ATE257470T1 - Tricyclische benz(e)isoindole und benz(h)isochinoline - Google Patents

Tricyclische benz(e)isoindole und benz(h)isochinoline

Info

Publication number
ATE257470T1
ATE257470T1 AT98902982T AT98902982T ATE257470T1 AT E257470 T1 ATE257470 T1 AT E257470T1 AT 98902982 T AT98902982 T AT 98902982T AT 98902982 T AT98902982 T AT 98902982T AT E257470 T1 ATE257470 T1 AT E257470T1
Authority
AT
Austria
Prior art keywords
disorders
benz
isoindoles
stroke
mental
Prior art date
Application number
AT98902982T
Other languages
English (en)
Inventor
Michael Boes
Heinz Stadler
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE257470T1 publication Critical patent/ATE257470T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
AT98902982T 1997-01-08 1998-01-07 Tricyclische benz(e)isoindole und benz(h)isochinoline ATE257470T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97100172 1997-01-08
PCT/EP1998/000043 WO1998030546A1 (en) 1997-01-08 1998-01-07 TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES

Publications (1)

Publication Number Publication Date
ATE257470T1 true ATE257470T1 (de) 2004-01-15

Family

ID=26145159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98902982T ATE257470T1 (de) 1997-01-08 1998-01-07 Tricyclische benz(e)isoindole und benz(h)isochinoline

Country Status (9)

Country Link
EP (1) EP0958285B1 (de)
JP (1) JP3297058B2 (de)
AT (1) ATE257470T1 (de)
AU (1) AU742735B2 (de)
BR (1) BR9807100A (de)
CA (1) CA2276098C (de)
DE (1) DE69820989T2 (de)
DK (1) DK0958285T3 (de)
WO (1) WO1998030546A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269484C (zh) 1998-09-18 2006-08-16 艾尔科实验室公司 用于治疗青光眼的5－羟色胺激活性激动剂
JP2005506280A (ja) 2000-12-20 2005-03-03 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー アリールおよびアミノアリール置換セロトニン受容体アゴニストおよびアンタゴニストリガンド
JP2004115510A (ja) * 2002-09-05 2004-04-15 Toray Fine Chemicals Co Ltd ピペラジン誘導体の製造方法
EP2400300A1 (de) 2004-08-25 2011-12-28 Takeda Pharmaceutical Company Limited Screeningverfahren von Mitteln zur Prävention/Behandlung von stressbedingter Harninkontinenz
ATE507832T1 (de) * 2004-09-03 2011-05-15 Athersys Inc Trizyklische heteroaryl-piperazine, pyrrolidine und azetidine als serotonin-rezeptor-modulatoren
EP2727585A1 (de) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo Screening-Methode
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (en) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Hydroxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
CN100402534C (zh) * 2006-11-09 2008-07-16 东南大学 一种三环类化合物及其在制药中的应用
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
EP3733204A4 (de) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited Therapeutikum für belastungsinkontinenz und stuhlinkontinenz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH504438A (de) * 1968-05-27 1971-03-15 Sandoz Ag Verfahren zur Herstellung von 1,2,3,4,4a,5,6,10b-Octahydrobenz(h)isochinolin-6-on
US4678791A (en) * 1985-05-07 1987-07-07 Pennwalt Corporation 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression
US5180733A (en) * 1990-03-30 1993-01-19 Abbott Laboratories Biogenic amine uptake inhibitors

Also Published As

Publication number Publication date
DE69820989T2 (de) 2004-12-09
CA2276098C (en) 2007-05-08
AU742735B2 (en) 2002-01-10
EP0958285B1 (de) 2004-01-07
BR9807100A (pt) 2000-04-25
JP2000507965A (ja) 2000-06-27
WO1998030546A1 (en) 1998-07-16
CA2276098A1 (en) 1998-07-16
EP0958285A1 (de) 1999-11-24
DE69820989D1 (de) 2004-02-12
JP3297058B2 (ja) 2002-07-02
DK0958285T3 (da) 2004-05-17
AU5986698A (en) 1998-08-03

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