ATE209345T1 - Vorrichtung und verfahren zur molekularen charakterisierung - Google Patents
Vorrichtung und verfahren zur molekularen charakterisierungInfo
- Publication number
- ATE209345T1 ATE209345T1 AT93905926T AT93905926T ATE209345T1 AT E209345 T1 ATE209345 T1 AT E209345T1 AT 93905926 T AT93905926 T AT 93905926T AT 93905926 T AT93905926 T AT 93905926T AT E209345 T1 ATE209345 T1 AT E209345T1
- Authority
- AT
- Austria
- Prior art keywords
- light
- scattered
- sample
- molecular characterization
- cell
- Prior art date
Links
- 238000012512 characterization method Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title 1
- 238000005259 measurement Methods 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0389—Windows
- G01N2021/0392—Nonplanar windows
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4711—Multiangle measurement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4728—Optical definition of scattering volume
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/064—Stray light conditioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/064—Stray light conditioning
- G01N2201/0642—Light traps; baffles
Landscapes
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Optical Measuring Cells (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/834,415 US5305073A (en) | 1992-02-12 | 1992-02-12 | Methods and apparatus for molecular characterization |
| PCT/US1993/001300 WO1993016372A1 (en) | 1992-02-12 | 1993-02-12 | Methods and apparatus for molecular characterization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE209345T1 true ATE209345T1 (de) | 2001-12-15 |
Family
ID=25266887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93905926T ATE209345T1 (de) | 1992-02-12 | 1993-02-12 | Vorrichtung und verfahren zur molekularen charakterisierung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5305073A (de) |
| EP (1) | EP0626064B1 (de) |
| JP (1) | JP3352092B2 (de) |
| AT (1) | ATE209345T1 (de) |
| CA (1) | CA2117475A1 (de) |
| DE (1) | DE69331188T2 (de) |
| WO (1) | WO1993016372A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6072187A (en) * | 1994-07-06 | 2000-06-06 | Fisher Pierce Co. | Apparatus and method for reducing stray laser light in particle sensors using a narrow band filter |
| US5701176A (en) * | 1995-07-28 | 1997-12-23 | Precision Detectors, Inc. | High temperature light scattering measurement device comprising a rigid extension tube |
| US6586193B2 (en) | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
| IL126544A (en) | 1996-04-25 | 2004-08-31 | Genicon Sciences Inc | Analyte assay using scattered-light detectable particles |
| US6653150B1 (en) | 1996-11-13 | 2003-11-25 | The Administrators Of The Tulane Educational Fund | Automatic mixing and dilution methods for online characterization of equilibrium and non-equilibrium properties of solutions containing polymers and/or colloids |
| US6052184A (en) * | 1996-11-13 | 2000-04-18 | The Administrators Of The Tulane Educational Fund | Miniature, submersible, versatile, light scattering probe for absolute equilibrium and non-equilibrium characterization of macromolecular and colloidal solutions |
| US5952896A (en) * | 1997-01-13 | 1999-09-14 | Applied Materials, Inc. | Impedance matching network |
| US6175409B1 (en) | 1999-04-02 | 2001-01-16 | Symyx Technologies, Inc. | Flow-injection analysis and variable-flow light-scattering methods and apparatus for characterizing polymers |
| US6795183B2 (en) | 1999-02-19 | 2004-09-21 | Metron Instruments, Inc. | Measurement systems and methods for determining component particle concentrations in a liquid |
| US6407813B1 (en) | 1999-02-19 | 2002-06-18 | On-Line Instrumentation, Inc. | Measurement systems and methods for determining component particle concentrations in a liquid |
| ATE417262T1 (de) * | 1999-02-19 | 2008-12-15 | Metron Instr Inc | Messvorrichtung und verfahren zur bestimmung von teilchenkonzentrationen in einer flüssigkeit |
| WO2002077671A2 (en) * | 2000-10-19 | 2002-10-03 | Viscotek Corporation | Miniature low angle laser light scattering detector |
| CA2439307A1 (en) * | 2001-02-23 | 2002-09-06 | Genicon Sciences Corporation | Methods for providing extended dynamic range in analyte assays |
| GB2390893A (en) * | 2002-07-15 | 2004-01-21 | Pcme Ltd | Method and apparatus for monitoring particles in a stack |
| DE10341520A1 (de) * | 2003-09-09 | 2005-04-07 | Schupp, Wolfgang, Dr. | Verfahren und Vorrichtung zur Durchführung einer Lichtstreuung |
| US20050141843A1 (en) * | 2003-12-31 | 2005-06-30 | Invitrogen Corporation | Waveguide comprising scattered light detectable particles |
| US7027138B2 (en) * | 2004-01-29 | 2006-04-11 | Wyatt Technology Corporation | Enhanced sensitivity differential refractometer incorporating a photodetector array |
| WO2006029017A1 (en) * | 2004-09-03 | 2006-03-16 | Symyx Technologies, Inc. | System and method for rapid chromatography with fluid temperature and mobile phase composition control |
| GB2422897A (en) | 2005-02-02 | 2006-08-09 | Pcme Ltd | A monitor for monitoring particles flowing in a stack |
| US7630076B2 (en) * | 2005-07-26 | 2009-12-08 | University Of Connecticut | Dual-detector systems and methods having utility in biomolecular measurements |
| GB2436871A (en) * | 2006-04-04 | 2007-10-10 | Pcme Ltd | Optical beam dump for particle monitoring system |
| US20090046274A1 (en) * | 2007-08-16 | 2009-02-19 | Mchugh Mark A | Light Scattering Methods and Systems Using Supercritical Fluid Solvents to Measure Polymer Molecular Weight and Molecular Weight Distribution |
| KR101109968B1 (ko) * | 2008-07-23 | 2012-02-17 | 올림푸스 메디칼 시스템즈 가부시키가이샤 | 피검체 관측 장치 및 피검체 관측 방법 |
| JP5191831B2 (ja) * | 2008-07-23 | 2013-05-08 | オリンパスメディカルシステムズ株式会社 | 被検体観測装置及び被検体観測装置の作動方法 |
| US8576396B2 (en) * | 2008-11-19 | 2013-11-05 | Postnova Analytics Gmbh | Cell construction for light scatter detectors having self-focusing properties |
| US7659980B1 (en) * | 2008-11-24 | 2010-02-09 | Herbert Leckie Mitchell | Nephelometric turbidity sensor device |
| US8531516B2 (en) * | 2010-02-03 | 2013-09-10 | The United States Of America As Represented By The Secretary Of Commerce | Imaging polar nephelometer |
| GB201003704D0 (en) * | 2010-03-05 | 2010-04-21 | Pcme Ltd | Apparatus and method for monitoring particles in a stack |
| US20120001061A1 (en) * | 2010-07-02 | 2012-01-05 | Hamilton Sundstrand Corporation | Ion implanted beam dump |
| AT510765B1 (de) * | 2010-12-15 | 2012-09-15 | Wolfgang Dipl Ing Vogl | Vorrichtung zur photometrischen bzw. spektrometrischen untersuchung einer flüssigen probe |
| DE202011107342U1 (de) | 2011-10-18 | 2012-07-18 | Postnova Analytics Gmbh | Blendensystem für Vielwinkellichtstreudetektoren |
| EP2584353B1 (de) | 2011-10-18 | 2018-01-24 | Postnova Analytics GmbH | Blendensystem für Vielwinkellichtstreudetektoren |
| EP3066452B1 (de) * | 2013-11-05 | 2018-04-04 | Malvern Panalytical Limited | Verbesserungen in zusammenhang mit partikelcharakterisierung |
| DE202014102634U1 (de) | 2014-06-05 | 2014-07-01 | Postnova Analytics Gmbh | Zweiteilige Messzelle für die statische Lichtstreuung |
| US9677983B2 (en) * | 2015-05-01 | 2017-06-13 | Malvern Instruments Ltd. | Particle characterization |
| DE202019104338U1 (de) | 2018-08-09 | 2019-09-04 | Postnova Analytics Gmbh | Vielwinkellichtstreudetektor auf Basis eines Fotodiodenarray |
| JP7192675B2 (ja) * | 2019-06-26 | 2022-12-20 | 株式会社島津製作所 | 光散乱検出装置および光散乱検出方法 |
| JP7226561B2 (ja) * | 2019-08-05 | 2023-02-21 | 株式会社島津製作所 | 液体クロマトグラフ用検出器 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2427996A (en) * | 1944-09-28 | 1947-09-23 | American Cyanamid Co | Temperature compensator for refractometers |
| US4027973A (en) * | 1973-07-02 | 1977-06-07 | Beckman Instruments, Inc. | Detector apparatus for laser light scattering photometers |
| US4053229A (en) * | 1976-01-13 | 1977-10-11 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | 2°/90° Laboratory scattering photometer |
| CH668483A5 (de) * | 1985-12-17 | 1988-12-30 | Zellweger Uster Ag | Verfahren und vorrichtung zur bestimmung der oberflaechenstruktur eines langgestreckten pruefkoerpers, insbesondere zur messung der haarigkeit eines garnes. |
| US4804853A (en) * | 1987-04-23 | 1989-02-14 | High Yield Technology | Compact particle flux monitor |
| JP2635992B2 (ja) * | 1988-03-24 | 1997-07-30 | 興和株式会社 | 微粒子測定装置 |
-
1992
- 1992-02-12 US US07/834,415 patent/US5305073A/en not_active Expired - Lifetime
-
1993
- 1993-02-12 WO PCT/US1993/001300 patent/WO1993016372A1/en not_active Ceased
- 1993-02-12 AT AT93905926T patent/ATE209345T1/de not_active IP Right Cessation
- 1993-02-12 JP JP51431193A patent/JP3352092B2/ja not_active Expired - Lifetime
- 1993-02-12 DE DE69331188T patent/DE69331188T2/de not_active Expired - Lifetime
- 1993-02-12 EP EP93905926A patent/EP0626064B1/de not_active Expired - Lifetime
- 1993-02-12 CA CA002117475A patent/CA2117475A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07503796A (ja) | 1995-04-20 |
| EP0626064B1 (de) | 2001-11-21 |
| US5305073A (en) | 1994-04-19 |
| DE69331188T2 (de) | 2002-08-29 |
| DE69331188D1 (de) | 2002-01-03 |
| EP0626064A1 (de) | 1994-11-30 |
| EP0626064A4 (de) | 1995-05-10 |
| JP3352092B2 (ja) | 2002-12-03 |
| WO1993016372A1 (en) | 1993-08-19 |
| CA2117475A1 (en) | 1993-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |