ATE218896T1 - Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen - Google Patents

Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen

Info

Publication number
ATE218896T1
ATE218896T1 AT98202360T AT98202360T ATE218896T1 AT E218896 T1 ATE218896 T1 AT E218896T1 AT 98202360 T AT98202360 T AT 98202360T AT 98202360 T AT98202360 T AT 98202360T AT E218896 T1 ATE218896 T1 AT E218896T1
Authority
AT
Austria
Prior art keywords
ester units
chain ester
copolyester
bone
thermoplastic copolyester
Prior art date
Application number
AT98202360T
Other languages
English (en)
Inventor
Bruijn Joost Dick De
Yvonne Pearl Bovell
Den Brink Jennigje Van
Blitterswijk Clemens Anton Van
Original Assignee
Isotis Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isotis Nv filed Critical Isotis Nv
Application granted granted Critical
Publication of ATE218896T1 publication Critical patent/ATE218896T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98202360T 1997-07-16 1998-07-14 Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen ATE218896T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202214 1997-07-16

Publications (1)

Publication Number Publication Date
ATE218896T1 true ATE218896T1 (de) 2002-06-15

Family

ID=8228565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98202360T ATE218896T1 (de) 1997-07-16 1998-07-14 Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen

Country Status (5)

Country Link
US (1) US6228117B1 (de)
AT (1) ATE218896T1 (de)
CA (1) CA2243248A1 (de)
DE (1) DE69805920T2 (de)
ES (1) ES2178102T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395036B1 (en) * 1998-04-06 2002-05-28 Isis Innovation Limited Composite material and methods of making the same
MXPA01005564A (es) * 1998-12-04 2003-07-14 Naval Medical Res Ct Celulas del endotelio cerebral humano en medio de crecimiento y metodo para expansion de celulas de tallo de medula osea cd34+cd38-nativas.
US6656489B1 (en) * 1999-02-10 2003-12-02 Isotis N.V. Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material
AU2002251725A1 (en) * 2001-01-02 2002-07-16 Advanced Ceramics Research, Inc. Compositions and methods for biomedical applications
US20060094112A1 (en) * 2001-03-07 2006-05-04 Omotunde Babalola Biological scaffold
US6884432B2 (en) * 2002-04-25 2005-04-26 Mayo Foundation For Medical Education And Research Blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery
US7574796B2 (en) 2002-10-28 2009-08-18 Geo2 Technologies, Inc. Nonwoven composites and related products and methods
US7572311B2 (en) 2002-10-28 2009-08-11 Geo2 Technologies, Inc. Highly porous mullite particulate filter substrate
US7582270B2 (en) 2002-10-28 2009-09-01 Geo2 Technologies, Inc. Multi-functional substantially fibrous mullite filtration substrates and devices
US6946013B2 (en) 2002-10-28 2005-09-20 Geo2 Technologies, Inc. Ceramic exhaust filter
US20060140914A1 (en) * 2002-10-31 2006-06-29 The General Hospital Corporation Repairing or replacing tissues or organs
EP1748744A4 (de) * 2004-05-11 2011-08-03 Synthasome Inc Gewebegerüst
JP2007537007A (ja) * 2004-05-12 2007-12-20 マサチューセッツ インスティテュート オブ テクノロジー 溶剤蒸気膜形成を含んだ立体印刷法等の製法
US7211232B1 (en) 2005-11-07 2007-05-01 Geo2 Technologies, Inc. Refractory exhaust filtering method and apparatus
US7682578B2 (en) 2005-11-07 2010-03-23 Geo2 Technologies, Inc. Device for catalytically reducing exhaust
US7682577B2 (en) 2005-11-07 2010-03-23 Geo2 Technologies, Inc. Catalytic exhaust device for simplified installation or replacement
US7722828B2 (en) 2005-12-30 2010-05-25 Geo2 Technologies, Inc. Catalytic fibrous exhaust system and method for catalyzing an exhaust gas
US7444805B2 (en) 2005-12-30 2008-11-04 Geo2 Technologies, Inc. Substantially fibrous refractory device for cleaning a fluid
US7563415B2 (en) 2006-03-03 2009-07-21 Geo2 Technologies, Inc Catalytic exhaust filter device
US20090259263A1 (en) * 2008-04-11 2009-10-15 Biomet Microfixation, Inc. Apparatus and methods of fixating bone
EP2625264B1 (de) 2010-10-08 2022-12-07 Terumo BCT, Inc. Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
CN103224629B (zh) * 2013-05-15 2014-06-18 福州赛孚玛尼环保科技有限公司 一种净化用甘蔗渣的化学改性方法
EP3068866B1 (de) 2013-11-16 2018-04-25 Terumo BCT, Inc. Zellenexpansion in einem bioreaktor
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
DE102014008476A1 (de) 2014-06-05 2015-12-17 Michael Jagodzinski Herstellung einer Komponente zur Züchtung eines Gelenkflächenimplantats, Züchtung und Implantation eines Gelenkflächenimplantats
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266480A (en) 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5041138A (en) 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
NL8802178A (nl) 1988-09-02 1990-04-02 Stichting Tech Wetenschapp Prothetische voortbrengsels met botbindende eigenschappen.
US5226914A (en) 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
JPH05103827A (ja) 1991-10-15 1993-04-27 Nippon Sherwood Kk 生体活性アパタイト膜をコーテイングした生体インプラント部材
WO1993021858A1 (en) 1992-04-24 1993-11-11 Osteotech, Inc. Devices for preventing tissue adhesion
US5399665A (en) 1992-11-05 1995-03-21 Massachusetts Institute Of Technology Biodegradable polymers for cell transplantation
US5522895A (en) 1993-07-23 1996-06-04 Rice University Biodegradable bone templates
US5569250A (en) * 1994-03-01 1996-10-29 Sarver; David R. Method and apparatus for securing adjacent bone portions
US5629186A (en) * 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US5972703A (en) 1994-08-12 1999-10-26 The Regents Of The University Of Michigan Bone precursor cells: compositions and methods
DE4435680A1 (de) 1994-10-06 1996-04-11 Merck Patent Gmbh Poröse Knochenersatzmaterialien
US5688531A (en) 1994-12-23 1997-11-18 Ramot University Authority For Applied Research And Industrial Development, Ltd. Method for regulating bone forming cells
US5489306A (en) 1995-01-03 1996-02-06 Gorski; Jerrold M. Graduated porosity implant for fibro-osseous integration
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
DE69634303T2 (de) 1995-11-16 2006-01-05 Case Western Reserve University, Cleveland Chondrogene in vitro induktion von menschlichen mensenchymalen stammzellen

Also Published As

Publication number Publication date
DE69805920D1 (de) 2002-07-18
DE69805920T2 (de) 2003-01-02
CA2243248A1 (en) 1999-01-16
US6228117B1 (en) 2001-05-08
ES2178102T3 (es) 2002-12-16

Similar Documents

Publication Publication Date Title
ATE218896T1 (de) Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen
Kint et al. A review on the potential biodegradability of poly (ethylene terephthalate)
NO994802D0 (no) Bionedbrytbare tereftalatpolyester-poly(fosfat)-polymerer, blandinger, gjenstander og fremgangsmÕte for fremstilling og anvendelse derav
EP0736557B1 (de) Aliphatisch-aromatische Copolyester
DE60019354T2 (de) Verfahren zur Knorpelgeweberegeneration
EP0295055A3 (de) Biodegradierbare polymere Materialien auf der Basis von Polyetherglycolen, Verfahren zu ihrer Herstellung und chirurgische Gegenstände daraus
EP1027897B1 (de) Verfahren zur Knorpelgeweberegeneration
CA2369758A1 (en) Functionalized poly(propylene fumarate) and poly(propylene fumarate-co-ethylene glycol)
WO1998051812A3 (en) Polyhydroxyalkanoates for in vivo applications
Feng et al. Progress in depsipeptide‐based biomaterials
DE69731205D1 (de) Verbessertes verfahren zur herstellung hochmolekularer polyester
ATE282653T1 (de) Saure polymilchsäure polymere
PL327246A1 (en) Linear block polymer containing urea and urethane groups, method of obtaining them and their appliocation as an implantable material
CA2180221A1 (en) Soil release polymers and detergent compositions containing them
BR9811000A (pt) "composições poliméricas"
PT863776E (pt) Material biologico compreendendo uma cultura eficiente de celulas estaminais de medula ossea parcialmente ou completamente diferenciadas em celulas detecido conjuntivo e uma matriz tridimensional biocompativel e biodegradavel consistindo num derivado de acido hialuronico
KR0137652B1 (en) Artificial skin
DE3063281D1 (en) Thermoplastic, segmented copolyetherester elastomers and their use as adhesives
ATE290564T1 (de) Funktionsfähige poly-alpha-aminosäurederivate zur modifizierung von biologisch wirksamen stoffen und deren herstellung
Edlund et al. Degradable aliphatic polyesters
ES2056195T3 (es) Dispositivo protesico que tiene propiedades de union con los huesos.
AU6372399A (en) Preparation of a copolyether ester
WO2000019976A3 (en) Biodegradable terephthalate polyester-poly(phosphonate) and polyester-poly(phosphite) compositions, articles, and methods of using them
KR920000831A (ko) 지환족 하드 세그멘트를 지닌 코폴리에테르에스테르 탄성체
Mochizuki et al. Biodegradable fibers made from truly-biodegradable thermoplastics

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties