ATE245814T1 - Verffahren zum überwachen der befolgung einer vorgeschriebenen medikation durch einen patienten - Google Patents
Verffahren zum überwachen der befolgung einer vorgeschriebenen medikation durch einen patientenInfo
- Publication number
- ATE245814T1 ATE245814T1 AT94931983T AT94931983T ATE245814T1 AT E245814 T1 ATE245814 T1 AT E245814T1 AT 94931983 T AT94931983 T AT 94931983T AT 94931983 T AT94931983 T AT 94931983T AT E245814 T1 ATE245814 T1 AT E245814T1
- Authority
- AT
- Austria
- Prior art keywords
- urine
- medication
- patient
- medication concentration
- concentration
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 14
- 239000003814 drug Substances 0.000 title abstract 14
- 238000000034 method Methods 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 210000002700 urine Anatomy 0.000 abstract 12
- 230000005484 gravity Effects 0.000 abstract 3
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9486—Analgesics, e.g. opiates, aspirine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/493—Physical analysis of biological material of liquid biological material urine
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/901—Drugs of abuse, e.g. narcotics, amphetamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Primary Health Care (AREA)
- Food Science & Technology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/145,821 US6124136A (en) | 1993-11-02 | 1993-11-02 | Method of monitoring compliance with methadone treatment program |
| US08/248,102 US5547878A (en) | 1993-11-02 | 1994-05-24 | Method of monitoring patient compliance with medications prescriptions |
| PCT/US1994/012119 WO1995012812A1 (en) | 1993-11-02 | 1994-10-19 | Method of monitoring patient compliance with medications prescriptions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245814T1 true ATE245814T1 (de) | 2003-08-15 |
Family
ID=26843316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94931983T ATE245814T1 (de) | 1993-11-02 | 1994-10-19 | Verffahren zum überwachen der befolgung einer vorgeschriebenen medikation durch einen patienten |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5652146A (de) |
| EP (1) | EP0748444B1 (de) |
| JP (1) | JP4389005B2 (de) |
| AT (1) | ATE245814T1 (de) |
| AU (1) | AU698403B2 (de) |
| CA (1) | CA2175584C (de) |
| DE (1) | DE69432976D1 (de) |
| WO (1) | WO1995012812A1 (de) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5955370A (en) * | 1993-11-02 | 1999-09-21 | U.D. Testing, Inc. | Urine adulteration test method |
| US5602038A (en) * | 1994-07-25 | 1997-02-11 | Private Clinic Laboratories, Inc. | Method of determining renal clearances |
| JP3592822B2 (ja) * | 1996-01-23 | 2004-11-24 | 株式会社いかがく | 採取尿の保存方法および採尿用キット |
| US6587829B1 (en) * | 1997-07-31 | 2003-07-01 | Schering Corporation | Method and apparatus for improving patient compliance with prescriptions |
| US6421650B1 (en) * | 1998-03-04 | 2002-07-16 | Goetech Llc | Medication monitoring system and apparatus |
| US5945123A (en) * | 1998-04-02 | 1999-08-31 | K-V Pharmaceutical Company | Maximizing effectiveness of substances used to improve health and well being |
| US20040062802A1 (en) * | 1998-04-02 | 2004-04-01 | Hermelin Victor M. | Maximizing effectiveness of substances used to improve health and well being |
| US6397190B1 (en) * | 1998-07-22 | 2002-05-28 | Gerald E. Goetz | Veterinary medication monitoring system and apparatus |
| US7069227B1 (en) | 1999-02-05 | 2006-06-27 | Zansor Systems, Llc | Healthcare information network |
| US7069226B1 (en) * | 1999-07-07 | 2006-06-27 | Synetic, Incorporated | Prescription data processing system for determining new therapy starts |
| JP4773019B2 (ja) * | 1999-11-08 | 2011-09-14 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 薬物の服薬遵守を監視するためのマーカー検出の方法および器具 |
| US20030194374A1 (en) * | 2001-01-17 | 2003-10-16 | Xanodyne Pharmacal, Inc. | Compositions including a visual marker and method of use thereof |
| US7062312B2 (en) | 2001-01-17 | 2006-06-13 | Pediamed Pharmaceuticals, Inc. | Combination and method including a visual marker for determining compliance with a medication regimen |
| US20020143579A1 (en) * | 2001-03-30 | 2002-10-03 | Docherty John P. | System and method for targeted interventions of physician prescription practices based on deviations from expert guidelines |
| US7415447B2 (en) * | 2001-04-02 | 2008-08-19 | Invivodata, Inc. | Apparatus and method for prediction and management of participant compliance in clinical research |
| US8533029B2 (en) | 2001-04-02 | 2013-09-10 | Invivodata, Inc. | Clinical monitoring device with time shifting capability |
| US8065180B2 (en) | 2001-04-02 | 2011-11-22 | invivodata®, Inc. | System for clinical trial subject compliance |
| US7873589B2 (en) * | 2001-04-02 | 2011-01-18 | Invivodata, Inc. | Operation and method for prediction and management of the validity of subject reported data |
| US20030110060A1 (en) * | 2001-12-12 | 2003-06-12 | Clementi William A. | Method of providing comprehensive drug compliance information |
| US7585680B2 (en) * | 2003-08-28 | 2009-09-08 | Marshfield Medical Research And Education Foundation | Method and device for monitoring medication usage |
| US8781857B2 (en) | 2003-09-19 | 2014-07-15 | Tag, Llc | Method for competitive prescription drug and/or bidding service provider selection |
| WO2005029276A2 (en) * | 2003-09-19 | 2005-03-31 | Tag, Llc | Method for competitive prescription drug and/or bidding service provider selection |
| US20060184473A1 (en) * | 2003-11-19 | 2006-08-17 | Eder Jeff S | Entity centric computer system |
| EP1768668A2 (de) | 2004-06-16 | 2007-04-04 | Tap Pharmaceutical Products, Inc. | Multi-ppi-dosierform |
| US8296162B1 (en) | 2005-02-01 | 2012-10-23 | Webmd Llc. | Systems, devices, and methods for providing healthcare information |
| JP2009528640A (ja) * | 2006-03-01 | 2009-08-06 | タグ,エルエルシー | 競合処方薬および/または入札サービスプロバイダ選択のための方法 |
| CA2653346A1 (en) * | 2006-06-01 | 2007-12-06 | Igeacare Systems, Inc. | Remote health care system with treatment verification |
| CA2653447A1 (en) * | 2006-06-01 | 2008-05-08 | Igeacare Systems, Inc. | Remote health care diagnostic tool |
| WO2008020325A2 (en) * | 2006-06-01 | 2008-02-21 | Rajiv Muradia | Home based healthcare system and method |
| WO2008035211A2 (en) * | 2006-06-01 | 2008-03-27 | Rajiv Muradia | Remote health care system with stethoscope |
| WO2008070618A2 (en) * | 2006-12-01 | 2008-06-12 | Ameritox, Ltd. | Method and apparatus for generating toxicology reports |
| KR100867324B1 (ko) | 2007-03-13 | 2008-11-06 | 가톨릭대학교 산학협력단 | 혈중약물농도측정 처방 자동화 방법 |
| KR20100116165A (ko) | 2007-10-12 | 2010-10-29 | 다케다 파마슈티칼스 노쓰 어메리카, 인코포레이티드 | 음식 섭취와 관계없이 위장 장애를 치료하는 방법 |
| US8380531B2 (en) | 2008-07-25 | 2013-02-19 | Invivodata, Inc. | Clinical trial endpoint development process |
| JP2012500403A (ja) * | 2008-08-18 | 2012-01-05 | ベックマン コールター, インコーポレイテッド | 正規化された10進相当システムおよび方法 |
| AU2011215707A1 (en) * | 2010-02-11 | 2012-09-20 | Ameritox Limited Partnership | Methods of normalizing measured drug concentrations and testing for non-compliance with a drug treatment regimen |
| WO2011099984A1 (en) * | 2010-02-11 | 2011-08-18 | Harry Leider | Methods of normalizing measured drug concentrations and testing for non-compliance with a drug treatment regimen |
| EP2542276A1 (de) * | 2010-03-05 | 2013-01-09 | B. Braun Melsungen AG | System und verfahren zur verabreichung von medikamenten für einen patienten |
| US10276054B2 (en) | 2011-11-29 | 2019-04-30 | Eresearchtechnology, Inc. | Methods and systems for data analysis |
| CA2936746C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| US9858063B2 (en) | 2016-02-10 | 2018-01-02 | Vignet Incorporated | Publishing customized application modules |
| US12217036B2 (en) | 2016-02-10 | 2025-02-04 | Vignet Incorporated | Automating interactions for health data collection and patient engagement |
| US9928230B1 (en) | 2016-09-29 | 2018-03-27 | Vignet Incorporated | Variable and dynamic adjustments to electronic forms |
| EP3713477B1 (de) | 2017-11-21 | 2022-07-06 | MX3 Diagnostics, Inc. | Speicheltestsystem und verfahren |
| US10775974B2 (en) | 2018-08-10 | 2020-09-15 | Vignet Incorporated | User responsive dynamic architecture |
| JP2022508683A (ja) | 2018-10-11 | 2022-01-19 | エムエックススリー・ダイアグノスティクス・インコーポレイテッド | イオン選択センサ |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| US11701036B2 (en) | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
| WO2021146407A1 (en) | 2020-01-15 | 2021-07-22 | MX3 Diagnostics, Inc. | Assessment of biomarker concentration in a fluid |
| US11703436B2 (en) | 2020-01-30 | 2023-07-18 | MX3 Diagnostics, Inc. | Biological fluid sample assessment |
| US11328796B1 (en) | 2020-02-25 | 2022-05-10 | Vignet Incorporated | Techniques for selecting cohorts for decentralized clinical trials for pharmaceutical research |
| US11605038B1 (en) | 2020-05-18 | 2023-03-14 | Vignet Incorporated | Selecting digital health technology to achieve data collection compliance in clinical trials |
| US11461216B1 (en) | 2020-05-18 | 2022-10-04 | Vignet Incorporated | Monitoring and improving data collection using digital health technology |
| US12230406B2 (en) | 2020-07-13 | 2025-02-18 | Vignet Incorporated | Increasing diversity and engagement in clinical trails through digital tools for health data collection |
| US11763919B1 (en) | 2020-10-13 | 2023-09-19 | Vignet Incorporated | Platform to increase patient engagement in clinical trials through surveys presented on mobile devices |
| US11417418B1 (en) | 2021-01-11 | 2022-08-16 | Vignet Incorporated | Recruiting for clinical trial cohorts to achieve high participant compliance and retention |
| US11240329B1 (en) | 2021-01-29 | 2022-02-01 | Vignet Incorporated | Personalizing selection of digital programs for patients in decentralized clinical trials and other health research |
| US11789837B1 (en) | 2021-02-03 | 2023-10-17 | Vignet Incorporated | Adaptive data collection in clinical trials to increase the likelihood of on-time completion of a trial |
| US11196656B1 (en) | 2021-02-03 | 2021-12-07 | Vignet Incorporated | Improving diversity in cohorts for health research |
| US11586524B1 (en) | 2021-04-16 | 2023-02-21 | Vignet Incorporated | Assisting researchers to identify opportunities for new sub-studies in digital health research and decentralized clinical trials |
| US11361846B1 (en) | 2021-02-03 | 2022-06-14 | Vignet Incorporated | Systems and methods for customizing monitoring programs involving remote devices |
| US12211594B1 (en) | 2021-02-25 | 2025-01-28 | Vignet Incorporated | Machine learning to predict patient engagement and retention in clinical trials and increase compliance with study aims |
| US11281553B1 (en) | 2021-04-16 | 2022-03-22 | Vignet Incorporated | Digital systems for enrolling participants in health research and decentralized clinical trials |
| US11316941B1 (en) | 2021-02-03 | 2022-04-26 | Vignet Incorporated | Remotely managing and adapting monitoring programs using machine learning predictions |
| US11521714B1 (en) | 2021-02-03 | 2022-12-06 | Vignet Incorporated | Increasing diversity of participants in health research using adaptive methods |
| US11296971B1 (en) | 2021-02-03 | 2022-04-05 | Vignet Incorporated | Managing and adapting monitoring programs |
| US12248383B1 (en) | 2021-02-25 | 2025-03-11 | Vignet Incorporated | Digital systems for managing health data collection in decentralized clinical trials |
| US12248384B1 (en) | 2021-02-25 | 2025-03-11 | Vignet Incorporated | Accelerated clinical trials using patient-centered, adaptive digital health tools |
| US11636500B1 (en) | 2021-04-07 | 2023-04-25 | Vignet Incorporated | Adaptive server architecture for controlling allocation of programs among networked devices |
| US11901083B1 (en) | 2021-11-30 | 2024-02-13 | Vignet Incorporated | Using genetic and phenotypic data sets for drug discovery clinical trials |
| US11705230B1 (en) | 2021-11-30 | 2023-07-18 | Vignet Incorporated | Assessing health risks using genetic, epigenetic, and phenotypic data sources |
| CN114371238A (zh) * | 2022-01-11 | 2022-04-19 | 中国水产科学研究院长江水产研究所 | 一种生产状态下水产动物休药期的测定方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2564247A (en) * | 1947-08-18 | 1951-08-14 | Richard M Carson | Method of testing urine to determine pregnancy |
| US3856469A (en) * | 1973-01-02 | 1974-12-24 | Syva Corp | Interferant removal from amphetamine immunoassay |
| US3901655A (en) * | 1973-12-26 | 1975-08-26 | American Cyanamid Co | Urine toxicology control |
| US4104367A (en) * | 1976-10-13 | 1978-08-01 | Hoffmann-La Roche Inc. | Radioimmunoassay for methadone |
| US4196185A (en) * | 1978-06-05 | 1980-04-01 | Hoffmann-La Roche Inc. | Immunoassay for phencyclidine |
| JPH0698032B2 (ja) * | 1987-01-23 | 1994-12-07 | 財団法人野田産業科学研究所 | クレアチンもしくはクレアチニンの測定法及びこれらの測定用試薬 |
| US5137692A (en) * | 1990-12-11 | 1992-08-11 | Robert Fritz | Nitrogen test kit for physical training |
| US5179027A (en) * | 1991-01-10 | 1993-01-12 | Fisher Murray M | Method employing chemical markers and kit for verifying the source and completeness of urine samples for testing for the presence of drugs of abuse |
| US5547878A (en) * | 1993-11-02 | 1996-08-20 | Kell; Michael | Method of monitoring patient compliance with medications prescriptions |
-
1994
- 1994-10-19 AU AU80873/94A patent/AU698403B2/en not_active Ceased
- 1994-10-19 DE DE69432976T patent/DE69432976D1/de not_active Expired - Lifetime
- 1994-10-19 JP JP51325495A patent/JP4389005B2/ja not_active Expired - Fee Related
- 1994-10-19 CA CA002175584A patent/CA2175584C/en not_active Expired - Lifetime
- 1994-10-19 AT AT94931983T patent/ATE245814T1/de not_active IP Right Cessation
- 1994-10-19 EP EP94931983A patent/EP0748444B1/de not_active Expired - Lifetime
- 1994-10-19 WO PCT/US1994/012119 patent/WO1995012812A1/en not_active Ceased
-
1996
- 1996-07-05 US US08/675,863 patent/US5652146A/en not_active Expired - Lifetime
- 1996-08-19 US US08/697,063 patent/US5908788A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2175584C (en) | 2005-07-12 |
| EP0748444A1 (de) | 1996-12-18 |
| US5652146A (en) | 1997-07-29 |
| DE69432976D1 (de) | 2003-08-28 |
| JPH09508967A (ja) | 1997-09-09 |
| AU698403B2 (en) | 1998-10-29 |
| WO1995012812A1 (en) | 1995-05-11 |
| AU8087394A (en) | 1995-05-23 |
| EP0748444A4 (de) | 1997-08-27 |
| EP0748444B1 (de) | 2003-07-23 |
| JP4389005B2 (ja) | 2009-12-24 |
| US5908788A (en) | 1999-06-01 |
| CA2175584A1 (en) | 1995-05-11 |
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