ATE237136T1 - Assay, verbindungen, therapie und nachweisverfahren um zelluläre dns-reparatur- aktivität zu modulieren - Google Patents
Assay, verbindungen, therapie und nachweisverfahren um zelluläre dns-reparatur- aktivität zu modulierenInfo
- Publication number
- ATE237136T1 ATE237136T1 AT98900589T AT98900589T ATE237136T1 AT E237136 T1 ATE237136 T1 AT E237136T1 AT 98900589 T AT98900589 T AT 98900589T AT 98900589 T AT98900589 T AT 98900589T AT E237136 T1 ATE237136 T1 AT E237136T1
- Authority
- AT
- Austria
- Prior art keywords
- dna repair
- dna
- cellular dna
- assay
- therapy
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 108091092356 cellular DNA Proteins 0.000 title abstract 3
- 238000003556 assay Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 102000008158 DNA Ligase ATP Human genes 0.000 abstract 4
- 108010060248 DNA Ligase ATP Proteins 0.000 abstract 4
- 230000033616 DNA repair Effects 0.000 abstract 4
- 102100027828 DNA repair protein XRCC4 Human genes 0.000 abstract 3
- 101000649315 Homo sapiens DNA repair protein XRCC4 Proteins 0.000 abstract 3
- 230000003993 interaction Effects 0.000 abstract 3
- 102100022204 DNA-dependent protein kinase catalytic subunit Human genes 0.000 abstract 1
- 101710157074 DNA-dependent protein kinase catalytic subunit Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010038997 Retroviral infections Diseases 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/9015—Ligases (6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700574.8A GB9700574D0 (en) | 1997-01-13 | 1997-01-13 | Methods and means relating to retrotransposon and retroviral integration |
| GBGB9713131.2A GB9713131D0 (en) | 1997-06-20 | 1997-06-20 | Assays,therapeutic and diagnostic methods and means |
| PCT/GB1998/000095 WO1998030902A1 (en) | 1997-01-13 | 1998-01-13 | Assays, agents, therapy and diagnosis relating to modulation of cellular dna repair activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237136T1 true ATE237136T1 (de) | 2003-04-15 |
Family
ID=26310785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98900589T ATE237136T1 (de) | 1997-01-13 | 1998-01-13 | Assay, verbindungen, therapie und nachweisverfahren um zelluläre dns-reparatur- aktivität zu modulieren |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6753158B1 (de) |
| EP (1) | EP0966683B1 (de) |
| JP (1) | JP2001508868A (de) |
| AT (1) | ATE237136T1 (de) |
| AU (1) | AU724108B2 (de) |
| CA (1) | CA2277481A1 (de) |
| DE (1) | DE69813194T2 (de) |
| DK (1) | DK0966683T3 (de) |
| ES (1) | ES2197453T3 (de) |
| GB (1) | GB2322193B (de) |
| PT (1) | PT966683E (de) |
| WO (1) | WO1998030902A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6569681B1 (en) * | 2000-03-14 | 2003-05-27 | Transkaryotic Therapies, Inc. | Methods of improving homologous recombination |
| DE10161829B4 (de) * | 2001-12-15 | 2006-02-16 | Peter Lahnert | Neue Methode zur Bestimmung der Telomerlänge und ihre Verwendung zur Abschätzung des Lebensalters |
| CA2954578A1 (en) * | 2004-03-15 | 2005-09-29 | Sunesis Pharmaceuticals, Inc. | Methods of using sns-595 in treating cancer |
| US8580814B2 (en) | 2006-04-03 | 2013-11-12 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| MX2008015775A (es) | 2006-06-12 | 2009-04-17 | Sunesis Pharmaceuticals Inc | Compuestos y composiciones para tratamiento de cancer. |
| EP2625278A1 (de) * | 2010-10-08 | 2013-08-14 | Regents of the University of Minnesota | Verfahren zur erhöhung der gentargeting-frequenz |
| EP2983665A1 (de) * | 2013-03-15 | 2016-02-17 | The Regents of The University of California | Therapeutika und methoden zur behandlung von dns-reparaturmangelstörung |
| KR102202606B1 (ko) * | 2018-11-30 | 2021-01-15 | (주)바이오스플래시 | 바이오레티놀을 생산하는 미생물 및 이를 이용한 바이오레티놀의 생산방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994017189A2 (en) | 1993-01-21 | 1994-08-04 | The Salk Institute For Biological Studies | Protein kinases |
| AU7972594A (en) | 1993-10-12 | 1995-05-04 | Baylor College Of Medicine | Hepatitis b virus interacts with cellular dna repair processes |
| WO1996030524A1 (en) | 1995-03-31 | 1996-10-03 | Human Genome Sciences, Inc. | Human dna ligase iii |
-
1998
- 1998-01-13 GB GB9800663A patent/GB2322193B/en not_active Expired - Fee Related
- 1998-01-13 DK DK98900589T patent/DK0966683T3/da active
- 1998-01-13 EP EP98900589A patent/EP0966683B1/de not_active Expired - Lifetime
- 1998-01-13 WO PCT/GB1998/000095 patent/WO1998030902A1/en not_active Ceased
- 1998-01-13 ES ES98900589T patent/ES2197453T3/es not_active Expired - Lifetime
- 1998-01-13 AU AU55681/98A patent/AU724108B2/en not_active Ceased
- 1998-01-13 CA CA002277481A patent/CA2277481A1/en not_active Abandoned
- 1998-01-13 US US09/341,505 patent/US6753158B1/en not_active Expired - Fee Related
- 1998-01-13 AT AT98900589T patent/ATE237136T1/de not_active IP Right Cessation
- 1998-01-13 DE DE69813194T patent/DE69813194T2/de not_active Expired - Fee Related
- 1998-01-13 JP JP53067098A patent/JP2001508868A/ja not_active Ceased
- 1998-01-13 PT PT98900589T patent/PT966683E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001508868A (ja) | 2001-07-03 |
| US6753158B1 (en) | 2004-06-22 |
| AU724108B2 (en) | 2000-09-14 |
| AU5568198A (en) | 1998-08-03 |
| CA2277481A1 (en) | 1998-07-16 |
| EP0966683B1 (de) | 2003-04-09 |
| DE69813194D1 (de) | 2003-05-15 |
| DK0966683T3 (da) | 2003-08-04 |
| GB2322193A (en) | 1998-08-19 |
| PT966683E (pt) | 2003-08-29 |
| WO1998030902A1 (en) | 1998-07-16 |
| DE69813194T2 (de) | 2004-02-05 |
| ES2197453T3 (es) | 2004-01-01 |
| GB2322193B (en) | 1999-09-29 |
| GB9800663D0 (en) | 1998-03-11 |
| EP0966683A1 (de) | 1999-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Naudin et al. | A differential role for interleukin-6 and tumor necrosis factor-α in schizophrenia? | |
| IL147793A0 (en) | Optical system analysis of cells | |
| DK1131471T3 (da) | Et system til cellebaseret screening | |
| Hoerning et al. | Subsets of human CD4+ regulatory T cells express the peripheral homing receptor CXCR3 | |
| WO2000050872A3 (en) | A system for cell-based screening | |
| ES2053532T3 (es) | Metodos de inmunoensayo. | |
| Nakamachi et al. | Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts | |
| DK153886D0 (da) | Fastfasesystem til benyttelse i ligand-receptor analyser | |
| ZA877719B (en) | Immunoassay based on two enzyme inhibition system | |
| WO2000067037A3 (en) | A combined rapid anti-microbial susceptibility assay and microorganism identification system | |
| Tomoda et al. | Cytokine production and modulation: comparison of patients with chronic fatigue syndrome and normal controls | |
| ATE237136T1 (de) | Assay, verbindungen, therapie und nachweisverfahren um zelluläre dns-reparatur- aktivität zu modulieren | |
| Carlini et al. | Different susceptibility of T and B cells to cladribine depends on their levels of deoxycytidine kinase activity linked to activation status | |
| AR018821A1 (es) | Procedimiento para la determinacion de antibioticos con nucleo beta-lactama en un liquido biologico | |
| Hurwitz et al. | Induction of a calcium/calmodulin-dependent phosphodiesterase during phytohemagglutinin-stimulated lymphocyte mitogenesis. | |
| ATE234467T1 (de) | Immunoassay von vollblutproben | |
| ATE168781T1 (de) | Neue antikoagulant-cofaktor aktivität | |
| Maley et al. | Differential inhibition of host and viral thymidylate synthetases by folylpolyglutamates. | |
| Roberts et al. | Plasma purine nucleoside phosphorylase in cancer patients | |
| WO2003081206A3 (en) | Stratification of patient populations having or suspected of having rheumatoid arthritis | |
| KR860006039A (ko) | 췌장의 α-아밀라제를 정량하는 방법 및 시약 | |
| AU561326B2 (en) | Specific determination of pancreatic alpha amylase | |
| Bardos et al. | Anti-Tumour Activity of 5-Mercaptouracil | |
| Rossi et al. | Soluble interleukin‐2 receptor monitoring during bacterial and viral infections in liver transplant recipients: A comparative evaluation 1 | |
| BR9814866A (pt) | Uso de oligÈmeros de ácido poliamida nucléicopara produzir uma resposta biológica |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0966683 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |