ATE245992T1 - Progestagen-freie formulierungen von gnrh und estrogen zur behandlung von benignen gynäkologischen störungen - Google Patents

Progestagen-freie formulierungen von gnrh und estrogen zur behandlung von benignen gynäkologischen störungen

Info

Publication number
ATE245992T1
ATE245992T1 AT94917349T AT94917349T ATE245992T1 AT E245992 T1 ATE245992 T1 AT E245992T1 AT 94917349 T AT94917349 T AT 94917349T AT 94917349 T AT94917349 T AT 94917349T AT E245992 T1 ATE245992 T1 AT E245992T1
Authority
AT
Austria
Prior art keywords
benigan
progestagen
gnrh
estrogen
treatment
Prior art date
Application number
AT94917349T
Other languages
English (en)
Inventor
Malcolm Cecil Pike
Darcy Vernon Spicer
Original Assignee
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Southern California filed Critical Univ Southern California
Application granted granted Critical
Publication of ATE245992T1 publication Critical patent/ATE245992T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/14—Topical contraceptives and spermacides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
AT94917349T 1993-05-17 1994-05-12 Progestagen-freie formulierungen von gnrh und estrogen zur behandlung von benignen gynäkologischen störungen ATE245992T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/062,883 US5340585A (en) 1991-04-12 1993-05-17 Method and formulations for use in treating benign gynecological disorders
PCT/US1994/005222 WO1994026207A1 (en) 1993-05-17 1994-05-12 Methods and formulations for use in treating benign gynecological disorders

Publications (1)

Publication Number Publication Date
ATE245992T1 true ATE245992T1 (de) 2003-08-15

Family

ID=22045464

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94917349T ATE245992T1 (de) 1993-05-17 1994-05-12 Progestagen-freie formulierungen von gnrh und estrogen zur behandlung von benignen gynäkologischen störungen

Country Status (10)

Country Link
US (1) US5340585A (de)
EP (1) EP0748190B1 (de)
AT (1) ATE245992T1 (de)
CA (1) CA2162261A1 (de)
DE (1) DE69432990T2 (de)
DK (1) DK0748190T3 (de)
ES (1) ES2204917T3 (de)
NO (1) NO321502B1 (de)
PT (1) PT748190E (de)
WO (1) WO1994026207A1 (de)

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US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
CN1216636C (zh) 1996-08-30 2005-08-31 派普泰克有限公司 肽缓释组合物
US5993856A (en) * 1997-01-24 1999-11-30 Femmepharma Pharmaceutical preparations and methods for their administration
US6416778B1 (en) 1997-01-24 2002-07-09 Femmepharma Pharmaceutical preparations and methods for their regional administration
JPH10279499A (ja) * 1997-04-04 1998-10-20 Takeda Chem Ind Ltd 子宮粘膜適用製剤
CN1184957C (zh) * 1997-05-07 2005-01-19 盖伦(化学制品)有限公司 用于给药睾酮和睾酮前体的阴道内给药装置
DE19815060A1 (de) * 1998-04-03 1999-10-14 Jenapharm Gmbh Pharmazeutische Präparate zur Therapie von Nebenwirkungen während und/oder nach einer GnRHa-Therapie
US20040167111A1 (en) * 1998-04-15 2004-08-26 Michael Oettel Pharmaceutical preparations for treating side effects during and/or after GnRHa therapy
US6217844B1 (en) * 1998-04-27 2001-04-17 Praecis Pharmaceuticals, Inc. Methods for detecting lesions in dense breast tissue using LHRH antagonists
US6265393B1 (en) 1998-08-07 2001-07-24 Heinrichs William Leroy Prevention of endometriosis signs or symptons
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
EP1187618A1 (de) * 1999-06-04 2002-03-20 The General Hospital Corporation PHARMAZEUTISCHE FORMüLIERUNGEN ZUR BEHANDLUNG VON FRAUEN IN DER POSTMENOPAUSE UND PERIMENOPAUSE UND DEREN ANWENDUNG
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
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WO2002036144A1 (en) * 2000-10-30 2002-05-10 University Of Zurich Gnrh analogues for treatment of urinary incontinence
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ATE350041T1 (de) * 2001-05-18 2007-01-15 Pantarhei Bioscience Bv Pharmaceutishe zusammensetzung für die hormonersatztherapie
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EP1390041B1 (de) * 2001-05-23 2009-11-25 Pantarhei Bioscience B.V. Tetrahydroxylierte estrogen enthaltendes arzneistoffverabreichungssystem zur verwendung in hormonalen kontrazeption
DE60223795T2 (de) * 2001-05-23 2008-11-27 Pantarhei Bioscience B.V. Tetrahydroxyliertes Östrogen enthaltendes Arzneistoffverabreichungssystem zur Verwendung in der hormonalen Kontrazeption
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AU2003274941A1 (en) * 2002-06-11 2003-12-22 Pantarhei Bioscience B.V. A method of treating human skin and a skin care composition for use in such a method
SI1511496T1 (sl) * 2002-06-11 2007-04-30 Pantarhei Bioscience Bv Metoda zdravljenja ali prevencije imunsko mediiranih motenj in farmacevtska formulacija za njeno uporabo
CA2492287C (en) * 2002-07-12 2011-12-13 Pantarhei Bioscience B.V. Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
US6958142B2 (en) * 2002-08-02 2005-10-25 Balance Pharmaceuticals, Inc. Nasal spray formulation and method
US6960337B2 (en) * 2002-08-02 2005-11-01 Balance Pharmaceuticals, Inc. Methods and compositions for treating benign gynecological disorders
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US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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Also Published As

Publication number Publication date
DE69432990D1 (de) 2003-09-04
US5340585A (en) 1994-08-23
EP0748190A1 (de) 1996-12-18
NO954611D0 (no) 1995-11-15
EP0748190B1 (de) 2003-07-30
PT748190E (pt) 2003-12-31
DE69432990T2 (de) 2004-04-22
EP0748190A4 (de) 1998-06-10
ES2204917T3 (es) 2004-05-01
DK0748190T3 (da) 2003-10-27
CA2162261A1 (en) 1994-11-24
NO321502B1 (no) 2006-05-15
WO1994026207A1 (en) 1994-11-24
NO954611L (no) 1996-01-16

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