ATE240769T1 - Fermentationsprozess mittels zentrifugation - Google Patents

Fermentationsprozess mittels zentrifugation

Info

Publication number
ATE240769T1
ATE240769T1 AT96911456T AT96911456T ATE240769T1 AT E240769 T1 ATE240769 T1 AT E240769T1 AT 96911456 T AT96911456 T AT 96911456T AT 96911456 T AT96911456 T AT 96911456T AT E240769 T1 ATE240769 T1 AT E240769T1
Authority
AT
Austria
Prior art keywords
liquid flow
biocatalysts
immobilized
centrifugation
density
Prior art date
Application number
AT96911456T
Other languages
English (en)
Inventor
Heath H Herman
Original Assignee
Kinetic Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinetic Biosystems Inc filed Critical Kinetic Biosystems Inc
Application granted granted Critical
Publication of ATE240769T1 publication Critical patent/ATE240769T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/12—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96911456T 1995-03-28 1996-03-27 Fermentationsprozess mittels zentrifugation ATE240769T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/412,289 US5622819A (en) 1995-03-28 1995-03-28 Centrifugal fermentation process
PCT/US1996/004243 WO1996030101A1 (en) 1995-03-28 1996-03-27 Centrifugal fermentation process

Publications (1)

Publication Number Publication Date
ATE240769T1 true ATE240769T1 (de) 2003-06-15

Family

ID=23632408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96911456T ATE240769T1 (de) 1995-03-28 1996-03-27 Fermentationsprozess mittels zentrifugation

Country Status (7)

Country Link
US (2) US5622819A (de)
EP (1) EP0820337B1 (de)
JP (2) JPH11502715A (de)
AT (1) ATE240769T1 (de)
CA (1) CA2216467A1 (de)
DE (1) DE69628291T2 (de)
WO (1) WO1996030101A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5960344A (en) * 1993-12-20 1999-09-28 Norand Corporation Local area network having multiple channel wireless access
US6916652B2 (en) * 1995-03-28 2005-07-12 Kinetic Biosystems, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation
US6214617B1 (en) * 1995-03-28 2001-04-10 Kinetic Biosystems, Inc. Centrifugal fermentation process
US20050266548A1 (en) * 1995-03-28 2005-12-01 Kbi Biopharma, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor
US20030064428A1 (en) * 1998-12-31 2003-04-03 Herman Heath H. Methods and devices for remediation and fermentation
US6660509B1 (en) 1995-03-28 2003-12-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
EP1555069B1 (de) * 1995-04-18 2007-10-31 Gambro BCT, Inc. Vorrichtung und Verfahren zur Teilchentrennung
US5951877A (en) * 1995-04-18 1999-09-14 Cobe Laboratories, Inc. Particle filter method
US5945002A (en) * 1995-09-01 1999-08-31 Water Research Committe Method of producing secondary metabolites
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
AU5895898A (en) * 1996-12-20 1998-07-17 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
US6083293A (en) * 1997-02-24 2000-07-04 Bath; Virginia L. Method for enhanced plant protein production and composition for use in the same
US6632399B1 (en) * 1998-05-22 2003-10-14 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays
WO1998053311A2 (en) * 1997-05-23 1998-11-26 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
WO1999033950A2 (en) * 1997-12-31 1999-07-08 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6051146A (en) * 1998-01-20 2000-04-18 Cobe Laboratories, Inc. Methods for separation of particles
JP2002515239A (ja) * 1998-05-21 2002-05-28 キネティック バイオシステムズ，インコーポレイテッド 改善および発酵のための方法および装置
US6153113A (en) * 1999-02-22 2000-11-28 Cobe Laboratories, Inc. Method for using ligands in particle separation
US6582662B1 (en) * 1999-06-18 2003-06-24 Tecan Trading Ag Devices and methods for the performance of miniaturized homogeneous assays
DE19953424B4 (de) * 1999-11-06 2006-04-13 Universität Leipzig Verfahren und Anordnung zur Charakterisierung und Vereinzelung von multizellulären Sphäroiden
US6703217B2 (en) 2000-01-31 2004-03-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US6354986B1 (en) 2000-02-16 2002-03-12 Gambro, Inc. Reverse-flow chamber purging during centrifugal separation
US6635441B2 (en) 2001-02-08 2003-10-21 Irm, Llc Multi-sample fermentor and method of using same
US7326564B2 (en) 2001-02-20 2008-02-05 St. Jude Medical, Inc. Flow system for medical device evaluation and production
US6869792B2 (en) 2001-03-16 2005-03-22 Irm, Llc Method and apparatus for performing multiple processing steps on a sample in a single vessel
EP1451357A4 (de) * 2001-11-01 2005-10-26 Univ California Biokatalytische sol-gel-mikroarrays
JP4139333B2 (ja) * 2001-11-09 2008-08-27 キネティック バイオシステムズ インコーポレイテッド クロマトグラフィー用の方法及び組成物
DE10209609A1 (de) * 2002-03-05 2003-10-02 Europ Lab Molekularbiolog Verfahren und Vorrichtung zur Parallelanalyse von Bio-Molekülen
JP2004081090A (ja) * 2002-08-26 2004-03-18 National Institute For Materials Science 細胞培養方法とその装置
JP4666335B2 (ja) * 2002-09-04 2011-04-06 晶夫 岸田 機械的振動による生物機能の制御方法とその装置
US7968335B2 (en) * 2004-06-17 2011-06-28 Ken Nakata Cell culturing method using biomechanical stimulation loading and system therefor
US20060147895A1 (en) * 2004-10-22 2006-07-06 Cryofacets, Inc. System, chamber, and method for fractionation, elutriation, and decontamination of fluids containing cellular components
WO2006047296A1 (en) * 2004-10-22 2006-05-04 Cryofacets, Inc. System, chamber, and method for fractionation and elutriation of fluids containing particulate components
US9057044B2 (en) 2006-08-30 2015-06-16 Meir Israelowitz Laminar flow reactor
DE102007020671A1 (de) * 2007-05-01 2008-11-06 Justus-Liebig-Universität Giessen Verfahren und Vorrichtung zum kontaktfreien Materialwachstum in einer strömenden Lösung (FLow suspended solution growth (FSSG))
PT2271200E (pt) 2008-04-10 2014-09-30 Georgia Tech Res Inst Métodos para dispersar embriões de plantas somáticos
US9631174B2 (en) 2008-04-10 2017-04-25 Georgia Tech Research Corporation Methods and devices for dispersing somatic plant embryos
SG192529A1 (en) * 2008-07-16 2013-08-30 Kbi Biopharma Inc Methods and systems for manipulating particles using a fluidized bed
CA2763928A1 (en) * 2009-06-03 2010-12-09 Aarhus Universitet Submerged perfusion bioreactor
EP2309266A1 (de) * 2009-09-21 2011-04-13 F. Hoffmann-La Roche AG Verfahren zur Durchführung von Reaktionen in einer Analysevorrichtung
US9839920B2 (en) 2009-10-06 2017-12-12 Satorius Stedim North America Inc. Apparatus for manipulating particles using at least one chamber having an inlet and an opposed outlet
BR112012007787A2 (pt) * 2009-10-09 2017-05-09 Georgia Tech Res Inst dispositivo separador, dispositivo de deposição e sistema para a manipulação de embriões vegetais somáticos
WO2011043731A1 (en) 2009-10-09 2011-04-14 Georgia Tech Research Corporation Method and device for dispersion of assemblies of biological material
US10004189B2 (en) 2009-10-09 2018-06-26 Georgia Tech Research Corporation Separator device, deposition device and system for handling of somatic plant embryos
DE102010005415B4 (de) 2010-01-22 2015-07-16 Zellwerk Gmbh Verfahren und Vorrichtung zur dynamischen Expansion und/oder Differenzierung von suspendierten primären Zellen oder Stammzellen humanen und tierischen Ursprungs
US10260036B2 (en) 2014-10-17 2019-04-16 Sani-Tech West, Inc. Mixing and filtering system and method
EP3797149A1 (de) 2018-05-22 2021-03-31 Nantkwest, Inc. Verfahren und systeme zur zellbettbildung während der bioverarbeitung

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2616619A (en) * 1948-08-30 1952-11-04 Norman A Macleod Method and apparatus for centrifugal elutriation
US3450598A (en) * 1965-08-24 1969-06-17 Flow Lab Method for cell propagation
US3580840A (en) * 1969-03-18 1971-05-25 Litton Systems Inc Process for treating sewage and other contaminated waters
FR2053565A5 (de) * 1969-07-09 1971-04-16 Pasteur Institut
US3753731A (en) * 1971-03-16 1973-08-21 C Christ Process and apparatus for fermentation
US3941662A (en) * 1971-06-09 1976-03-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Apparatus for culturing cells
US3865695A (en) * 1971-06-25 1975-02-11 Agricole De Mycelium Du Centre Culture of mycelium
US4203801A (en) * 1972-04-26 1980-05-20 Burroughs Wellcome Co. Cell and virus culture systems
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes
US3883393A (en) * 1972-05-18 1975-05-13 Us Health Education & Welfare Cell culture on semi-permeable tubular membranes
US3843454A (en) * 1972-07-31 1974-10-22 Abbott Lab Flow through tissue culture propagator
US3871961A (en) * 1973-03-15 1975-03-18 Matilde Gianessi Method for accelerating the growth and increasing the yield of microorganisms
US3968035A (en) * 1973-04-05 1976-07-06 Eli Lilly And Company Super-oxygenation method
US3948732A (en) * 1973-05-31 1976-04-06 Instrumentation Laboratory, Inc. Cell culture assembly
CH593339A5 (de) * 1973-07-02 1977-11-30 Monsanto Co
US3928142A (en) * 1973-07-24 1975-12-23 Dennis B Smith Culture chamber for the study of biological systems and method of fabrication thereof
CH587915A5 (de) * 1974-05-28 1977-05-13 Nestle Societe D Assistance Te
US4113173A (en) * 1975-03-27 1978-09-12 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing apparatus
US4036693A (en) * 1976-02-02 1977-07-19 Massachusetts Institute Of Technology Treatment of cell culture microcarries
US4425112A (en) * 1976-02-25 1984-01-10 The United States Of America As Represented By The Department Of Health And Human Services Flow-through centrifuge
US4201845A (en) * 1976-04-12 1980-05-06 Monsanto Company Cell culture reactor
US4087327A (en) * 1976-04-12 1978-05-02 Monsanto Company Mammalion cell culture process
US4148689A (en) * 1976-05-14 1979-04-10 Sanraku-Ocean Co., Ltd. Immobilization of microorganisms in a hydrophilic complex gel
US4059485A (en) * 1976-11-03 1977-11-22 Monsanto Company Adaptation of cell lines to suspension culture
US4189534A (en) * 1976-11-11 1980-02-19 Massachusetts Institute Of Technology Cell culture microcarriers
US4169010A (en) * 1976-11-18 1979-09-25 Phillips Petroleum Company Fermentation process for improved oxygen utilization
US4195131A (en) * 1977-03-09 1980-03-25 Papas Gary R Environmentally controlled unit
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
US4114802A (en) * 1977-08-29 1978-09-19 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with biaxial connector
US4293654A (en) * 1977-10-17 1981-10-06 Massachusetts Institute Of Technology Cell culture microcarriers
US4184922A (en) * 1977-11-11 1980-01-22 The Government Of The United States Dual circuit, woven artificial capillary bundle for cell culture
US4178209A (en) * 1977-11-14 1979-12-11 Monsanto Company Continuous cell culture method and apparatus
US4184916A (en) * 1977-11-14 1980-01-22 Monsanto Company Continuous cell culture system
US4166768A (en) * 1977-11-14 1979-09-04 Monsanto Company Continuous cell culture system
JPS54114474A (en) * 1978-02-28 1979-09-06 Ebara Corp Method and apparatus for centrifugal fluidization
US4220725A (en) * 1978-04-03 1980-09-02 United States Of America Capillary cell culture device
US4237218A (en) * 1979-02-09 1980-12-02 Bio-Rad Laboratories, Inc. Micro-carrier cell culture
JPS5819344B2 (ja) * 1979-02-26 1983-04-18 テルモ株式会社 流体の遠心分離装置
US4279753A (en) * 1979-03-19 1981-07-21 Arco Environmental Company Wastewater treatment system including multiple stages of alternate aerobic-anerobic bioreactors in series
US4237033A (en) * 1979-04-23 1980-12-02 Merck & Co., Inc. Pretreatment of microcarriers for cell culture
US4266032A (en) * 1979-08-10 1981-05-05 Monsanto Company Method of culturing microcarrier supported cells
JPS5642584A (en) * 1979-09-18 1981-04-20 Asahi Chem Ind Co Ltd Cell cultivation method
US4308351A (en) * 1980-04-18 1981-12-29 Joseph Leighton System for growing tissue cultures
JPS575684A (en) * 1980-06-11 1982-01-12 Kikkoman Corp Preparation of vinegar and its apparatus
US4289854A (en) * 1980-06-20 1981-09-15 Monsanto Company Cell culture method and apparatus
US4442206A (en) * 1980-08-21 1984-04-10 Stanford University Method of using isotropic, porous-wall polymeric membrane, hollow-fibers for culture of microbes
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
US4372484A (en) * 1981-02-04 1983-02-08 Gambro Ab Device for the separation of a liquid, especially whole blood
DK147077C (da) * 1981-11-16 1984-09-10 Nunc As Celledyrkningsbeholder
US4413058A (en) * 1982-01-28 1983-11-01 Arcuri Edward J Continuous production of ethanol by use of flocculent zymomonas mobilis
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
US4557504A (en) * 1983-01-17 1985-12-10 Kuhns Roger J Method for thwarting forgery of fingerprint-bearing identification media
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4837390A (en) * 1983-05-11 1989-06-06 Keyes Offshore, Inc. Hyperbaric organ preservation apparatus and method for preserving living organs
US4764471A (en) * 1984-01-04 1988-08-16 Nabisco Brands, Inc. Continuous bioreactor and process
US4603109A (en) * 1984-06-01 1986-07-29 Norton Company Method and apparatus for contacting reactants in chemical and biological reactions
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
US4748124A (en) * 1984-10-30 1988-05-31 E. I. Du Pont De Nemours And Company Compartmentalized cell-culture device and method
GB2168904B (en) * 1984-11-30 1988-01-27 Ceskoslovenska Akademie Ved Method of circulation of liquid phase through a solid phase particularly for biocatalytical reactions and a device for realization thereof
GB8508976D0 (en) * 1985-04-04 1985-05-09 Davies G A Reactor unit
JPS62100279A (ja) * 1985-10-25 1987-05-09 Sanki Eng Kk 固定化生体触媒反応器
US4722902A (en) * 1985-11-04 1988-02-02 Endotronics, Inc. Apparatus and method for culturing cells, removing waste and concentrating product
US4661455A (en) * 1986-01-16 1987-04-28 Dorr-Oliver Incorporated Membrane cell culturing device
PT82225B (pt) * 1986-03-19 1989-06-30 Cipan Comp Ind Produtora De An Reactores biocataliticos para biocatalizadores imobilizados do tipo gel e outros
DE3612453A1 (de) * 1986-04-14 1987-10-15 Diessel Gmbh & Co Vorrichtung zur kultivierung von zellkulturen
US4894342A (en) * 1986-05-12 1990-01-16 C. D. Medical, Inc. Bioreactor system
EP0260627B1 (de) * 1986-09-19 1993-06-16 Shimadzu Corporation Druckbrutschrank
GB2201904B (en) * 1987-02-14 1990-12-19 Domnick Hunter Filters Ltd Device for liquid chromatography or immobilised enzyme reaction
US4939087A (en) * 1987-05-12 1990-07-03 Washington State University Research Foundation, Inc. Method for continuous centrifugal bioprocessing
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
US4839292B1 (en) * 1987-09-11 1994-09-13 Joseph G Cremonese Cell culture flask utilizing membrane barrier
US4851354A (en) * 1987-12-07 1989-07-25 Trustees Of The University Of Pennsylvania Apparatus for mechanically stimulating cells
US4908319A (en) * 1988-03-16 1990-03-13 Smyczek Peter J Laboratory apparatus
US4931401A (en) * 1988-09-01 1990-06-05 La Societe De Recherche Snc Inc. Bioreactor
US4874358A (en) * 1989-02-01 1989-10-17 Utah Bioreseach, Inc. Dual axis continuous flow centrifugation apparatus and method
US4897359A (en) * 1989-03-27 1990-01-30 Bio-Response, Inc. Apparatus for oxygenating culture medium
US4937196A (en) * 1989-08-18 1990-06-26 Brunswick Corporation Membrane bioreactor system
US5247613A (en) * 1990-05-08 1993-09-21 Thinking Machines Corporation Massively parallel processor including transpose arrangement for serially transmitting bits of data words stored in parallel
US5151368A (en) * 1991-01-11 1992-09-29 Technical Research Associates, Inc. Dual axis, continuous flow bioreactor apparatus
US5248613A (en) * 1991-07-08 1993-09-28 Roubicek Rudolf V Nonhomogeneous centrifugal film bioreactor

Also Published As

Publication number Publication date
EP0820337B1 (de) 2003-05-21
JP2005124590A (ja) 2005-05-19
CA2216467A1 (en) 1996-10-03
US5622819A (en) 1997-04-22
JPH11502715A (ja) 1999-03-09
EP0820337A4 (de) 1998-10-07
EP0820337A1 (de) 1998-01-28
DE69628291T2 (de) 2004-03-18
US5821116A (en) 1998-10-13
JP4091052B2 (ja) 2008-05-28
DE69628291D1 (de) 2003-06-26
WO1996030101A1 (en) 1996-10-03

Similar Documents

Publication Publication Date Title
ATE240769T1 (de) Fermentationsprozess mittels zentrifugation
Sorensen Somatic polymorphism and seed dispersal
CA2083816A1 (en) Method and apparatus for introducing biological substances into living cells
Yang et al. 3D acoustic manipulation of living cells and organisms based on 2D array
DE50011820D1 (de) Verfahren zur kultivierung von krebszellen aus humangewebe und vorrichtung zur aufbereitung von gewebeproben
CA2254536A1 (en) Apparatus and process for encapsulating microbial, vegetable and animal cells or biological and chemical substances
Bekers et al. Levan-ethanol biosynthesis using Zymomonas mobilis cells immobilized by attachment and entrapment
Weiss An electron microscope and biochemical study of Neurospora crassa during development
L'. Kurillova, P. Gemeiner, A. Vikartovska, H. Mikova, M. Rosenberg, M. Ilavsky Calcium pectate gel beads for cell entrapment. 6. Morphology of stabilized and hardened calcium pectate gel beads with cells for immobilized biotechnology
Solheim et al. Characterization of the substances causing deformation of root hairs of Trifolium repens when inoculated with Rhizobium trifolii
Smulson Subribosomal particles of HeLa cells
Arnold et al. Acid phosphatases of Sporothrix schenckii
EP0112154A3 (de) Verfahren zur Züchtung von lebenden Zellen
JP2002515239A5 (de)
Chandler et al. The preparation of immunogenic cell walls from a highly protective strain of Clostridium chauvoei
Kurzătkowski et al. Localization of isopenicillin N synthase in Penicillium chrysogenum PQ-96
Bayer et al. Tubular spinae are long-distance connectors between bacteria
AU6659390A (en) Methods for utilizing cell lines which lack human class ii histocompatibility antigens
CN105154480A (zh) 一种维生素a中间体的制备方法
Dyer Changes in behavior of mosses treated with ultrasound
RU96106615A (ru) Способ получения антигенов из культуральных бледных трепонем
KR20010071985A (ko) 세포의 촉매 활성을 증대시키는 방법
JPS5748918A (en) Antitumor substance
SU1514774A1 (ru) Штамм бактерий мокахееба брес1еб продуцент саит-специфической эндонуклеазы μ,,,αι
Leef et al. A cryobiological method for isolating fungal mutants

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties