ATE223059T1 - Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin - Google Patents
Cyanidfreies reagens und verfahren zur bestimmung von hämoglobinInfo
- Publication number
- ATE223059T1 ATE223059T1 AT95912800T AT95912800T ATE223059T1 AT E223059 T1 ATE223059 T1 AT E223059T1 AT 95912800 T AT95912800 T AT 95912800T AT 95912800 T AT95912800 T AT 95912800T AT E223059 T1 ATE223059 T1 AT E223059T1
- Authority
- AT
- Austria
- Prior art keywords
- reagent
- cyanide
- blood sample
- group
- free
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 5
- 102000001554 Hemoglobins Human genes 0.000 title abstract 2
- 108010054147 Hemoglobins Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 2
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
- 238000002835 absorbance Methods 0.000 abstract 1
- RRUDCFGSUDOHDG-UHFFFAOYSA-N acetohydroxamic acid Chemical compound CC(O)=NO RRUDCFGSUDOHDG-UHFFFAOYSA-N 0.000 abstract 1
- 229960001171 acetohydroxamic acid Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 abstract 1
- 230000001545 erythrolytic effect Effects 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- UYDLBVPAAFVANX-UHFFFAOYSA-N octylphenoxy polyethoxyethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCOCCOCCO)C=C1 UYDLBVPAAFVANX-UHFFFAOYSA-N 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Ecology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21262694A | 1994-03-11 | 1994-03-11 | |
| PCT/US1995/002897 WO1995024651A1 (en) | 1994-03-11 | 1995-03-06 | Cyanide-free reagent and method for the determination of hemoglobin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE223059T1 true ATE223059T1 (de) | 2002-09-15 |
Family
ID=22791814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95912800T ATE223059T1 (de) | 1994-03-11 | 1995-03-06 | Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5612223A (de) |
| EP (1) | EP0749583B1 (de) |
| JP (1) | JP3523878B2 (de) |
| AT (1) | ATE223059T1 (de) |
| AU (1) | AU1984295A (de) |
| CA (1) | CA2183558C (de) |
| DE (1) | DE69527947T2 (de) |
| ES (1) | ES2184795T3 (de) |
| WO (1) | WO1995024651A1 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3094695A (en) * | 1994-07-14 | 1996-02-16 | Abbott Laboratories | Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood |
| US5834315A (en) * | 1994-12-23 | 1998-11-10 | Coulter Corporation | Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation |
| US5763280A (en) * | 1997-01-21 | 1998-06-09 | Coulter International Corp. | Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis |
| US5882934A (en) * | 1997-01-21 | 1999-03-16 | Coulter International Corp. | Composition and method for hemoglobin and cell analysis |
| US5858794A (en) * | 1997-05-13 | 1999-01-12 | Bayer Corporation | Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers |
| US5935857A (en) * | 1997-08-01 | 1999-08-10 | Coulter International Corp. | Blood diluent |
| US6074881A (en) * | 1998-08-03 | 2000-06-13 | Bayer Corporation | Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity |
| DE19835243A1 (de) * | 1998-08-04 | 2000-02-24 | Lmb Technologie Gmbh | Vorrichtung und Verfahren zum Bestimmen eines Hämoglobinwerts von Blut |
| JPWO2002021142A1 (ja) * | 2000-09-07 | 2004-01-15 | 和光純薬工業株式会社 | 総ヘモグロビン及び糖化ヘモグロビンの測定方法 |
| GB0110053D0 (en) * | 2001-04-24 | 2001-06-13 | Axis Shield Asa | Assay |
| JP2005506525A (ja) | 2001-07-27 | 2005-03-03 | ベックマン コールター，インコーポレーテッド | 有核赤血球の計測法の方法 |
| US6916658B2 (en) | 2001-07-27 | 2005-07-12 | Beckman Coulter, Inc. | Method for measurement of immature granulocytes |
| US6410330B1 (en) | 2001-07-27 | 2002-06-25 | Coulter International Corp. | Method for measurement of nucleated red blood cells |
| US6573102B2 (en) | 2001-07-27 | 2003-06-03 | Coulter International Corp. | Lytic reagent composition for determination of nucleated blood cells |
| US6890756B2 (en) * | 2002-04-05 | 2005-05-10 | Streck Laboratories, Inc. | Method of using cyanide-free lyse solution to emulate a cyanide-containing lyse solution in the measurement of hemoglobin |
| IES20020936A2 (en) * | 2002-12-03 | 2003-11-26 | Trinity Res Ltd | A cyanide-free reagent for measuring haemoglobin in blood, and a method for measuring haemoglobin |
| ATE464562T1 (de) * | 2004-10-20 | 2010-04-15 | Chempaq As | Lysereagens zur gleichzeitigen auszählung unterschiedlicher arten von blutzellen in einer blutprobe |
| US7235404B2 (en) | 2005-05-04 | 2007-06-26 | Beckman Coulter, Inc. | Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement |
| DE102005060993A1 (de) * | 2005-12-20 | 2007-06-28 | Medisynthana Diagnostics Gmbh & Co. Kg | Konversionsreagenz sowie Verfahren und Kit zur Bestimmung des Hämoglobins |
| EP1976541B1 (de) * | 2006-01-20 | 2011-07-13 | Beckman Coulter, Inc. | Prozentsatz an zellen mit niedriger hämoglobinkonzentration und verfahren für den nachweis von eisenmangel |
| GB2445441B (en) * | 2006-09-26 | 2010-06-30 | Ge Healthcare Bio Sciences | Nucleic acid purification method |
| GB2443505B (en) * | 2006-09-26 | 2008-12-31 | Ge Healthcare Bio Sciences | Nucleic acid purification method |
| GB2445442A (en) * | 2006-09-26 | 2008-07-09 | Ge Healthcare Bio Sciences | Nucleic acid purification using anion exchange |
| WO2009100172A1 (en) | 2008-02-07 | 2009-08-13 | Ge Healthcare Bio-Sciences Corp. | Isolation of dna, rna and protein from a single sample |
| CN102282467B (zh) | 2008-11-13 | 2014-08-13 | 贝克曼考尔特公司 | 对血红蛋白测量的颗粒干扰的校正的方法 |
| US8614066B2 (en) | 2009-08-26 | 2013-12-24 | Abbott Laboratories | Method of using ligand-free lysing agent in hemoglobin analysis |
| US20140152801A1 (en) | 2009-10-28 | 2014-06-05 | Alentic Microscience Inc. | Detecting and Using Light Representative of a Sample |
| US8603309B2 (en) * | 2011-09-12 | 2013-12-10 | Nova Biomedical Corporation | Disposable sensor for electrochemical detection of hemoglobin |
| US10502666B2 (en) * | 2013-02-06 | 2019-12-10 | Alentic Microscience Inc. | Sample processing improvements for quantitative microscopy |
| CA3080335C (en) | 2013-06-26 | 2023-06-13 | Alentic Microscience Inc. | Sample processing improvements for microscopy |
| CN103698501B (zh) * | 2013-12-23 | 2015-07-29 | 深圳开立生物医疗科技股份有限公司 | 一种无氰化物溶血剂 |
| GB201716136D0 (en) * | 2017-10-03 | 2017-11-15 | Cyanoguard Ag | Process |
| CN107907690B (zh) * | 2017-11-15 | 2020-07-10 | 南通伊仕生物技术股份有限公司 | 一种超敏c反应蛋白检测试剂盒及其使用方法 |
| WO2020054572A1 (ja) * | 2018-09-12 | 2020-03-19 | 積水メディカル株式会社 | ヘモグロビン類測定用試薬及びヘモグロビン類の測定方法 |
| JP2023027418A (ja) * | 2019-12-12 | 2023-03-02 | Ｐｈｃホールディングス株式会社 | 糖化ヘモグロビンの電気化学測定方法およびそれに用いる測定キット |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200435A (en) * | 1978-12-26 | 1980-04-29 | Abbott Laboratories | Determination of glycosylated hemoglobin in blood |
| US4255385A (en) * | 1979-10-23 | 1981-03-10 | Abbott Laboratories | Reagent and test kit for determining glycosylated hemoglobin |
| US4274978A (en) * | 1979-12-07 | 1981-06-23 | Abbott Laboratories | Standards for determining glycosylated hemoglobin |
| EP0184787B1 (de) * | 1984-12-06 | 1991-04-03 | TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation) | Cyanidfreies Hämoglobinreagens |
| US4853338A (en) * | 1987-05-20 | 1989-08-01 | Technicon Instruments Corporation | Cyanide-free hemoglobin reagent |
| JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
| JP2836865B2 (ja) * | 1989-10-23 | 1998-12-14 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬 |
| US5242832A (en) * | 1990-03-01 | 1993-09-07 | Toa Medical Electronics Co., Ltd. | Reagent for measurement of leukocytes and hemoglobin in blood |
| GB9024771D0 (en) * | 1990-11-14 | 1991-01-02 | Axis Research | Assay |
-
1995
- 1995-03-06 JP JP52362295A patent/JP3523878B2/ja not_active Expired - Fee Related
- 1995-03-06 EP EP95912800A patent/EP0749583B1/de not_active Expired - Lifetime
- 1995-03-06 AU AU19842/95A patent/AU1984295A/en not_active Abandoned
- 1995-03-06 DE DE69527947T patent/DE69527947T2/de not_active Expired - Lifetime
- 1995-03-06 CA CA002183558A patent/CA2183558C/en not_active Expired - Fee Related
