ATE213000T1 - Nichtabsorbierbare, synthetische, sulfatierte polysaccharide - Google Patents

Nichtabsorbierbare, synthetische, sulfatierte polysaccharide

Info

Publication number
ATE213000T1
ATE213000T1 AT95307295T AT95307295T ATE213000T1 AT E213000 T1 ATE213000 T1 AT E213000T1 AT 95307295 T AT95307295 T AT 95307295T AT 95307295 T AT95307295 T AT 95307295T AT E213000 T1 ATE213000 T1 AT E213000T1
Authority
AT
Austria
Prior art keywords
absorbable synthetic
sulphated polysaccharides
synthetic sulphated
polysaccharides
absorbable
Prior art date
Application number
AT95307295T
Other languages
English (en)
Inventor
Louis G Lange Iii
Curtis A Spilburg
Dayton T Reardan
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/322,782 external-priority patent/US5521303A/en
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Application granted granted Critical
Publication of ATE213000T1 publication Critical patent/ATE213000T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT95307295T 1994-10-13 1995-10-13 Nichtabsorbierbare, synthetische, sulfatierte polysaccharide ATE213000T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/322,782 US5521303A (en) 1994-10-13 1994-10-13 Method of manufacturing non-absorbable synthetic sulfated polysaccharides
US45156395A 1995-05-26 1995-05-26

Publications (1)

Publication Number Publication Date
ATE213000T1 true ATE213000T1 (de) 2002-02-15

Family

ID=26983602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95307295T ATE213000T1 (de) 1994-10-13 1995-10-13 Nichtabsorbierbare, synthetische, sulfatierte polysaccharide

Country Status (7)

Country Link
US (1) US6632801B1 (de)
EP (1) EP0712864B1 (de)
JP (1) JP2655592B2 (de)
AT (1) ATE213000T1 (de)
AU (1) AU682792B2 (de)
CA (1) CA2160440C (de)
DE (1) DE69525306T2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071174B1 (en) * 1994-10-13 2006-07-04 Cv Therapeutics, Inc. Method and composition for inhibiting cholesterol esterase
US6933372B2 (en) 2003-03-07 2005-08-23 Warner-Lambert Company Method to produce a solid form of heparin
JP5332090B2 (ja) * 2005-09-01 2013-11-06 Ｊｎｃ株式会社 球状硫酸化セルロース及びその製造方法
JP5076104B2 (ja) * 2007-03-30 2012-11-21 国立大学法人広島大学 アレルギー体質改善剤

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755275A (en) 1952-08-29 1956-07-17 Abbott Lab Process for sulfating chitin
GB871590A (en) 1958-08-18 1961-06-28 Riker Laboratories Inc Water soluble antilipemic salts of sulphated polysaccharides
GB953626A (en) 1961-04-25 1964-03-25 Meito Sangyo Kk Enteric-coated tablets of dextran sulphate ester and method of preparation thereof
US3175942A (en) 1962-03-13 1965-03-30 Evans Medical Ltd Gastro-intestinal therapeutic
GB1053143A (de) 1963-03-29 1900-01-01
US3624069A (en) 1965-06-28 1971-11-30 Kelco Co Process of preparing a gellable colloidal cellulose sulfate and product
US3511910A (en) 1966-04-08 1970-05-12 Frank E Halleck Animal food products for reducing plasma cholesterol levels
US3507855A (en) 1966-08-30 1970-04-21 Purdue Research Foundation Process of preparing cellulose sulfate and starch sulfate
ES343957A1 (es) * 1967-08-09 1968-10-01 Rocador Sa Procedimiento de obtencion de polisacaridos sulfatados an- tilipemicos activos por via oral.
US3627872A (en) 1968-04-08 1971-12-14 Upjohn Co Oral treatment of hyper-cholesteremia in mammals and birds with ether-type anion exchangers of polysaccharides
US3639665A (en) 1969-04-10 1972-02-01 Kelco Co Process of preparing a gellable collodial cellulose sulfate
FR2192813B1 (de) 1972-07-20 1975-08-08 Centre Etd Ind Pharma
JPS5027884A (de) 1973-07-12 1975-03-22
US3956173A (en) 1974-07-05 1976-05-11 Hercules Incorporated Preparation of gels based on carrageenan
US4066829A (en) 1976-07-12 1978-01-03 American Cyanamid Company Malto-dextrin poly(H-)sulfates
JPS5515435A (en) 1978-07-20 1980-02-02 Seikagaku Kogyo Co Ltd Blood platelet coagulation suppressing agent
US4223023A (en) 1978-10-12 1980-09-16 Ivan Furda Nonabsorbable lipid binder
JPS5790002A (en) 1980-11-27 1982-06-04 Asahi Chem Ind Co Ltd Cellulose sulfate containing heparin-like property and its production
IT1144697B (it) 1981-04-06 1986-10-29 Texcontor Ets Derivato semi-sintetico della chitina processo per la sua preparazione e composizioni terapeutiche che lo comprendono come principio attivo
JPS58148882A (ja) * 1982-02-26 1983-09-05 Tanabe Seiyaku Co Ltd フリルオキサゾリル酢酸誘導体及びその製法
FR2538404B1 (de) 1982-12-28 1985-08-23 Anic Spa
JPS59138202A (ja) 1983-01-27 1984-08-08 Rikagaku Kenkyusho 新規な硫酸化アミノ糖含有多糖及びその製造法
US4623539A (en) 1983-02-04 1986-11-18 Tunc Deger C Nutrient barrier polysaccharide compositions and method of use
US4480091A (en) 1983-10-31 1984-10-30 Eastman Kodak Company Process for preparing cellulose sulfate esters
SE453394B (sv) 1986-07-07 1988-02-01 Pharmacia Ab Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen
JPS6464722A (en) 1987-09-02 1989-03-10 Amada Co Ltd Control device for automatic machining of wire-cut electric discharge machine
AU3434889A (en) 1988-03-15 1989-10-05 Jewish Hospital Of St. Louis, The Inhibition of intestinal cholesterol and fatty acid absorption
US5017565A (en) 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5063210A (en) 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
US5173408A (en) 1989-11-13 1992-12-22 Lange Louis George Iii Mammalian pancreatic cholesterol esterase
US5432058A (en) 1992-09-30 1995-07-11 Lange, Iii; Louis G. Method for measuring human cholesterol absorption using metabolically stable isotopes

Also Published As

Publication number Publication date
DE69525306T2 (de) 2002-12-19
JP2655592B2 (ja) 1997-09-24
CA2160440A1 (en) 1996-04-14
AU682792B2 (en) 1997-10-16
EP0712864B1 (de) 2002-02-06
EP0712864A2 (de) 1996-05-22
US6632801B1 (en) 2003-10-14
DE69525306D1 (de) 2002-03-21
CA2160440C (en) 1998-08-25
EP0712864A3 (de) 1996-10-16
JPH08253502A (ja) 1996-10-01
AU3424095A (en) 1996-04-26

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties