ATE241807T1 - Immunoassay zum nachweis des mutanten p53 polypeptids in biologischen flüssigkeiten - Google Patents
Immunoassay zum nachweis des mutanten p53 polypeptids in biologischen flüssigkeitenInfo
- Publication number
- ATE241807T1 ATE241807T1 AT92906415T AT92906415T ATE241807T1 AT E241807 T1 ATE241807 T1 AT E241807T1 AT 92906415 T AT92906415 T AT 92906415T AT 92906415 T AT92906415 T AT 92906415T AT E241807 T1 ATE241807 T1 AT E241807T1
- Authority
- AT
- Austria
- Prior art keywords
- mutant
- polypeptide
- immunoassay
- detection
- biological liquids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64956691A | 1991-02-01 | 1991-02-01 | |
US71917291A | 1991-06-21 | 1991-06-21 | |
PCT/US1992/000878 WO1992013970A1 (en) | 1991-02-01 | 1992-01-31 | Immunoassay for detection of mutant p53 polypeptide in biological fluids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE241807T1 true ATE241807T1 (de) | 2003-06-15 |
Family
ID=27095640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92906415T ATE241807T1 (de) | 1991-02-01 | 1992-01-31 | Immunoassay zum nachweis des mutanten p53 polypeptids in biologischen flüssigkeiten |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP1006364A1 (de) |
AT (1) | ATE241807T1 (de) |
AU (1) | AU1370592A (de) |
DE (1) | DE69233079T2 (de) |
WO (1) | WO1992013970A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07505719A (ja) * | 1992-04-14 | 1995-06-22 | デューク・ユニバーシティー | p53及びHSP70のコンプレックスを含む腫瘍の検出方法 |
JPH07501711A (ja) * | 1992-09-30 | 1995-02-23 | ドイチェス クレブスフォーシュングスツェントラム スチフトゥング デス エフェントリヒェン レヒツ | p53特異的抗体の検出法 |
CA2128833C (en) * | 1993-08-02 | 2004-10-05 | Molly F. Kulesz-Martin | P53as protein and antibody therefor |
US5726024A (en) * | 1993-08-02 | 1998-03-10 | Health Research, Inc. | p53as protein and antibody therefor |
US7238523B1 (en) | 1993-08-02 | 2007-07-03 | Health Research, Inc. | p53as protein and antibody therefor |
US6965009B1 (en) | 1993-08-02 | 2005-11-15 | Health Research, Inc. | p53 as protein and antibody therefor |
US5747650A (en) * | 1993-08-02 | 1998-05-05 | Health Research, Inc. | P53AS protein and antibody therefor |
US5688918A (en) * | 1993-08-02 | 1997-11-18 | Health Research, Inc. | p53as protein and antibody therefor |
SE9403953D0 (sv) * | 1994-07-15 | 1994-11-16 | Pharmacia Biotech Ab | Sequence-based diagnosis |
US6072034A (en) * | 1997-11-22 | 2000-06-06 | Duke University | Gene product over expressed in cancer cells |
US5912142A (en) * | 1996-11-22 | 1999-06-15 | Duke University | Gene product over expressed in cancer cells |
US6350615B1 (en) | 1996-11-22 | 2002-02-26 | Duke University | Gene product over expressed in cancer cells |
IL121041A0 (en) | 1997-06-09 | 1997-11-20 | Yeda Res & Dev | Immunogenic compositions for induction of anti-tumor immunity |
WO1999002682A1 (en) * | 1997-07-09 | 1999-01-21 | Affymetrix, Inc. | p53 MUTANTS FOUND IN TUMORS |
CA2214461A1 (en) | 1997-09-02 | 1999-03-02 | Mcgill University | Screening method for determining individuals at risk of developing diseases associated with different polymorphic forms of wildtype p53 |
CN101080638A (zh) | 2004-10-14 | 2007-11-28 | 健泰科生物技术公司 | Cop1分子及其用途 |
GB201617564D0 (en) | 2016-10-17 | 2016-11-30 | Agency For Science Technology And Research And National University Of Singapore And Singapore Health | Anti-p53 antibodies |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
US4798787A (en) * | 1984-09-19 | 1989-01-17 | Cetus Corporation | Peptide antibodies and their use in detecting oncogene products |
DE4444969C1 (de) * | 1994-12-16 | 1996-10-24 | Orga Med Dr Med Erwin Klopfer | Nachweis von Antikörpern gegen p53 in Körperflüssigkeiten |
-
1992
- 1992-01-31 AU AU13705/92A patent/AU1370592A/en not_active Abandoned
- 1992-01-31 EP EP99126040A patent/EP1006364A1/de not_active Withdrawn
- 1992-01-31 DE DE69233079T patent/DE69233079T2/de not_active Expired - Lifetime
- 1992-01-31 EP EP92906415A patent/EP0576476B1/de not_active Expired - Lifetime
- 1992-01-31 WO PCT/US1992/000878 patent/WO1992013970A1/en active IP Right Grant
- 1992-01-31 AT AT92906415T patent/ATE241807T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69233079T2 (de) | 2004-04-01 |
EP0576476B1 (de) | 2003-05-28 |
EP0576476A4 (en) | 1994-06-29 |
EP1006364A1 (de) | 2000-06-07 |
AU1370592A (en) | 1992-09-07 |
WO1992013970A1 (en) | 1992-08-20 |
EP0576476A1 (de) | 1994-01-05 |
DE69233079D1 (de) | 2003-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |