ATE243712T1 - Vekürztes insulinähnlichen wachstumsfaktor- bindendes protein mit mitogener aktivität - Google Patents

Vekürztes insulinähnlichen wachstumsfaktor- bindendes protein mit mitogener aktivität

Info

Publication number
ATE243712T1
ATE243712T1 AT94902200T AT94902200T ATE243712T1 AT E243712 T1 ATE243712 T1 AT E243712T1 AT 94902200 T AT94902200 T AT 94902200T AT 94902200 T AT94902200 T AT 94902200T AT E243712 T1 ATE243712 T1 AT E243712T1
Authority
AT
Austria
Prior art keywords
insulin
growth factor
binding protein
shortened
mitogenic activity
Prior art date
Application number
AT94902200T
Other languages
English (en)
Inventor
Dennis L Andress
Michael C Kiefer
Original Assignee
Chiron Corp
Dennis L Andress
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp, Dennis L Andress filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE243712T1 publication Critical patent/ATE243712T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT94902200T 1992-11-04 1993-10-29 Vekürztes insulinähnlichen wachstumsfaktor- bindendes protein mit mitogener aktivität ATE243712T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97214292A 1992-11-04 1992-11-04
PCT/US1993/010462 WO1994010207A2 (en) 1992-11-04 1993-10-29 Truncated insulin-like growth factor binding proteins having mitogenic activity

Publications (1)

Publication Number Publication Date
ATE243712T1 true ATE243712T1 (de) 2003-07-15

Family

ID=25519236

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94902200T ATE243712T1 (de) 1992-11-04 1993-10-29 Vekürztes insulinähnlichen wachstumsfaktor- bindendes protein mit mitogener aktivität

Country Status (8)

Country Link
US (3) US6369029B1 (de)
EP (1) EP0668879B1 (de)
JP (4) JPH08509595A (de)
AT (1) ATE243712T1 (de)
AU (1) AU686585B2 (de)
CA (1) CA2148685A1 (de)
DE (1) DE69333063T2 (de)
WO (1) WO1994010207A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5847099A (en) * 1994-10-19 1998-12-08 Genetics Institute, Inc. TNF receptor death domain ligand proteins
US5712381A (en) 1994-10-19 1998-01-27 Genetics Institute, Inc. MADD, a TNF receptor death domain ligand protein
US5849501A (en) * 1994-10-19 1998-12-15 Genetics Institute, Inc. TNF receptor death domain ligand proteins and method to identify inhibitors of ligand binding
US5852173A (en) * 1994-10-19 1998-12-22 Genetics Institute, Inc. TNF receptor death ligand proteins and inhibitors of ligand binding
DE19757250A1 (de) * 1997-12-22 1999-07-01 Forssmann Wolf Georg Prof Dr Insulin-like growth factor binding protein und seine Verwendung
US7109030B2 (en) * 2000-03-31 2006-09-19 Nuvelo, Inc. Methods of therapy and diagnosis using insulin-like growth factor binding protein-like polypeptides and polynucleotides
US7071160B2 (en) * 2000-06-15 2006-07-04 Kyowa Hakko Kogyo Co., Ltd. Insulin-like growth factor-binding protein
AU2002246554A1 (en) * 2000-10-24 2002-08-06 Dennis L. Andress Methods for increasing bone formation and enhancing bone accretion
WO2004035132A2 (en) * 2002-10-15 2004-04-29 Irm Llc Compositions and methods for inducing osteogenesis
CA2541015A1 (en) * 2003-10-03 2005-04-14 Genentech, Inc. Igf binding proteins
JP4976852B2 (ja) * 2003-11-10 2012-07-18 ザ スクリプス リサーチ インスティチュート 細胞脱分化を誘導するための組成物および方法
RU2487735C1 (ru) * 2012-04-02 2013-07-20 Федеральное государственное бюджетное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А. Илизарова" Министерства здравоохранения и социального развития Российской Федерации Способ дифференцированной стимуляции репаративной регенерации тканей при моделировании внутрисуставных переломов вертлужной впадины

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
WO1989009792A1 (en) 1988-04-12 1989-10-19 Synergen, Inc. Method for potentiating and inhibiting insulin-like growth factor activity
EP0424416B1 (de) 1988-07-15 1995-07-19 Central Sydney Area Health Service Säureempfindliche subeinheit eines insulinähnlichen wachstumfaktors-bindeprotein-komplexes
PT98803B (pt) 1990-08-28 1999-01-29 Chiron Corp Processo de preparacao de uma proteina de ligacao purificada
JPH06503949A (ja) 1990-08-28 1994-05-12 カイロン　コーポレイション 新規インシュリン様成長因子結合タンパク質ｉｇｆｂｐ―５
US5212074A (en) 1990-08-28 1993-05-18 Chiron Corporation Genetic material encoding new insulin-like growth factor binding protein igfbp-6
CA2090705A1 (en) 1990-08-28 1992-03-01 Michael C. Kiefer Genetic material encoding igfbp-5
EP0556344B1 (de) 1991-01-08 2003-08-13 Chiron Corporation Insulinartigen wachstumsfaktor bindendes protein
WO1992014834A1 (en) * 1991-02-14 1992-09-03 The Whittier Institute For Diabetes And Endocrinology Insulin-like growth factor binding protein
US5118667A (en) * 1991-05-03 1992-06-02 Celtrix Pharmaceuticals, Inc. Bone growth factors and inhibitors of bone resorption for promoting bone formation

Also Published As

Publication number Publication date
JP2004307510A (ja) 2004-11-04
EP0668879B1 (de) 2003-06-25
AU686585B2 (en) 1998-02-12
CA2148685A1 (en) 1994-05-11
JP2008148711A (ja) 2008-07-03
JP2006016405A (ja) 2006-01-19
DE69333063T2 (de) 2004-05-13
WO1994010207A3 (en) 1994-07-07
US6391588B1 (en) 2002-05-21
DE69333063D1 (de) 2003-08-07
US6369029B1 (en) 2002-04-09
AU5665294A (en) 1994-05-24
JPH08509595A (ja) 1996-10-15
US6489294B1 (en) 2002-12-03
EP0668879A1 (de) 1995-08-30
WO1994010207A2 (en) 1994-05-11

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