren
AT89402764T ATE118821T1 (de) 1988-10-06 1989-10-06 Nukleotidesequenzen, die ein protein mit ureareaktivität kodieren.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89402764T ATE118821T1 (de) 1988-10-06 1989-10-06 Nukleotidesequenzen, die ein protein mit ureareaktivität kodieren.

Country Status (9)

Country Link
US (5) US5695931A (de)
EP (2) EP0649906B1 (de)
JP (3) JP2628767B2 (de)
AT (2) ATE257516T1 (de)
DE (2) DE68921287T2 (de)
ES (2) ES2214479T3 (de)
FR (1) FR2637612B1 (de)
SG (1) SG49097A1 (de)
WO (1) WO1990004030A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2637612B1 (fr) * 1988-10-06 1993-09-10 Pasteur Institut Sequences de nucleotides codant pour une proteine a activite ureasique
GB8928625D0 (en) * 1989-12-19 1990-02-21 3I Res Expl Ltd H.pylori dna probes
IE76730B1 (en) * 1990-07-30 1997-11-05 Abbott Laboraties Method and product for the treatment of gastric disease
JPH04169539A (ja) * 1990-11-01 1992-06-17 Imuno Japan:Kk 消化器疾患治療・予防剤およびその製造方法
FR2682122B1 (fr) 1991-10-03 1995-06-09 Pasteur Institut Nouveaux genes d'helicobacter pylori. leur utilisation pour la preparation de souches recombinantes de h. pylori.
US6130059A (en) * 1992-03-02 2000-10-10 Covacci; Antonello Helicobacter pylori proteins useful for vaccines and diagnostics
US5928865A (en) * 1992-03-02 1999-07-27 Chiron S.P.A. Compositions comprising isolated Helicobacter pylori CagI polynucleotides and method of preparation thereof
US7141244B1 (en) 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
IT1262895B (it) * 1992-03-02 1996-07-22 Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico.
AU3630093A (en) * 1992-03-02 1993-10-05 Biocine S.P.A. Helicobacter pylori proteins useful for vaccines and diagnostics
MX9301706A (es) * 1992-04-13 1994-05-31 Oravax Inc Composicion de vacuna para el tratamiento de la infeccion por helicobacter.
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
AU6718894A (en) * 1993-05-14 1994-12-12 Voon Loong Chan Hippuricase gene
JPH08509873A (ja) * 1993-05-19 1996-10-22 アンスティテュ・パストゥール ヘリコバクター感染に対する免疫組成物、該組成物に用いられるポリペプチドおよび該ポリペプチドをコードする核酸配列
US6258359B1 (en) 1993-05-19 2001-07-10 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
GB9313437D0 (en) * 1993-06-30 1993-08-11 Smith Andrew W Pathogenicity sequences in helicobacter pylori
EP0716613B1 (de) * 1993-07-27 2003-07-09 Csl Limited Behandlung eines durch helicobakter verursachten gastroduodenalen krankheit
US6406703B1 (en) 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
FR2719998B1 (fr) * 1994-04-08 1996-09-27 Pasteur Merieux Serums Vacc Composition immunisante anti-hélicobacter pylori à base de catalase.
AUPM612494A0 (en) * 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
GB2290710B (en) * 1994-06-29 1998-03-25 Reckitt & Colmann Prod Ltd Protease from helicobacter pylori for use in vaccines/therapeutic compositions
US6468765B1 (en) 1995-04-21 2002-10-22 Human Genome Sciences, Inc. Selected Haemophilus influenzae Rd polynucleotides and polypeptides
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
EP0909323B1 (de) 1996-01-04 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Bakterioferritin aus helicobacter pylori
AU2304097A (en) * 1996-04-05 1997-10-29 Kieta Holding S.A. Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases
US6248551B1 (en) * 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
JP3430853B2 (ja) * 1997-04-11 2003-07-28 株式会社ゲン・コーポレーション 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤
AU770498B2 (en) 1998-06-19 2004-02-26 Merieux Oravax LT and CT in parenteral immunization methods against helicobacter infection
US6190667B1 (en) 1998-06-30 2001-02-20 Institut Pasteur Methods of inhibiting Helicobacter pylori
TWI237695B (en) * 1999-12-14 2005-08-11 Joy Biomedical Corp Helicobacter pylori antigens in blood
US7597895B2 (en) * 2001-02-20 2009-10-06 The Governing Council Of The University Of Toronto Signal peptides, nucleic acid molecules and methods for treatment of caries
US7556807B2 (en) 2001-02-20 2009-07-07 Kane Biotech, Inc. Signal peptides, nucleic acid molecules and methods for treatment of caries
US7211250B2 (en) 2002-07-18 2007-05-01 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
CA2758687A1 (en) * 2008-11-14 2010-05-20 Gen-Probe Incorporated Compositions, kits and methods for detection of campylobacter nucleic acid
AU2014252666B2 (en) 2013-04-08 2017-02-02 Helix Biopharma Corp. Use of antibody-urease conjugates for diagnostic and therapeutic purposes
US20160032268A1 (en) * 2014-07-30 2016-02-04 Medtronic, Inc. Urease purification from jack beans or other organisms
EP3261678B8 (de) 2015-01-23 2021-03-17 Helix Biopharma Corp. Antikörper-urease-konjugate für therapeutische zwecke

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785086A (en) * 1985-01-17 1988-11-15 Integrated Genetics, Inc. Test for Campylobacter
DK171161B1 (da) * 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
CA1274757A (en) * 1985-05-17 1990-10-02 Barry James Marshall Compositions and methods for the detection of urease for the diagnosis of campylobacter pyloridis infection
EP0233261A1 (de) * 1985-08-16 1987-08-26 WINN, Gregory, Murray Monoklonale antikörper, reaktiv gegen campylobacter pylorides
US4837017A (en) * 1987-03-12 1989-06-06 Leveen Harry H Urease antigen product and process
US4882271A (en) * 1988-03-10 1989-11-21 Baylor College Of Medicine Process for preparation of high molecular weight cell-associated protein of campylobacter pylori and use for serological detection of campylobacter pylori infection
AU3054789A (en) * 1988-03-23 1989-10-16 Julie Claire Dent Detection of campylobacter pylori urease antibodies and reagent therefor
FR2637612B1 (fr) * 1988-10-06 1993-09-10 Pasteur Institut Sequences de nucleotides codant pour une proteine a activite ureasique
KR19990008155A (ko) * 1995-04-28 1999-01-25 랜스 고든 다가, 재조합 우레아제 백신

Also Published As

Publication number Publication date
DE68921287T2 (de) 1995-06-22
EP0367644B1 (de) 1995-02-22
US5695931A (en) 1997-12-09
DE68929510D1 (de) 2004-02-12
JP2974966B2 (ja) 1999-11-10
US5837472A (en) 1998-11-17
ATE118821T1 (de) 1995-03-15
US5811237A (en) 1998-09-22
DE68921287D1 (de) 1995-03-30
JPH03501928A (ja) 1991-05-09
SG49097A1 (en) 1998-05-18
US5849295A (en) 1998-12-15
EP0649906A1 (de) 1995-04-26
FR2637612B1 (fr) 1993-09-10
EP0367644A1 (de) 1990-05-09
JP3375470B2 (ja) 2003-02-10
DE68929510T2 (de) 2004-11-18
JP2628767B2 (ja) 1997-07-09
JPH08196283A (ja) 1996-08-06
US6146634A (en) 2000-11-14
WO1990004030A1 (fr) 1990-04-19
ES2214479T3 (es) 2004-09-16
EP0649906B1 (de) 2004-01-07
FR2637612A1 (fr) 1990-04-13
ES2068907T3 (es) 1995-05-01
JPH09117286A (ja) 1997-05-06

Similar Documents

Publication Publication Date Title
DE68929510D1 (de) Nukleotidsequenzen, die für ein Protein mit Ureaseaktivität kodieren
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
HUT43630A (en) Mammalian interleukine-4 and process for producing it
HUT63652A (en) Process for producing cd44 surface protein variants, dna sequences encoding them and antibodies against them, as well as their application in diagnosis and therapy
PT92603A (pt) Processo de producao de factor de crescimento transformante, quimerico,beta
DK0666914T3 (da) Hidtil ukendt P-selectin-ligandprotein
JPS6420094A (en) Production and purification of protein fused to binding protein
DE69839178D1 (de) Gene, die für proteine mit transglykolysierungsaktivität kodieren.
PT86276A (en) Method for the production of hybrid proteins
WO1995030001A3 (en) Novel p-selectin ligand protein
ZA916171B (en) Protein structure of the plant toxin gelonin
DK38889D0 (da) Onkogen-indkodet polypeptid med vaekstfaktoraktivitet
DE3856392D1 (de) Klonierung von Malaria-spezifischen DNA-Sequenzen:Isolierung des Gens für das 140 kd Protein
DK0828004T3 (da) Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær
SE8403929D0 (sv) Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase
NZ235411A (en) Antibodies produced to highly conserved amino acid sequences of insulin
ES2133236A1 (es) Gen quimerico formado por las secuencias de dna que codifican los determinantes antigenicos de cuatro proteinas de l. infantum, aplicable para el diagnostico serologico de leishmaniosis canina y proteina obtenida.
ATE110112T1 (de) Verfahren und systeme zur herstellung von hiv- antigenen.
ATE107694T1 (de) Für a.nidulans-isopenicillin-n-synthetase codierende dns, deren verwendung und dafür codierende vektoren.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0649906

Country of ref document: EP

EELA Cancelled due to lapse of time