- 1995-03-06 AT AT95912800T patent/ATE223059T1/de not_active IP Right Cessation
- 1995-03-06 WO PCT/US1995/002897 patent/WO1995024651A1/en active IP Right Grant
- 1995-03-06 ES ES95912800T patent/ES2184795T3/es not_active Expired - Lifetime
- 1995-08-31 US US08/524,128 patent/US5612223A/en not_active Expired - Lifetime
-
1996
- 1996-10-15 US US08/730,193 patent/US5866428A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995024651A1 (en) | 1995-09-14 |
| DE69527947D1 (de) | 2002-10-02 |
| AU1984295A (en) | 1995-09-25 |
| US5866428A (en) | 1999-02-02 |
| CA2183558A1 (en) | 1995-09-14 |
| JPH09511575A (ja) | 1997-11-18 |
| ES2184795T3 (es) | 2003-04-16 |
| EP0749583A1 (de) | 1996-12-27 |
| DE69527947T2 (de) | 2003-05-28 |
| EP0749583B1 (de) | 2002-08-28 |
| CA2183558C (en) | 2006-01-24 |
| US5612223A (en) | 1997-03-18 |
| JP3523878B2 (ja) | 2004-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE223059T1 (de) | Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin | |
| DE3853671D1 (de) | Reagens und Verfahren zur Messung von Leukozyten und Hämoglobin im Blut. | |
| ATE223044T1 (de) | Nachweis von retikulozyten mit coriphosphin o | |
| ATE117803T1 (de) | Reagenz und verfahren zur verwendung desselben in der automatischen durchflusszytometrischen bestimmung von mindestens einer leukocyten- subpopulation aus vollblut. | |
| DE69623174D1 (de) | Verfahren und Reagenszusammensetzung zur Durchführung von differenzierenden Leukocytzählungen in frischen und gealteren Vollblutproben, auf der Grundlage der bereitsvorhandenen Peroxidaseaktivität der Leukocyten | |
| IL103056A (en) | Method for sphering of red blood cells | |
| ATE219245T1 (de) | Biosensor, iontophoretischen probenahmesystem, und verfahren zur seiner anwendung | |
| DE69223930D1 (de) | Reagenzzusammensetzungen und ihre Verwendung bei der Identifizierung und Charakterisierung von Retikulozyten in Vollblut | |
| DE69411928D1 (de) | Verfahren, reagenz und testsatz zum nachweis von okkultem blut in stuhl | |
| EP0869347A3 (de) | Verfahren und Reagent zur Identifikation von Retikulozyten, Erythrozyten und Blutplättchen | |
| DE60034479D1 (de) | Vorrichtung und verfahren zum bestimmen der koagulation in flüssigproben | |
| DE3876761D1 (de) | Denaturierende reagenzien zur bestimmung von haemoglobinderivaten im blut. | |
| DE59007613D1 (de) | Verfahren zum Nachweis und zur Bestimmung von Humanserumalbumin in biologischen Flüssigkeiten mit Hilfe fluorogener Cyanin-Farbstoffe. | |
| CA2191614A1 (en) | Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood | |
| DE68917613D1 (de) | Natriumdecylsulfat enthaltende Waschlösung, Testsatz und Verfahren zur Bestimmung eines immunologischen Liganden. | |
| CA2149903A1 (en) | Use of capillary electrophoresis for quantitating the concentration of protein components and of the total protein in fluids | |
| ATE74211T1 (de) | Verfahren zum nachweis eines analyten sowie hierfuer geeignetes mittel. | |
| ATE84541T1 (de) | Verfahren zur renaturierung von proteinen. | |
| DE59510217D1 (de) | Verfahren zur Reduzierung der Beeinflussung von diagnostischen Tests durch Heparin unter Verwendung von Metallsalzen und diagnostisches Reagenz für diagnostische Tests zur Bestimmung der Gerinnungsfähigkeit des Blutes enthaltend Metallsalze | |
| DE3885642D1 (de) | Reagens und Verfahren zur Bestimmung von Hämoglobin im Blut. | |
| DE69124030D1 (de) | Testverfahren, die ein lösliches fibrinähnliches Monomer nutzen | |
| DE69430410D1 (de) | Methode zum Nachweis von Fructosamin | |
| DE69832090D1 (de) | Verfahren zur bestimmung der konzentration eines analyten unter verwendung eines bioelementes und einen transduzer, und eine vorrichtung mit einem kleinen volumen zur verwendung im verfahren | |
| DE69032131D1 (de) | Verfahren und vorrichtung zur bestimmung von glykosyliertem protein | |
| DE69922213D1 (de) | Verfahren und testsatz zur bestimmung der analytkonzentration im blut |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0749583 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |