ATE223424T1 - Quinazolinon-verbindungen - Google Patents

Quinazolinon-verbindungen

Info

Publication number
ATE223424T1
ATE223424T1 AT98902115T AT98902115T ATE223424T1 AT E223424 T1 ATE223424 T1 AT E223424T1 AT 98902115 T AT98902115 T AT 98902115T AT 98902115 T AT98902115 T AT 98902115T AT E223424 T1 ATE223424 T1 AT E223424T1
Authority
AT
Austria
Prior art keywords
phosphate
alkyl
optionally substituted
compounds
derivative
Prior art date
Application number
AT98902115T
Other languages
English (en)
Inventor
Roger John Griffin
Alan Hilary Calvert
Nicola Jane Curtin
David Richard Newell
Bernard Thomas Golding
Original Assignee
Univ Newcastle Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Newcastle Ventures Ltd filed Critical Univ Newcastle Ventures Ltd
Application granted granted Critical
Publication of ATE223424T1 publication Critical patent/ATE223424T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
    • C07F9/65128—Six-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT98902115T 1997-02-01 1998-01-30 Quinazolinon-verbindungen ATE223424T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9702701.5A GB9702701D0 (en) 1997-02-01 1997-02-01 Quinazolinone compounds
PCT/GB1998/000303 WO1998033802A1 (en) 1997-02-01 1998-01-30 Quinazolinone compounds

Publications (1)

Publication Number Publication Date
ATE223424T1 true ATE223424T1 (de) 2002-09-15

Family

ID=10807378

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98902115T ATE223424T1 (de) 1997-02-01 1998-01-30 Quinazolinon-verbindungen

Country Status (10)

Country Link
US (1) US6156739A (de)
EP (1) EP0966476B1 (de)
JP (1) JP2001511776A (de)
KR (1) KR20000070467A (de)
AT (1) ATE223424T1 (de)
AU (1) AU5873998A (de)
CA (1) CA2278290C (de)
DE (1) DE69807661D1 (de)
GB (1) GB9702701D0 (de)
WO (1) WO1998033802A1 (de)

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CN102675221A (zh) 2005-09-16 2012-09-19 武田药品工业株式会社 用于制备嘧啶二酮衍生物的方法中的中间体
JP5221368B2 (ja) 2005-11-14 2013-06-26 サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク（セエヌエールエス） Ｐａｒｐ活性のインヒビター及びその使用
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CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
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CN103228141B (zh) * 2010-09-03 2016-04-20 拜耳知识产权有限责任公司 取代的稠合的嘧啶酮和二氢嘧啶酮
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GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues

Also Published As

Publication number Publication date
KR20000070467A (ko) 2000-11-25
CA2278290A1 (en) 1998-08-06
US6156739A (en) 2000-12-05
JP2001511776A (ja) 2001-08-14
EP0966476B1 (de) 2002-09-04
WO1998033802A1 (en) 1998-08-06
DE69807661D1 (de) 2002-10-10
GB9702701D0 (en) 1997-04-02
AU5873998A (en) 1998-08-25
CA2278290C (en) 2005-05-10
EP0966476A1 (de) 1999-12-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties