ATE235032T1 - Tieftemperaturspeicher für spin-polarisiertes xenon-129 - Google Patents

Tieftemperaturspeicher für spin-polarisiertes xenon-129

Info

Publication number
ATE235032T1
ATE235032T1 AT97917656T AT97917656T ATE235032T1 AT E235032 T1 ATE235032 T1 AT E235032T1 AT 97917656 T AT97917656 T AT 97917656T AT 97917656 T AT97917656 T AT 97917656T AT E235032 T1 ATE235032 T1 AT E235032T1
Authority
AT
Austria
Prior art keywords
hyperpolarized
accumulation
spin
low temperature
temperature storage
Prior art date
Application number
AT97917656T
Other languages
English (en)
Inventor
Gordon D Cates Jr
Bastiaan Driehuys
William Happer
Eli Miron
Brian Saam
Drive Brookings
Daniel Walter
Original Assignee
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Princeton filed Critical Univ Princeton
Application granted granted Critical
Publication of ATE235032T1 publication Critical patent/ATE235032T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • C01B23/001—Purification or separation processes of noble gases
    • C01B23/0036—Physical processing only
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J3/00—Processes or apparatus for separating the constituents of gaseous or liquefied gaseous mixtures involving the use of liquefaction or solidification
    • F25J3/06—Processes or apparatus for separating the constituents of gaseous or liquefied gaseous mixtures involving the use of liquefaction or solidification by partial condensation
    • F25J3/063—Processes or apparatus for separating the constituents of gaseous or liquefied gaseous mixtures involving the use of liquefaction or solidification by partial condensation characterised by the separated product stream
    • F25J3/0685—Processes or apparatus for separating the constituents of gaseous or liquefied gaseous mixtures involving the use of liquefaction or solidification by partial condensation characterised by the separated product stream separation of noble gases
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/02—Molecular or atomic beam generation
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B2210/00—Purification or separation of specific gases
    • C01B2210/0029—Obtaining noble gases
    • C01B2210/0037—Xenon
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2205/00—Processes or apparatus using other separation and/or other processing means
    • F25J2205/20—Processes or apparatus using other separation and/or other processing means using solidification of components
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2210/00—Processes characterised by the type or other details of the feed stream
    • F25J2210/42—Nitrogen
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2215/00—Processes characterised by the type or other details of the product stream
    • F25J2215/36—Xenon
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2270/00—Refrigeration techniques used
    • F25J2270/60—Closed external refrigeration cycle with single component refrigerant [SCR], e.g. C1-, C2- or C3-hydrocarbons
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2270/00—Refrigeration techniques used
    • F25J2270/90—External refrigeration, e.g. conventional closed-loop mechanical refrigeration unit using Freon or NH3, unspecified external refrigeration
    • F25J2270/904—External refrigeration, e.g. conventional closed-loop mechanical refrigeration unit using Freon or NH3, unspecified external refrigeration by liquid or gaseous cryogen in an open loop
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25J—LIQUEFACTION, SOLIDIFICATION OR SEPARATION OF GASES OR GASEOUS OR LIQUEFIED GASEOUS MIXTURES BY PRESSURE AND COLD TREATMENT OR BY BRINGING THEM INTO THE SUPERCRITICAL STATE
    • F25J2290/00—Other details not covered by groups F25J2200/00 - F25J2280/00
    • F25J2290/62—Details of storing a fluid in a tank
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S62/00—Refrigeration
    • Y10S62/919—Isotope
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S62/00—Refrigeration
    • Y10S62/923—Inert gas
    • Y10S62/925—Xenon or krypton

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Image Processing (AREA)
AT97917656T 1996-03-29 1997-03-27 Tieftemperaturspeicher für spin-polarisiertes xenon-129 ATE235032T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/622,865 US5809801A (en) 1996-03-29 1996-03-29 Cryogenic accumulator for spin-polarized xenon-129
PCT/US1997/005004 WO1997037177A1 (en) 1996-03-29 1997-03-27 Cryogenic accumulator for spin-polarized xenon-129

Publications (1)

Publication Number Publication Date
ATE235032T1 true ATE235032T1 (de) 2003-04-15

Family

ID=24495803

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97917656T ATE235032T1 (de) 1996-03-29 1997-03-27 Tieftemperaturspeicher für spin-polarisiertes xenon-129

Country Status (10)

Country Link
US (2) US5809801A (de)
EP (1) EP0890066B1 (de)
JP (2) JP2000507688A (de)
AT (1) ATE235032T1 (de)
AU (1) AU712530B2 (de)
CA (1) CA2250167C (de)
DE (1) DE69719962T2 (de)
DK (1) DK0890066T3 (de)
ES (1) ES2195131T3 (de)
WO (1) WO1997037177A1 (de)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
BR9711082A (pt) * 1996-03-29 2000-01-11 Lawrence Berkeley National Lab Realce de rmn emri na presença de gases mopbres hiperpolarizados.
US6085743A (en) * 1997-05-30 2000-07-11 The Regent Of The University Of Michigan Polarized gas delivery system/method
EP1015086B1 (de) * 1997-08-18 2007-07-04 The Trustees Of Princeton University Spin-polarisation eines edelgases über spinaustausch mit optisch gepumpten alkalimetallen
ES2201572T3 (es) 1997-12-12 2004-03-16 Medi-Physics, Inc. Procedimientos de descongelacion y recuperacion de los gases polarizados.
AU2003203796B2 (en) * 1997-12-12 2006-10-12 Medi-Physics, Inc. Polarized gas accumulators and heating jackets and associated gas collection and thaw methods and polarized gas products
US6079213A (en) * 1997-12-12 2000-06-27 Magnetic Imaging Technologies Incorporated Methods of collecting, thawing, and extending the useful life of polarized gases and associated accumulators and heating jackets
US6346229B1 (en) 1998-03-18 2002-02-12 Medi-Physics, Inc. Methods for imaging pulmonary and cardiac vasculature and evaluating blood flow using dissolved polarized 129Xe
US6051208A (en) * 1998-04-13 2000-04-18 Duke University In vivo magnetic resonance vascular imaging using laser-polarized gas microbubbles
US6423387B1 (en) 1998-06-17 2002-07-23 Medi-Physics, Inc. Resilient containers for hyperpolarized gases and associated methods
JP2002518652A (ja) 1998-06-17 2002-06-25 メディ‐フィジクス，インコーポレイテッド 過分極化されたガスのための弾性容器
BR9911346A (pt) * 1998-06-17 2001-03-13 Medi Physics Inc Dispositivo de transporte de gás hiperpolarizado e método de transporte associado
US6237363B1 (en) 1998-09-30 2001-05-29 Medi-Physics, Inc. Hyperpolarized noble gas extraction methods masking methods and associated transport containers
US6523356B2 (en) 1998-09-30 2003-02-25 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6286319B1 (en) 1998-09-30 2001-09-11 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6125654A (en) * 1998-10-16 2000-10-03 Syracuse University Bulk production and usage of hyperpolarized 129 Xenon
US6284222B1 (en) 1998-11-03 2001-09-04 Medi--Physics, Inc. Hyperpolarized helium-3 microbubble gas entrapment methods
WO2000050914A1 (en) * 1999-02-23 2000-08-31 Medi-Physics, Inc. Portable system for monitoring the polarization level of a hyperpolarized gas during transport
US6408849B1 (en) * 1999-06-18 2002-06-25 Aeronex, Inc. Recovery and purification of gases used in medical processes
US6295834B1 (en) * 1999-06-30 2001-10-02 Medi-Physics, Inc. NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production
US6611540B1 (en) 1999-07-29 2003-08-26 Otward Maria Mueller Diode-laser system for hyperpolarized He-3 and Xe-129 gas generation and other applications
DE19937566C2 (de) * 1999-08-09 2001-06-28 Forschungszentrum Juelich Gmbh Hochdruckpolarisator für Edelgase und Verfahren zum Betreiben des Polarisators
US6648130B1 (en) * 1999-08-11 2003-11-18 Medi-Physics, Inc. Hyperpolarized gas transport and storage devices and associated transport and storage methods using permanent magnets
US6868099B1 (en) * 1999-11-04 2005-03-15 Wisconsin Alumni Research Foundation Frequency-narrowed high power diode laser system with external cavity
DE10000675C2 (de) 2000-01-11 2001-11-15 Otten Ernst Wilhelm Lineardurchführung, Vorrichtung und Verfahren zur hochproduktiven Erzeugung von hoch kernspinpolarisiertem Helium-3 Gas
GB0001727D0 (en) * 2000-01-25 2000-03-15 Oxford Instr Uk Ltd Hyperpolarization of a noble gas
JP2003526437A (ja) 2000-03-13 2003-09-09 メディ−フィジックス・インコーポレイテッド ガス状過分極１２９Ｘｅの直接注射を使用する診断処置並びに関連するシステムおよび生成物
WO2002005709A2 (en) * 2000-07-13 2002-01-24 Medi-Physics, Inc. Diagnostic procedures using 129xe spectroscopy characteristic chemical shift to detect pathology in vivo
US6444984B1 (en) 2000-08-11 2002-09-03 Drs Sensors & Targeting Systems, Inc. Solid cryogenic optical filter
US6584133B1 (en) 2000-11-03 2003-06-24 Wisconsin Alumni Research Foundation Frequency-narrowed high power diode laser array method and system
IL155475A0 (en) * 2000-11-03 2003-11-23 Amersham Health As Methods and devices for polarised nmr samples
WO2002085417A2 (en) 2001-04-24 2002-10-31 Medi-Physics, Inc. Methods and devices for moisturizing hyperpolarized noble gases and pharmaceutical products thereof
EP1417437A1 (de) * 2001-08-17 2004-05-12 Medi-Physics, Inc. Magnetisches feld für auf tieftemperatur gespeichertes polarisiertes xenon129
US7179450B2 (en) * 2001-09-20 2007-02-20 Medi-Physics, Inc. Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
CA2463910A1 (en) * 2001-10-22 2003-05-01 Medi-Physics, Inc. Optical pumping modules, polarized gas blending and dispensing systems, and automated polarized gas distribution systems and related devices and methods
WO2003036316A1 (en) * 2001-10-22 2003-05-01 Medi-Physics Inc. Automated modular hyperpolarizers
US6846576B1 (en) 2002-04-10 2005-01-25 Seagate Technology Llc Coupling enhancement for medium with anti-ferromagnetic coupling
AU2003269207A1 (en) * 2002-05-16 2003-12-02 Medi-Physics, Inc Methods and systems for determining polarization of a gas based on electron paramagnetic resonance
AU2003248529A1 (en) * 2002-05-17 2003-12-02 Medi-Physics, Inc Methods, systems, circuits, and computer program products for determining polarization of a gas
EP1534990B1 (de) * 2002-07-23 2006-10-25 Medi-Physics, Inc. Automatisierte dynamische druckempfindliche systeme zur abgabe von hyperpolarisiertem gas und zugehörige verfahren und rechnerprogrammprodukte
EP1573349A1 (de) * 2002-12-20 2005-09-14 Medi-Physics, Inc. Kalibrierung einer polarisationsmessstation
JP3998243B2 (ja) * 2003-01-10 2007-10-24 東横化学株式会社 核スピン偏極キセノンガスの製造方法及び製造装置
KR20050088359A (ko) * 2003-01-17 2005-09-05 메디-피직스, 인크. 광학 펌핑되는 초분극된 가스 제조 방법
CN1777454A (zh) * 2003-04-22 2006-05-24 医疗物理有限公司 用于呼吸和超极化气体输送的mri/nmr兼容的潮气量控制和测量系统、方法和装置
JP3978159B2 (ja) 2003-07-03 2007-09-19 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー 磁気共鳴撮像システム
WO2005069027A1 (de) 2004-01-19 2005-07-28 Forschungszentrum Jülich GmbH Verfahren zur hyperpolarisation von atomkernen und vorrichtung zur durchführung des verfahrens
DE102004002639A1 (de) * 2004-01-19 2005-09-15 Forschungszentrum Jülich GmbH Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens
DE102004023345B4 (de) * 2004-01-19 2006-11-09 Forschungszentrum Jülich GmbH Verfahren zur Hyperpolarisation von Atomkernen und Vorrichtung zur Durchführung des Verfahrens
EP1766309B1 (de) * 2004-04-21 2018-10-03 University Of New Hampshire Verfahren und vorrichtung zum sammeln von hyperpolarisiertem xenon
AU2007254464B2 (en) 2006-02-21 2013-02-21 Avrum Belzer Hyperpolarization methods, systems and compositions
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US8456161B2 (en) * 2006-09-05 2013-06-04 The Trustees Of Princeton University Polarizing nuclei solids via spin transfer from an optically-pumped alkali vapor
US7928359B2 (en) * 2006-09-20 2011-04-19 University Of New Hampshire Thermal management technology for polarizing Xenon
US8405022B2 (en) 2006-09-20 2013-03-26 University Of New Hampshire Thermal management technology for polarizing xenon
BRPI0718198A2 (pt) * 2006-10-03 2013-11-12 Univ Duke Método para fornecer dados de mri de estado de troca gasosa pulmonar e/ou de barreira capilar-alveolar, sistema e dispositivo de varredura de mri, e, produto de programa de computador
US20080240998A1 (en) * 2007-03-28 2008-10-02 Urbahn John A Fluid path system for dissolution and transport of a hyperpolarized material
US8731640B2 (en) 2007-03-28 2014-05-20 General Electric Company Fluid path system for dissolution and transport of a hyperpolarized material
US8763410B2 (en) * 2008-04-21 2014-07-01 General Electric Company Method and apparatus for the dissolution and filtration of a hyperpolarized agent with a neutral dissolution media
WO2009143368A2 (en) * 2008-05-23 2009-11-26 University Of Utah Non-cryogenic storage cell for hyperpolarized 129xe
EP2309283B1 (de) * 2008-08-01 2012-09-19 Osaka University Verfahren zur konzentration von polarisiertem xenon, vorrichtung zur förderung von polarisiertem xenon und mrt-system
DE102008063703B3 (de) * 2008-12-19 2010-06-17 Bruker Biospin Ag Automatische Transportvorrichtung für NMR-Messproben, Kryomagnetsystem mit automatischer Transportvorrichtung, Transportbehälter für automatische Transportvorrichtung und Verfahren zum Befördern einer NMR-Messprobe
US8329122B1 (en) * 2009-07-01 2012-12-11 The United States Of America, As Represented By The Department Of Energy Method for production of an isotopically enriched compound
IN2012DN02418A (de) * 2009-08-31 2015-08-21 Millikelvin Technologies Llc
US9080710B2 (en) 2011-01-21 2015-07-14 Hamilton Sundstrand Corporation Accumulator reservoir venting
FR2988857B1 (fr) * 2012-03-30 2015-02-20 Commissariat Energie Atomique Procede de determination de la resistance cellulaire aux medicaments.
WO2015127208A1 (en) 2014-02-21 2015-08-27 1/1Duke University Hyperpolarized noble gas production systems with nanocluster suppression, detection and/or filtering and related methods and devices
US10126438B2 (en) 2014-09-19 2018-11-13 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
CN104921726B (zh) * 2015-05-26 2017-12-19 中国科学院武汉物理与数学研究所 一种用于超极化氙收集的液氮液位控制和显示装置
US11754652B2 (en) 2016-09-15 2023-09-12 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
US20200261606A1 (en) * 2017-10-06 2020-08-20 University Of Florida Research Foundation, Inc. Methods and systems for producing, using, and administering hyperpolarized fluids
US11944424B2 (en) 2018-05-18 2024-04-02 Duke University Dynamic 129Xe gas exchange spectroscopy
US11148833B1 (en) 2018-05-21 2021-10-19 Space Systems/Loral, Llc Spacecraft propellant management system
CN114644322B (zh) * 2022-04-15 2024-02-06 宁波诺丁汉大学 超极化稀有气体生产设备

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3748864A (en) * 1969-01-21 1973-07-31 Airco Inc Process for recovery and containment of radioactive gases
DE2426764C2 (de) * 1974-06-01 1981-07-09 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zum Abtrennen von Krypton aus einem radioaktiven Abgasgemisch und Gastrennanlage zum Durchführen des Verfahrens
US4417909A (en) * 1978-12-04 1983-11-29 Airco, Inc. Gas separation process
US4369048A (en) * 1980-01-28 1983-01-18 Dallas T. Pence Method for treating gaseous effluents emitted from a nuclear reactor
US4599462A (en) * 1983-05-25 1986-07-08 University Of Utah Methods for making solid solutions from normally immiscible components and for modifying the surface structure of solid materials
DE3518283C2 (de) * 1985-05-22 1994-09-22 Messer Griesheim Gmbh Verfahren zur Entfernung leichter flüchtiger Verunreinigungen aus Gasen
US4971258A (en) * 1988-08-26 1990-11-20 Ihi Master Metal Ltd. Method of making high-purity fine particles of reactive metals and manufacturing vessel therefor
US5039500A (en) * 1988-11-18 1991-08-13 Kyodo Oxygen Co., Ltd. Process for producing xenon
US4977749A (en) * 1989-04-25 1990-12-18 Sercel Jeffrey P Apparatus and method for purification of gases used in exciplex (excimer) lasers
US5161382A (en) * 1991-05-24 1992-11-10 Marin Tek, Inc. Combined cryosorption/auto-refrigerating cascade low temperature system
US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
US5617860A (en) * 1995-06-07 1997-04-08 Smithsonian Astrophysical Observatory Method and system for producing polarized 129 Xe gas
US5626137A (en) * 1995-10-02 1997-05-06 General Electric Company Apparatus and methods for magnetic resonance (MR) angiography using fluids polarized at low temperatures
BR9711082A (pt) * 1996-03-29 2000-01-11 Lawrence Berkeley National Lab Realce de rmn emri na presença de gases mopbres hiperpolarizados.

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AU2592097A (en) 1997-10-22
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EP0890066A1 (de) 1999-01-13
JP4231533B2 (ja) 2009-03-04
AU712530B2 (en) 1999-11-11
US5860295A (en) 1999-01-19
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