ATE236646T1 - Reaktive sauerstoffverbindungen enthaltende verbindungen zur induzierung von zelldifferentiation maligner zellen so wie leukämie - Google Patents
Reaktive sauerstoffverbindungen enthaltende verbindungen zur induzierung von zelldifferentiation maligner zellen so wie leukämieInfo
- Publication number
- ATE236646T1 ATE236646T1 AT97946972T AT97946972T ATE236646T1 AT E236646 T1 ATE236646 T1 AT E236646T1 AT 97946972 T AT97946972 T AT 97946972T AT 97946972 T AT97946972 T AT 97946972T AT E236646 T1 ATE236646 T1 AT E236646T1
- Authority
- AT
- Austria
- Prior art keywords
- leukemia
- mammal
- reactive oxygen
- malignant cells
- compounds
- Prior art date
Links
- 208000032839 leukemia Diseases 0.000 title abstract 7
- 230000003211 malignant effect Effects 0.000 title abstract 2
- 230000024245 cell differentiation Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 150000002927 oxygen compounds Chemical class 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 8
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 201000011510 cancer Diseases 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 abstract 1
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 abstract 1
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 abstract 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3233296P | 1996-12-03 | 1996-12-03 | |
| PCT/CA1997/000930 WO1998024456A1 (en) | 1996-12-03 | 1997-12-02 | Reactive oxygen intermediates containing compounds effective in inducing cell differentiation of malignant cells such as leukemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236646T1 true ATE236646T1 (de) | 2003-04-15 |
Family
ID=21864379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97946972T ATE236646T1 (de) | 1996-12-03 | 1997-12-02 | Reaktive sauerstoffverbindungen enthaltende verbindungen zur induzierung von zelldifferentiation maligner zellen so wie leukämie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6399664B2 (de) |
| EP (1) | EP0951288B1 (de) |
| AT (1) | ATE236646T1 (de) |
| AU (1) | AU5218998A (de) |
| CA (1) | CA2274461A1 (de) |
| DE (1) | DE69720783D1 (de) |
| WO (1) | WO1998024456A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2377442A1 (en) * | 2002-03-20 | 2003-09-20 | Thomas Ichim | Increasing tumor oxygen content by administration of stressed cells |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| US7736494B2 (en) * | 2003-07-31 | 2010-06-15 | Acquisci, Inc. | Ozone delivery system including a variable pitch gas-fluid contact device |
| US20100318014A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of acute ischemic brain stroke with ozone |
| US20050189302A1 (en) * | 2003-07-31 | 2005-09-01 | Latino Joseph S. | Viral inactivation using ozone |
| WO2005025712A2 (en) * | 2003-07-31 | 2005-03-24 | Lipidviro Tech | Viral inactivation using ozone |
| US20100316727A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of inflammatory disorders with ozone |
| US20100316730A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of cardiovascular diseases with ozone |
| JP2007507528A (ja) * | 2003-10-03 | 2007-03-29 | ボストン,ジユデイス | 四量体酸素を含む方法、組成物、装置 |
| US8777889B2 (en) | 2004-06-15 | 2014-07-15 | Ceramatec, Inc. | Apparatus and method for administering a therapeutic agent into tissue |
| US8066659B2 (en) | 2004-06-15 | 2011-11-29 | Ceramatec, Inc. | Apparatus and method for treating and dispensing a material into tissue |
| US7615030B2 (en) * | 2003-10-06 | 2009-11-10 | Active O, Llc | Apparatus and method for administering a therapeutic agent into tissue |
| JP4384208B2 (ja) * | 2007-07-20 | 2009-12-16 | シャープ株式会社 | 外添剤の評価方法、トナーの評価方法 |
| US20170157317A1 (en) * | 2015-12-08 | 2017-06-08 | Priya Visweswaran Balakrishnan | Treatment Method to Cure Diseases Within a Patient by Administering Intravenous Oxygen Mixtures |
| US10335538B2 (en) * | 2015-12-08 | 2019-07-02 | Priya Visweswaran Balakrishnan | System and treatment method to increase circulation and pluripotency of stem and progenitor cells within a patient |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4632980A (en) | 1985-04-03 | 1986-12-30 | Immunologics | Ozone decontamination of blood and blood products |
| DE3940389A1 (de) * | 1989-12-06 | 1991-06-13 | Abolghassem Prof Dr M Pakdaman | Therapeutisches mittel |
| US5622848A (en) * | 1990-05-23 | 1997-04-22 | Medical Discoveries, Inc. | Electrically hydrolyzed salines as microbiocides for in vitro treatment of contaminated fluids containing blood |
| DE4100782A1 (de) * | 1991-01-12 | 1992-07-16 | Patentverwertung Dr J Haensler | Waessrige ozonpraeparate, verfahren zu ihrer herstellung und ihre verwendung |
| US5591457A (en) * | 1992-02-07 | 1997-01-07 | Vasogen Inc | Method of inhibiting the aggregation of blood platelets and stimulating the immune systems of a human |
-
1997
- 1997-12-02 AT AT97946972T patent/ATE236646T1/de not_active IP Right Cessation
- 1997-12-02 AU AU52189/98A patent/AU5218998A/en not_active Abandoned
- 1997-12-02 WO PCT/CA1997/000930 patent/WO1998024456A1/en not_active Ceased
- 1997-12-02 DE DE69720783T patent/DE69720783D1/de not_active Expired - Lifetime
- 1997-12-02 EP EP97946972A patent/EP0951288B1/de not_active Expired - Lifetime
- 1997-12-02 CA CA002274461A patent/CA2274461A1/en not_active Abandoned
- 1997-12-03 US US08/984,619 patent/US6399664B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2274461A1 (en) | 1998-06-11 |
| WO1998024456A1 (en) | 1998-06-11 |
| US20010049395A1 (en) | 2001-12-06 |
| AU5218998A (en) | 1998-06-29 |
| DE69720783D1 (de) | 2003-05-15 |
| EP0951288A1 (de) | 1999-10-27 |
| US6399664B2 (en) | 2002-06-04 |
| EP0951288B1 (de) | 2003-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |