ATE239073T1 - Hemmung des tumorzellwachstums durch verabreichung von b7-transfizierten zellen - Google Patents
Hemmung des tumorzellwachstums durch verabreichung von b7-transfizierten zellenInfo
- Publication number
- ATE239073T1 ATE239073T1 AT93307816T AT93307816T ATE239073T1 AT E239073 T1 ATE239073 T1 AT E239073T1 AT 93307816 T AT93307816 T AT 93307816T AT 93307816 T AT93307816 T AT 93307816T AT E239073 T1 ATE239073 T1 AT E239073T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- tumor cells
- tumor cell
- cell growth
- transfied
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title abstract 2
- 230000004565 tumor cell growth Effects 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 210000004881 tumor cell Anatomy 0.000 abstract 6
- 230000001900 immune effect Effects 0.000 abstract 3
- 102000018697 Membrane Proteins Human genes 0.000 abstract 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95612392A | 1992-10-02 | 1992-10-02 | |
| US610293A | 1993-01-15 | 1993-01-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239073T1 true ATE239073T1 (de) | 2003-05-15 |
Family
ID=26675186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93307816T ATE239073T1 (de) | 1992-10-02 | 1993-10-01 | Hemmung des tumorzellwachstums durch verabreichung von b7-transfizierten zellen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6183734B1 (de) |
| EP (1) | EP0600591B1 (de) |
| JP (1) | JP3837169B2 (de) |
| AT (1) | ATE239073T1 (de) |
| AU (1) | AU662450B2 (de) |
| CA (1) | CA2107537C (de) |
| DE (1) | DE69332921T2 (de) |
| DK (1) | DK0600591T3 (de) |
| ES (1) | ES2197147T3 (de) |
| MX (1) | MX9306147A (de) |
| PT (1) | PT600591E (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5056137A (en) * | 1989-09-27 | 1991-10-08 | Sills Richard R | Method and apparatus for encoding and decoding signals |
| US5858776A (en) * | 1993-11-03 | 1999-01-12 | Repligen Corporation | Tumor cells with increased immunogenicity and uses therefor |
| ATE221124T1 (de) * | 1994-12-30 | 2002-08-15 | Chiron Corp | Kombinationsvektoren zum austragen von genmaterial |
| EP0733373A3 (de) * | 1995-03-23 | 1999-04-28 | Bristol-Myers Squibb Company | Zusammensetzung und Verfahren zur Erhöhung der Tumorzellenimmunogenität durch Verabreichung von B7-CD2-transfizierten Zellen |
| WO1996034952A1 (de) * | 1995-05-04 | 1996-11-07 | Boehringer Ingelheim International Gmbh | Expression von tap und lmp in tumorzellen |
| DE19516040A1 (de) * | 1995-05-04 | 1996-11-07 | Boehringer Ingelheim Int | Expression TAP und LMP in Tumorzellen |
| SE9604581D0 (sv) * | 1996-12-12 | 1996-12-12 | Karolinska Innovations Ab | An agent against cancer and virus infections |
| US7235653B2 (en) | 1996-12-31 | 2007-06-26 | Isis Pharmaceuticals, Inc. | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
| US6319906B1 (en) | 1996-12-31 | 2001-11-20 | Isis Pharmaceuticals | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
| US6077833A (en) * | 1996-12-31 | 2000-06-20 | Isis Pharmaceuticals, Inc. | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
| US6682741B1 (en) * | 1998-06-10 | 2004-01-27 | The United States Of America As Represented By The Department Of Health And Human Services | β2 microglobulin fusion proteins and high affinity variants |
| AUPQ755300A0 (en) * | 2000-05-17 | 2000-06-08 | Monash University | Immune potentiating compositions |
| US20040136972A1 (en) * | 2001-09-07 | 2004-07-15 | Yeda Research And Development Co. Ltd. | Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues |
| US7780993B2 (en) * | 2001-09-07 | 2010-08-24 | Yeda Research And Development Co. Ltd. | Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts |
| US20030096016A1 (en) * | 2001-09-07 | 2003-05-22 | Yeda Research And Development Co. Ltd. | Methods of kidney transplantation utilizing developing nephric tissue |
| JP2005533015A (ja) * | 2002-05-02 | 2005-11-04 | ユニバーシティー オブ コネティカット ヘルス センター | 抗体療法の有効性を増強するための熱ショックタンパク質の使用 |
| IL165425A0 (en) * | 2004-11-28 | 2006-01-15 | Yeda Res & Dev | Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues |
| US20050070474A1 (en) * | 2003-04-28 | 2005-03-31 | Krissansen Geoffrey Wayne | Methods of treatment and compositions therefor |
| US20050090440A1 (en) * | 2003-04-28 | 2005-04-28 | Krissansen Geoffrey W. | Tumour treating combinations, compositions and methods |
| US7897582B2 (en) | 2003-05-23 | 2011-03-01 | Isis Pharmaceuticals, Inc. | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
| US7960355B2 (en) | 2003-05-23 | 2011-06-14 | Isis Pharmaceuticals, Inc. | Compositions and methods for the modulation of the expression of B7 protein |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06508501A (ja) * | 1990-07-02 | 1994-09-29 | ブリストル―マイアーズ スクイブ カンパニー | Ｂ細胞上のｃｄ２８レセプターに対するリガンドおよび該リガンドを用いた細胞間相互作用の調節方法 |
-
1993
- 1993-10-01 DE DE69332921T patent/DE69332921T2/de not_active Expired - Lifetime
- 1993-10-01 PT PT93307816T patent/PT600591E/pt unknown
- 1993-10-01 DK DK93307816T patent/DK0600591T3/da active
- 1993-10-01 ES ES93307816T patent/ES2197147T3/es not_active Expired - Lifetime
- 1993-10-01 CA CA002107537A patent/CA2107537C/en not_active Expired - Fee Related
- 1993-10-01 MX MX9306147A patent/MX9306147A/es unknown
- 1993-10-01 AT AT93307816T patent/ATE239073T1/de active
- 1993-10-01 EP EP93307816A patent/EP0600591B1/de not_active Expired - Lifetime
- 1993-10-04 JP JP24771693A patent/JP3837169B2/ja not_active Expired - Fee Related
- 1993-10-04 AU AU48772/93A patent/AU662450B2/en not_active Ceased
-
1995
- 1995-03-10 US US08/402,405 patent/US6183734B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6183734B1 (en) | 2001-02-06 |
| CA2107537C (en) | 2007-01-30 |
| EP0600591A3 (de) | 1995-03-01 |
| EP0600591A2 (de) | 1994-06-08 |
| MX9306147A (es) | 1994-06-30 |
| JPH0769928A (ja) | 1995-03-14 |
| AU662450B2 (en) | 1995-08-31 |
| JP3837169B2 (ja) | 2006-10-25 |
| DE69332921T2 (de) | 2004-05-19 |
| PT600591E (pt) | 2003-09-30 |
| EP0600591B1 (de) | 2003-05-02 |
| AU4877293A (en) | 1994-04-14 |
| CA2107537A1 (en) | 1994-04-03 |
| DE69332921D1 (de) | 2003-06-05 |
| DK0600591T3 (da) | 2003-08-25 |
| ES2197147T3 (es) | 2004-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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