ATE20741T1 - Verfahren zur herstellung von cytosin. - Google Patents
Verfahren zur herstellung von cytosin.Info
- Publication number
- ATE20741T1 ATE20741T1 AT82110854T AT82110854T ATE20741T1 AT E20741 T1 ATE20741 T1 AT E20741T1 AT 82110854 T AT82110854 T AT 82110854T AT 82110854 T AT82110854 T AT 82110854T AT E20741 T1 ATE20741 T1 AT E20741T1
- Authority
- AT
- Austria
- Prior art keywords
- cytosine
- isocyclic
- cyc
- chained
- atoms
- Prior art date
Links
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title abstract 6
- 229940104302 cytosine Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 150000004679 hydroxides Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813150929 DE3150929A1 (de) | 1981-12-23 | 1981-12-23 | "verfahren zur herstellung von cytosin" |
| EP82110854A EP0082339B1 (de) | 1981-12-23 | 1982-11-24 | Verfahren zur Herstellung von Cytosin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE20741T1 true ATE20741T1 (de) | 1986-08-15 |
Family
ID=6149459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82110854T ATE20741T1 (de) | 1981-12-23 | 1982-11-24 | Verfahren zur herstellung von cytosin. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0082339B1 (en, 2012) |
| JP (1) | JPS58116473A (en, 2012) |
| AT (1) | ATE20741T1 (en, 2012) |
| DE (2) | DE3150929A1 (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3434142A1 (de) * | 1984-09-18 | 1986-03-27 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur herstellung von cytosin |
| DE3829100A1 (de) * | 1988-08-27 | 1990-03-08 | Boehringer Ingelheim Kg | Verbessertes verfahren zum faellen von cytosin aus alkalischen loesungen mit schwefelsaeure |
| CN111646947A (zh) * | 2020-07-14 | 2020-09-11 | 新乡瑞诺药业有限公司 | 胞嘧啶环合过程中金属钠代替甲醇钠的制备工艺 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2892840A (en) * | 1955-12-05 | 1959-06-30 | Kay Fries Chemicals Inc | Preparation of cytosine and intermediates |
| JPS4833391A (en, 2012) * | 1971-09-02 | 1973-05-09 | ||
| JPS5384982A (en) * | 1976-12-24 | 1978-07-26 | Ajinomoto Co Inc | Process for hydrolysis of pyrimidine nucleocide and pyrimidine nucleotide |
-
1981
- 1981-12-23 DE DE19813150929 patent/DE3150929A1/de not_active Withdrawn
-
1982
- 1982-11-24 EP EP82110854A patent/EP0082339B1/de not_active Expired
- 1982-11-24 AT AT82110854T patent/ATE20741T1/de not_active IP Right Cessation
- 1982-11-24 DE DE8282110854T patent/DE3272043D1/de not_active Expired
- 1982-12-23 JP JP57225122A patent/JPS58116473A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3150929A1 (de) | 1983-06-30 |
| EP0082339A3 (en) | 1983-08-03 |
| JPS58116473A (ja) | 1983-07-11 |
| JPH0551584B2 (en, 2012) | 1993-08-03 |
| EP0082339A2 (de) | 1983-06-29 |
| DE3272043D1 (en) | 1986-08-21 |
| EP0082339B1 (de) | 1986-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |