ATE199498T1 - Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen - Google Patents

Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen

Info

Publication number
ATE199498T1
ATE199498T1 AT93901068T AT93901068T ATE199498T1 AT E199498 T1 ATE199498 T1 AT E199498T1 AT 93901068 T AT93901068 T AT 93901068T AT 93901068 T AT93901068 T AT 93901068T AT E199498 T1 ATE199498 T1 AT E199498T1
Authority
AT
Austria
Prior art keywords
sarcomas
pct
lif
inhibiting factor
treat tumors
Prior art date
Application number
AT93901068T
Other languages
English (en)
Inventor
George Kannourakis
Original Assignee
Amrad Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amrad Corp Ltd filed Critical Amrad Corp Ltd
Application granted granted Critical
Publication of ATE199498T1 publication Critical patent/ATE199498T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2006—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93901068T 1991-12-24 1992-12-24 Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen ATE199498T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPL016491 1991-12-24
PCT/AU1992/000683 WO1993012806A1 (en) 1991-12-24 1992-12-24 A method for the treatment of tumours and sarcomas

Publications (1)

Publication Number Publication Date
ATE199498T1 true ATE199498T1 (de) 2001-03-15

Family

ID=3775908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93901068T ATE199498T1 (de) 1991-12-24 1992-12-24 Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen

Country Status (9)

Country Link
US (1) US5599789A (de)
EP (1) EP0620736B1 (de)
JP (1) JPH07502514A (de)
KR (1) KR940702380A (de)
AT (1) ATE199498T1 (de)
AU (1) AU3251693A (de)
CA (1) CA2104576C (de)
DE (1) DE69231726D1 (de)
WO (1) WO1993012806A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021272A1 (en) * 1993-03-17 1994-09-29 Amrad Corporation Limited A method for treating microbial infection in an animal by administering a composition comprising lif and a cytokine
EP0871472A4 (de) * 1995-10-27 2001-05-30 Amrad Operations Pty Ltd Cytokine und ihre verwendung in behandlung und/oder vorbeugung von brustkrebs
AU723610B2 (en) * 1995-10-27 2000-08-31 Walter And Eliza Hall Institute Of Medical Research, The Cytokines and their use in treatment and/or prophylaxis of breast cancer
CA2615491C (en) * 2005-07-19 2016-11-29 Stemgen S.P.A. Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4840815A (de) * 1971-09-25 1973-06-15
JPS62112769A (ja) * 1985-11-12 1987-05-23 Tadahiro Shimazu 耐摩耗性、耐食性、耐久性に優れる容射被膜の形成方法
AU609128B2 (en) * 1987-04-02 1991-04-26 Amrad Operations Pty. Limited Leukaemia-inhibitory factor
PT87133B (pt) * 1987-04-02 1992-07-31 Amrad Corp Ltd Metodo de purificacao do factor inibidor da leucemia (lif) e de composicoes farmaceuticas contendo polipeptidos com actividade do lif
DE3822997A1 (de) * 1988-07-07 1990-01-18 Henkel Kgaa Detergensmischung aus nichtionischen und anionischen tensiden und deren verwendung
CA1340748C (en) * 1988-07-13 1999-09-14 Stephen Oroszlan Synthetic hiv protease gene and method for its expression
AU622515B2 (en) * 1989-01-10 1992-04-09 Amrad Operations Pty. Limited Leukaemia inhibitory factor from livestock species and use thereof to enhance implantation and development of embryonic cells
AU623987B2 (en) * 1989-03-07 1992-05-28 Amrad Operations Pty. Limited Metabolic effects of leukaemia inhibitory factor on bone
AU5958090A (en) * 1989-06-29 1991-01-17 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Method for protecting bone marrow against chemotherapeutic drugs and radiation therapy using transforming growth factor beta 1
DE69027123T2 (de) * 1989-11-24 1997-04-24 Univ Monash Proliferative wirkung des leukämie-hemmungsfaktors auf satellitzellen
GB9004890D0 (en) * 1990-03-05 1990-05-02 Heath John K Leukaemia inhibitory factor
AU635412B2 (en) * 1990-03-20 1993-03-18 Amrad Operations Pty. Limited A method for regulating neuron development and maintenance

Also Published As

Publication number Publication date
KR940702380A (ko) 1994-08-20
US5599789A (en) 1997-02-04
EP0620736A1 (de) 1994-10-26
WO1993012806A1 (en) 1993-07-08
JPH07502514A (ja) 1995-03-16
CA2104576C (en) 1997-04-15
EP0620736A4 (en) 1995-09-06
EP0620736B1 (de) 2001-03-07
DE69231726D1 (de) 2001-04-12
AU3251693A (en) 1993-07-28
CA2104576A1 (en) 1993-06-25

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