ATE219358T1 - Sublinguale und bukkale verabreichung von selegilin - Google Patents
Sublinguale und bukkale verabreichung von selegilinInfo
- Publication number
- ATE219358T1 ATE219358T1 AT96938783T AT96938783T ATE219358T1 AT E219358 T1 ATE219358 T1 AT E219358T1 AT 96938783 T AT96938783 T AT 96938783T AT 96938783 T AT96938783 T AT 96938783T AT E219358 T1 ATE219358 T1 AT E219358T1
- Authority
- AT
- Austria
- Prior art keywords
- selegiline
- conditions
- diseases
- sublingual
- responsive diseases
- Prior art date
Links
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 title abstract 6
- 229960003946 selegiline Drugs 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 230000007954 hypoxia Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000003961 neuronal insult Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US732595P | 1995-11-06 | 1995-11-06 | |
| PCT/US1996/017745 WO1997017067A1 (en) | 1995-11-06 | 1996-11-05 | Sublingual and buccal administration of selegiline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219358T1 true ATE219358T1 (de) | 2002-07-15 |
Family
ID=21725510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96938783T ATE219358T1 (de) | 1995-11-06 | 1996-11-05 | Sublinguale und bukkale verabreichung von selegilin |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6117912A (de) |
| EP (1) | EP0866691B2 (de) |
| JP (1) | JPH11504944A (de) |
| CN (1) | CN1207675A (de) |
| AT (1) | ATE219358T1 (de) |
| AU (1) | AU707646B2 (de) |
| CA (1) | CA2236368C (de) |
| DE (1) | DE69621946T3 (de) |
| DK (1) | DK0866691T4 (de) |
| ES (1) | ES2180809T5 (de) |
| NO (1) | NO317855B1 (de) |
| PT (1) | PT866691E (de) |
| WO (1) | WO1997017067A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050106241A1 (en) * | 1995-02-03 | 2005-05-19 | Brewer Francesca M. | Pharmaceutical composition formulated for pre-gastric absorption of monoamine oxidase B inhibitors |
| SI0814789T2 (sl) † | 1995-03-02 | 2008-04-30 | Scherer Technologies Inc R P | Farmacevtske zmesi, ki obsegajo inhibitorje monoamin oksidaze b |
| GB9715082D0 (en) * | 1997-07-17 | 1997-09-24 | Scherer Ltd R P | Treatment of attention deficit hyperactivity disorder and narcolepsy |
| US20030091629A1 (en) * | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
| US6974590B2 (en) * | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
| US6200604B1 (en) * | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
| US20030118645A1 (en) * | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
| US6576250B1 (en) | 1998-03-27 | 2003-06-10 | Cima Labs Inc. | Pharmaceutical compositions for rectal and vaginal administration |
| US6350470B1 (en) | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
| DE19814257A1 (de) | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Brauseformulierungen |
| US7232830B2 (en) * | 1998-06-26 | 2007-06-19 | Elaine A Delack | Method for treatment of neurodegenerative diseases and effects of aging |
| AU2007203233B2 (en) * | 1999-03-26 | 2010-02-25 | Cima Labs Inc. | Sublingual buccal effervescent |
| AU2004242477B2 (en) * | 1999-03-26 | 2007-04-19 | Cima Labs Inc. | Sublingual buccal effervescent |
| GB0017952D0 (en) * | 2000-07-22 | 2000-09-13 | Univ Manchester | Treatment of dyskinesia |
| US7619005B2 (en) | 2000-11-01 | 2009-11-17 | Cognition Pharmaceuticals Llc | Methods for treating cognitive impairment in humans with Multiple Sclerosis |
| EP1743631A3 (de) * | 2000-11-01 | 2009-11-18 | Cognition Pharmaceuticals LLC | Verwendung von Amphetamin-enthaltenden Zusammensetzungen zum Regulieren der Gedächtnis-Konsolidierung |
| US20030232890A1 (en) | 2000-11-01 | 2003-12-18 | Sention, Inc. | Methods for treating an impairment in memory consolidation |
| WO2002039998A2 (en) * | 2000-11-01 | 2002-05-23 | Sention, Inc. | Methods and compositions for regulating memory consolidation |
| US20030068356A1 (en) | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
| CA2474154A1 (en) * | 2002-01-18 | 2003-07-24 | Tatton Technologies, Llc. | Methods for treating eye disorders |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
| GB0217056D0 (en) * | 2002-07-23 | 2002-08-28 | Ass Octel | Use |
| US20040067986A1 (en) * | 2002-10-04 | 2004-04-08 | Nathan Sassover | Neuro-degenerative inhibitor, neuro-endocrine modulator, and neuro-cerebral metabolism enhancer |
| CA2549642C (en) * | 2003-12-31 | 2012-10-30 | Cima Labs Inc. | Effervescent oral opiate dosage forms and methods of administering opiates |
| WO2005065319A2 (en) * | 2003-12-31 | 2005-07-21 | Cima Labs Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
| US7858121B2 (en) * | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
| WO2006091544A2 (en) * | 2005-02-22 | 2006-08-31 | Northwestern University | Methods and compositions for modulating calcium channels |
| EP1959969A2 (de) * | 2005-07-01 | 2008-08-27 | The Johns Hopkins University | Zusammensetzungen und verfahren zur behandlung oder prävention von erkrankungen im zusammenhang mit oxidativem stress |
| CN103860503A (zh) * | 2012-12-10 | 2014-06-18 | 天津市汉康医药生物技术有限公司 | 一种治疗帕金森病的缓释药物组合物及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3764144D1 (de) * | 1986-04-16 | 1990-09-13 | Asta Pharma Ag | Synergistische kombination von amantadin und selegilin. |
| EP0252290B1 (de) * | 1986-06-10 | 1992-06-03 | CHIESI FARMACEUTICI S.p.A. | Levodopa-methyl-ester enthaltende pharmazeutische Zusammensetzungen, ihre Herstellung und therapeutische Verwendungen |
| US4861800A (en) * | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| US4885154A (en) * | 1988-03-01 | 1989-12-05 | Alza Corporation | Method for reducing sensitization or irritation in transdermal drug delivery and means therefor |
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| HU208484B (en) * | 1988-08-17 | 1993-11-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia |
| US5221536A (en) * | 1990-05-07 | 1993-06-22 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| US5192550A (en) * | 1990-05-07 | 1993-03-09 | Alza Corporation | Dosage form for treating central nervous system disorders |
| US5057321A (en) * | 1990-06-13 | 1991-10-15 | Alza Corporation | Dosage form comprising drug and maltodextrin |
| CA2039194C (en) * | 1990-08-31 | 1997-01-28 | Norton W. Milgram | Uses of l-deprenyl and compositions for same |
| US5151449A (en) * | 1990-08-31 | 1992-09-29 | Deprenyl Animal Health, Inc. | Use of L-deprenyl for retention of specific physiological functions |
| US5192808A (en) * | 1990-08-31 | 1993-03-09 | Deprenyl Animal Health, Inc. | Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease) |
| US5332576A (en) * | 1991-02-27 | 1994-07-26 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5444095A (en) * | 1991-04-04 | 1995-08-22 | University Of Toronto, Innovations Foundation | Use of deprenyl to rescue damaged nerve cells |
| US5266332A (en) * | 1991-12-06 | 1993-11-30 | Alza Corporation | Method for administering anti-Parkinson drug |
| US5242950A (en) * | 1992-04-23 | 1993-09-07 | Somerset Pharmaceuticals, Inc. | Treatment of macular degeneration |
| US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
| US5354885A (en) * | 1992-12-24 | 1994-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Process for preparing ethyl ester of L-DOPA |
| SI0814789T2 (sl) * | 1995-03-02 | 2008-04-30 | Scherer Technologies Inc R P | Farmacevtske zmesi, ki obsegajo inhibitorje monoamin oksidaze b |
-
1996
- 1996-11-05 AT AT96938783T patent/ATE219358T1/de not_active IP Right Cessation
- 1996-11-05 DK DK96938783T patent/DK0866691T4/da active
- 1996-11-05 CN CN96199433A patent/CN1207675A/zh active Pending
- 1996-11-05 DE DE69621946T patent/DE69621946T3/de not_active Expired - Fee Related
- 1996-11-05 CA CA002236368A patent/CA2236368C/en not_active Expired - Fee Related
- 1996-11-05 PT PT96938783T patent/PT866691E/pt unknown
- 1996-11-05 WO PCT/US1996/017745 patent/WO1997017067A1/en not_active Ceased
- 1996-11-05 ES ES96938783T patent/ES2180809T5/es not_active Expired - Lifetime
- 1996-11-05 EP EP96938783A patent/EP0866691B2/de not_active Expired - Lifetime
- 1996-11-05 AU AU76080/96A patent/AU707646B2/en not_active Ceased
- 1996-11-05 JP JP9518280A patent/JPH11504944A/ja active Pending
-
1998
- 1998-04-28 US US09/066,916 patent/US6117912A/en not_active Expired - Fee Related
- 1998-05-05 NO NO19982044A patent/NO317855B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2236368A1 (en) | 1997-05-15 |
| NO982044D0 (no) | 1998-05-05 |
| DK0866691T3 (da) | 2002-10-14 |
| DK0866691T4 (da) | 2005-06-06 |
| CN1207675A (zh) | 1999-02-10 |
| US6117912A (en) | 2000-09-12 |
| NO982044L (no) | 1998-07-02 |
| WO1997017067A1 (en) | 1997-05-15 |
| DE69621946D1 (de) | 2002-07-25 |
| JPH11504944A (ja) | 1999-05-11 |
| NO317855B1 (no) | 2004-12-20 |
| EP0866691A1 (de) | 1998-09-30 |
| DE69621946T2 (de) | 2003-01-30 |
| ES2180809T5 (es) | 2005-06-16 |
| EP0866691B1 (de) | 2002-06-19 |
| EP0866691B2 (de) | 2005-01-26 |
| AU707646B2 (en) | 1999-07-15 |
| ES2180809T3 (es) | 2003-02-16 |
| AU7608096A (en) | 1997-05-29 |
| CA2236368C (en) | 2001-10-23 |
| DE69621946T3 (de) | 2005-05-25 |
| PT866691E (pt) | 2002-11-29 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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| REN | Ceased due to non-payment of the annual fee |