ATE203402T1 - Verwendung von n-(2,6-dimethylphenyl)-2-(2-oxo-1- pyrrolidinyl)acetamid zur behandlung von demenz - Google Patents

Verwendung von n-(2,6-dimethylphenyl)-2-(2-oxo-1- pyrrolidinyl)acetamid zur behandlung von demenz

Info

Publication number
ATE203402T1
ATE203402T1 AT92107421T AT92107421T ATE203402T1 AT E203402 T1 ATE203402 T1 AT E203402T1 AT 92107421 T AT92107421 T AT 92107421T AT 92107421 T AT92107421 T AT 92107421T AT E203402 T1 ATE203402 T1 AT E203402T1
Authority
AT
Austria
Prior art keywords
dementia
dimethylphenyl
pyrrolidinyl
acetamide
oxo
Prior art date
Application number
AT92107421T
Other languages
English (en)
Inventor
Eiichi Otomo
Yoshiyuki Takasu
Tadashi Shiotani
Kazuo Hasegawa
Akira Honma
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE203402T1 publication Critical patent/ATE203402T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT92107421T 1991-05-02 1992-04-30 Verwendung von n-(2,6-dimethylphenyl)-2-(2-oxo-1- pyrrolidinyl)acetamid zur behandlung von demenz ATE203402T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22981991 1991-05-02
JP22981891 1991-05-02

Publications (1)

Publication Number Publication Date
ATE203402T1 true ATE203402T1 (de) 2001-08-15

Family

ID=26529012

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92107421T ATE203402T1 (de) 1991-05-02 1992-04-30 Verwendung von n-(2,6-dimethylphenyl)-2-(2-oxo-1- pyrrolidinyl)acetamid zur behandlung von demenz

Country Status (22)

Country Link
US (1) US5886023A (de)
EP (1) EP0515866B1 (de)
KR (1) KR100310590B1 (de)
AT (1) ATE203402T1 (de)
AU (2) AU1595492A (de)
CA (1) CA2067614C (de)
CZ (1) CZ281170B6 (de)
DE (1) DE69231955T2 (de)
DK (1) DK0515866T3 (de)
ES (1) ES2160097T3 (de)
GR (1) GR3036970T3 (de)
HK (1) HK1002153A1 (de)
HU (1) HU224689B1 (de)
IE (1) IE921377A1 (de)
IL (1) IL101738A (de)
MX (1) MX9202058A (de)
NO (1) NO312813B1 (de)
PT (1) PT515866E (de)
RU (1) RU2070042C1 (de)
SG (1) SG49650A1 (de)
SK (1) SK279285B6 (de)
TW (1) TW199096B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000048847A (ko) 1996-10-01 2000-07-25 스즈키 다다시 미토콘드리아 막 안정화제
DE69823851D1 (de) 1997-07-15 2004-06-17 Daiichi Seiyaku Co Nefiracetam zur prophylaxe und behandlung von propofol verursachtem gedächtnisschwund
US20040077709A1 (en) * 1999-05-31 2004-04-22 Daiichi Pharmaceutical Co., Ltd. Neuronal death inhibitors
WO2000072844A1 (fr) * 1999-05-31 2000-12-07 Daiichi Pharmaceutical Co., Ltd. Inhibiteurs de la mort neuronale
US6376489B1 (en) * 1999-12-23 2002-04-23 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
US6423739B1 (en) 2000-02-23 2002-07-23 Daiichi Pharmaceutical Co., Ltd. Method for aiding cerebral recovery following neurodegeneration
US6348489B1 (en) * 2000-04-11 2002-02-19 Daiichi Pharmaceutical Co., Ltd. Method of treating traumatic brain injury and other neuronal disorders
KR100823668B1 (ko) * 2000-12-28 2008-04-21 해밀턴 파마슈티컬스 인코포레이티드 신경성 통증 치료 및 예방약
ATE404192T1 (de) * 2001-08-22 2008-08-15 Hamilton Pharmaceuticals Inc Verwendung von nefiracetam zur behandlung von postischemischer neurodegeneration
US20060241144A1 (en) * 2005-04-20 2006-10-26 Albert Cha Method for treating apathy syndrome
US7972633B2 (en) * 2007-02-07 2011-07-05 Applied Cognitive Sciences, LLC Nutritional supplements for healthy memory and mental function
EP2346500B1 (de) * 2008-10-16 2017-05-17 The Johns Hopkins University Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion
WO2011100373A1 (en) * 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP3827820A1 (de) 2013-03-15 2021-06-02 The Johns Hopkins University Brivaracetam zur verbesserung der kognitiven funktion
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ, インコーポレイテッド 認知機能を改善するための方法および組成物
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE864269A (fr) * 1977-03-03 1978-06-16 Parke Davis & Co Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire
IT1141287B (it) * 1979-06-13 1986-10-01 Nattermann A & Cie Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono
US4385053A (en) * 1981-03-11 1983-05-24 Barry Reisberg Treatment for human memory impairment associated with aging
JPH0699307B2 (ja) * 1987-08-20 1994-12-07 キッセイ薬品工業株式会社 抗痴呆剤
IT1231477B (it) * 1989-07-12 1991-12-07 Sigma Tau Ind Farmaceuti (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti

Also Published As

Publication number Publication date
DE69231955D1 (de) 2001-08-30
GR3036970T3 (en) 2002-01-31
RU2070042C1 (ru) 1996-12-10
HUT62790A (en) 1993-06-28
SK279285B6 (sk) 1998-09-09
HK1002153A1 (en) 1998-07-31
NO921724D0 (no) 1992-04-30
CZ281170B6 (cs) 1996-07-17
ES2160097T3 (es) 2001-11-01
EP0515866A1 (de) 1992-12-02
DE69231955T2 (de) 2002-04-04
CS130692A3 (en) 1992-11-18
US5886023A (en) 1999-03-23
MX9202058A (es) 1993-03-01
NO312813B1 (no) 2002-07-08
AU1595492A (en) 1992-11-05
HU9201477D0 (en) 1992-07-28
KR920021143A (ko) 1992-12-18
PT515866E (pt) 2001-11-30
AU697936B2 (en) 1998-10-22
IE921377A1 (en) 1992-11-04
CA2067614A1 (en) 1992-11-03
DK0515866T3 (da) 2001-09-24
TW199096B (de) 1993-02-01
AU3774595A (en) 1996-03-07
KR100310590B1 (ko) 2001-12-28
IL101738A (en) 1999-01-26
EP0515866B1 (de) 2001-07-25
NO921724L (no) 1992-11-03
HU224689B1 (hu) 2005-12-28
CA2067614C (en) 2002-07-30
IL101738A0 (en) 1992-12-30
SG49650A1 (en) 1998-06-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee