ATE236246T1 - Analytisches element, zusammensetzung und verfahren unter verwendung von modifizierter apo- meerrettich-peroxidase - Google Patents

Analytisches element, zusammensetzung und verfahren unter verwendung von modifizierter apo- meerrettich-peroxidase

Info

Publication number
ATE236246T1
ATE236246T1 AT95305007T AT95305007T ATE236246T1 AT E236246 T1 ATE236246 T1 AT E236246T1 AT 95305007 T AT95305007 T AT 95305007T AT 95305007 T AT95305007 T AT 95305007T AT E236246 T1 ATE236246 T1 AT E236246T1
Authority
AT
Austria
Prior art keywords
apo
peroxidase
hemoglobin
horserad
composition
Prior art date
Application number
AT95305007T
Other languages
English (en)
Inventor
Roy Eugene Snoke
Original Assignee
Johnson & Johnson Clin Diag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Clin Diag filed Critical Johnson & Johnson Clin Diag
Application granted granted Critical
Publication of ATE236246T1 publication Critical patent/ATE236246T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/962Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT95305007T 1994-07-19 1995-07-18 Analytisches element, zusammensetzung und verfahren unter verwendung von modifizierter apo- meerrettich-peroxidase ATE236246T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27739194A 1994-07-19 1994-07-19

Publications (1)

Publication Number Publication Date
ATE236246T1 true ATE236246T1 (de) 2003-04-15

Family

ID=23060663

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95305007T ATE236246T1 (de) 1994-07-19 1995-07-18 Analytisches element, zusammensetzung und verfahren unter verwendung von modifizierter apo- meerrettich-peroxidase

Country Status (7)

Country Link
US (1) US5776714A (de)
EP (1) EP0693552B1 (de)
JP (1) JP3715348B2 (de)
AT (1) ATE236246T1 (de)
AU (1) AU697785B2 (de)
CA (1) CA2154013C (de)
DE (1) DE69530148T2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19628484A1 (de) * 1996-07-15 1998-01-22 Boehringer Mannheim Gmbh Blutersatzmittel-Entstörung durch Peroxide
CA2270797A1 (en) * 1998-07-27 2000-01-27 Bayer Corporation Transparent flow through membrane for dry reagent analytical devices
EP1307741A4 (de) * 2000-07-26 2005-11-23 Biodiagnostics Inc Verfahren zur diagnose von thyroidparametern und zum überwachen von thyroxintherapien
US7183119B2 (en) * 2004-11-15 2007-02-27 Eastman Kodak Company Method for sensitive detection of multiple biological analytes
US7348147B2 (en) * 2004-11-15 2008-03-25 Carestream Health, Inc. Method and system for nucleic acid detection
US7074622B2 (en) * 2004-11-15 2006-07-11 Eastman Kodak Company Method and system for sorting and separating particles
WO2008019693A2 (en) * 2006-08-17 2008-02-21 Atonomics A/S Bio surface acoustic wave (saw) resonator amplification for detection of a target analyte
US8008035B2 (en) * 2007-01-25 2011-08-30 Roche Diagnostics Operations, Inc. Enhancement of vanadium-containing phosphatase inhibitors
EP1949894B1 (de) * 2007-01-25 2016-06-29 Roche Diagnostics GmbH Verstärkung von vanadiumhaltigen Phosphatasehemmern mit Polyole
CN111518780B (zh) * 2020-06-04 2022-06-14 郑州伊美诺生物技术有限公司 脱辅基辣根过氧化物酶的制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992158A (en) 1973-08-16 1976-11-16 Eastman Kodak Company Integral analytical element
US3905872A (en) 1973-12-14 1975-09-16 American Cyanamid Co Alkaline phosphatase test material
US4089747A (en) 1976-08-09 1978-05-16 Eastman Kodak Company Compositions for the detection of hydrogen peroxide
US4376165A (en) * 1978-06-22 1983-03-08 Miles Laboratories, Inc. Method of preparing an enzyme-labeled ligand for use in specific binding assays and the labeled conjugate produced thereby
US4258001A (en) 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
JPS55164356A (en) 1979-06-08 1980-12-22 Fuji Photo Film Co Ltd Multi-layer analysis sheet for liquid sample analysis
JPS6021370B2 (ja) 1979-11-05 1985-05-27 富士写真フイルム株式会社 写真感光材料
JPS5767860A (en) 1980-10-15 1982-04-24 Fuji Photo Film Co Ltd Material for multilayer analysis
JPS57101761A (en) 1980-12-17 1982-06-24 Konishiroku Photo Ind Co Ltd Analyzing element
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
JPS57200862A (en) 1981-06-05 1982-12-09 Fuji Photo Film Co Ltd Mutilayer analysis element utilizing unique binding reaction
JPS5845557A (ja) 1981-09-14 1983-03-16 Yatoron:Kk 過酸化水素定量用試薬
DE3225331A1 (de) 1982-07-07 1984-01-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung von direktem und gesamt-bilirubin sowie hierfuer geeignetes reagens
JPS5925699A (ja) 1982-08-03 1984-02-09 Torii Yakuhin Kk 酵素活性測定方法
EP0116454B1 (de) 1983-02-11 1987-04-29 National Research Development Corporation Erhöhte lumineszierende oder luminometrische Prüfung
JPS59193352A (ja) 1983-04-18 1984-11-01 Fuji Photo Film Co Ltd 分析試薬および多層化学分析要素
US4670385A (en) 1984-05-21 1987-06-02 Eastman Kodak Company Compositions and elements containing triarylmethane leuco dyes and methods using same
GB8420053D0 (en) 1984-08-07 1984-09-12 Secr Social Service Brit Enhanced luminescent/luminometric assay
GB8514288D0 (en) * 1985-06-06 1985-07-10 Amersham Int Plc Enzyme assay of body fluids
US4670381A (en) 1985-07-19 1987-06-02 Eastman Kodak Company Heterogeneous immunoassay utilizing horizontal separation in an analytical element
US4828983A (en) 1986-07-10 1989-05-09 Eastman Kodak Company Use of phenols and anilines to increase the rate of peroxidase catalyzed oxidation of leuco dyes
US4997772A (en) 1987-09-18 1991-03-05 Eastman Kodak Company Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use
US4828978A (en) 1987-09-18 1989-05-09 Eastman Kodak Company Agglutination reagent and method of preparing same
US5177023A (en) 1987-08-03 1993-01-05 Eastman Kodak Company Water-insoluble reagent elements containing same and methods of use
US4892817A (en) 1987-09-21 1990-01-09 Biogenex Laboratories Stable phosphatase substrate composition
ATE137805T1 (de) 1989-02-14 1996-05-15 Wako Pure Chem Ind Ltd Verfahren zur erhöhung von chemilumineszenz
US5162219A (en) 1990-06-18 1992-11-10 Eastman Kodak Company Preparation of amine-enriched proteins having an increased isoelectric point
US5147777A (en) 1990-06-18 1992-09-15 Eastman Kodak Company Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use
EP0517327B1 (de) 1991-06-07 2001-08-16 Johnson & Johnson Clinical Diagnostics, Inc. Immunoassays unter Verwendung von markierten Hapten-Analogen
CA2062176A1 (en) 1991-06-07 1992-12-08 Glen M. Dappen Use of the gravure process for coating thin film layers
US5958339A (en) * 1992-08-31 1999-09-28 Clinical Diagnostic Systems, Inc. Format for immunoassay in thin film
US5372932A (en) 1992-12-22 1994-12-13 Eastman Kodak Company Analytical element and method for the determination of a specific binding ligand using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer

Also Published As

Publication number Publication date
US5776714A (en) 1998-07-07
JPH08170961A (ja) 1996-07-02
DE69530148T2 (de) 2004-01-08
EP0693552A2 (de) 1996-01-24
CA2154013A1 (en) 1996-01-20
DE69530148D1 (de) 2003-05-08
AU697785B2 (en) 1998-10-15
EP0693552B1 (de) 2003-04-02
EP0693552A3 (de) 1996-04-03
JP3715348B2 (ja) 2005-11-09
AU2492695A (en) 1996-02-01
CA2154013C (en) 2006-12-19

Similar Documents

Publication Publication Date Title
DE69823985D1 (de) Nachweis der krankheitsbedingten konformation eines proteins
DE69530148D1 (de) Analytisches Element, Zusammensetzung und Verfahren unter Verwendung von modifizierter Apo-Meerrettich-Peroxidase
DE69429192T2 (de) Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen
ATE144840T1 (de) Homogene immunotests unter verwendung von enzym- inhibitoren
DE69132238T2 (de) Verfahren zur Stabilisierung von Enzym-Konjugaten
DE69224231T2 (de) Verfahren und Zusammensetzungen für Enzymkomplimentationassays unter Verwendung der Omega-Region der Beta-Galactosidase
PT85992A (de) Verfahren zur bestimmung von anti-hiv, mittel dazu und ihre verwendung in diesem verfahren
ATE284034T1 (de) Verfahren zum nachweis von protein s
ATE191568T1 (de) Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
Manabe et al. Identification of bovine fetal and adult serum/plasma proteins by two‐dimensional electrophoresis and immunochemical staining
ATE36557T1 (de) Verfahren zur bestimmung der wirksamkeit von substraten oder enzymen.
Vilanova et al. Urea‐gradient gel electrophoresis studies on the association of procarboxypeptidases A and B, proproteinase E, and their tryptic activation products
DE3751249T2 (de) Protein L und ihre Untereinheiten, mit immunglobulinbindender Aktivität, Verfahren zur Herstellung, Reagenssatz, pharmazeutische Zubereitung und ein Peptococcus-magnus-Stamm.
DE3851304D1 (de) Verfahren und Testzusammensetzung zur Bestimmung von Enzym-Aktivität.
Chang et al. Characterization of bovine collagens using capillary electrophoresis—an alternative to slab gel electrophoresis
DK0445626T3 (da) Funktionel test til bestemmelse af protein S-aktivitet.
ATE64470T1 (de) Verfahren und zusammensetzungen zur bestimmung von heparin.
ATE242883T1 (de) Verfahren zur bestimmung von blutgerinnungsfaktoren viii und ix
CA2114163C (en) Method for stabilizing antigenicity of myeloperoxidase
Bantjes et al. Preferential adsorption of high density lipoprotein (HDL) in blood plasma/polymer interaction
DE3783840T2 (de) Verfahren zur bestimmung von plasma-protein und testsatz dafuer.
DE59710696D1 (de) Verfahren zum vergleichenden screenen von substanzen mit pharmakologischer wirkung
Feddersen et al. γ-Dimerization, α-Polymerization, and Plasmin Degradation of Human Fibrin
DK160689D0 (da) Fremgangsmaade til paavisning af et specifikt bindingsstof i blod og proeveudstyr til udfoerelse af fremgangsmaaden
SE9203159D0 (sv) Partikel suspension

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties