ATE196465T1 - Analoge von difluoro-staton - Google Patents
Analoge von difluoro-statonInfo
- Publication number
- ATE196465T1 ATE196465T1 AT94920095T AT94920095T ATE196465T1 AT E196465 T1 ATE196465 T1 AT E196465T1 AT 94920095 T AT94920095 T AT 94920095T AT 94920095 T AT94920095 T AT 94920095T AT E196465 T1 ATE196465 T1 AT E196465T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- difluoro
- staton
- analogue
- sec
- Prior art date
Links
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- PQIOSYKVBBWRRI-UHFFFAOYSA-N methylphosphonyl difluoride Chemical group CP(F)(F)=O PQIOSYKVBBWRRI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Air Bags (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93401785 | 1993-07-08 | ||
| PCT/US1994/006376 WO1995001958A1 (en) | 1993-07-08 | 1994-06-07 | Difluoro statone analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196465T1 true ATE196465T1 (de) | 2000-10-15 |
Family
ID=8214732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94920095T ATE196465T1 (de) | 1993-07-08 | 1994-06-07 | Analoge von difluoro-staton |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5717093A (enExample) |
| EP (1) | EP0707564B1 (enExample) |
| JP (1) | JPH08512319A (enExample) |
| KR (1) | KR100316864B1 (enExample) |
| CN (1) | CN1126988A (enExample) |
| AT (1) | ATE196465T1 (enExample) |
| AU (1) | AU680009B2 (enExample) |
| CA (1) | CA2166693C (enExample) |
| DE (1) | DE69425971T2 (enExample) |
| ES (1) | ES2152982T3 (enExample) |
| FI (1) | FI120389B (enExample) |
| HU (1) | HUT73411A (enExample) |
| IL (1) | IL110227A0 (enExample) |
| NO (1) | NO306343B1 (enExample) |
| NZ (1) | NZ268202A (enExample) |
| TW (1) | TW288005B (enExample) |
| WO (1) | WO1995001958A1 (enExample) |
| ZA (1) | ZA944818B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69418050T2 (de) * | 1993-09-09 | 1999-11-25 | Merrell Pharmaceuticals Inc., Cincinnati | Antivirale analoge von difluorostaton |
| TW200910648A (en) | 2007-08-31 | 2009-03-01 | Isotech Products Inc | Forming process of resin lens of an LED component |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5066643A (en) * | 1985-02-19 | 1991-11-19 | Sandoz Ltd. | Fluorine and chlorine statine or statone containing peptides and method of use |
| CH672792A5 (enExample) * | 1985-02-19 | 1989-12-29 | Sandoz Ag | |
| WO1986006379A1 (en) * | 1985-04-19 | 1986-11-06 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
| GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
| NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
| FR2614533A1 (fr) * | 1987-04-23 | 1988-11-04 | Sandoz Sa | Nouveaux derives peptidiques, leur preparation et leur utilisation comme medicaments |
| GB2212158A (en) * | 1987-12-15 | 1989-07-19 | Sandoz Ltd | Trialkylsilymethyl-substituted peptides; renin inhibitors |
| AU3964489A (en) * | 1988-07-08 | 1990-02-05 | Smithkline Beckman Corporation | Retroviral protease binding peptides |
| IL90872A0 (en) | 1988-07-08 | 1990-02-09 | Smithkline Beckman Corp | Retroviral protease binding peptides |
| CA2010531A1 (en) * | 1989-03-06 | 1990-09-06 | Werner Neidhart | Amino acid derivatives |
| US5151438A (en) * | 1989-05-23 | 1992-09-29 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| CA2098020C (en) * | 1991-01-02 | 2003-10-21 | Daniel Schirlin | Anti-viral compounds |
| CA2131154A1 (en) * | 1992-03-25 | 1993-09-30 | Colin W. Greengrass | Antiviral peptides |
| GB9210744D0 (en) * | 1992-05-20 | 1992-07-08 | Pfizer Ltd | Antiviral peptides |
| EP0641325B1 (en) * | 1992-05-21 | 2001-03-07 | Monsanto Company | Retroviral protease inhibitors |
| EP0773926A1 (en) * | 1994-07-15 | 1997-05-21 | Merrell Pharmaceuticals Inc. | Difluorostatone antiviral agents |
| JP2015518386A (ja) | 2013-02-08 | 2015-07-02 | テイト タワーズ マニュファクチャリング、 エルエルシー | 視覚的に透明な可撓性支持部材を有する飛行プラットフォーム |
-
1994
- 1994-06-07 EP EP94920095A patent/EP0707564B1/en not_active Expired - Lifetime
- 1994-06-07 HU HU9503706A patent/HUT73411A/hu unknown
- 1994-06-07 NZ NZ268202A patent/NZ268202A/en unknown
- 1994-06-07 JP JP7504027A patent/JPH08512319A/ja active Pending
- 1994-06-07 CN CN94192700A patent/CN1126988A/zh active Pending
- 1994-06-07 KR KR1019960700062A patent/KR100316864B1/ko not_active Expired - Fee Related
- 1994-06-07 AT AT94920095T patent/ATE196465T1/de not_active IP Right Cessation
- 1994-06-07 US US08/578,698 patent/US5717093A/en not_active Expired - Lifetime
- 1994-06-07 WO PCT/US1994/006376 patent/WO1995001958A1/en not_active Ceased
- 1994-06-07 DE DE69425971T patent/DE69425971T2/de not_active Expired - Lifetime
- 1994-06-07 ES ES94920095T patent/ES2152982T3/es not_active Expired - Lifetime
- 1994-06-07 CA CA002166693A patent/CA2166693C/en not_active Expired - Fee Related
- 1994-06-07 AU AU71008/94A patent/AU680009B2/en not_active Ceased
- 1994-07-04 ZA ZA944818A patent/ZA944818B/xx unknown
- 1994-07-05 TW TW083106128A patent/TW288005B/zh active
- 1994-07-06 IL IL11022794A patent/IL110227A0/xx unknown
-
1996
- 1996-01-05 NO NO960048A patent/NO306343B1/no not_active IP Right Cessation
- 1996-01-05 FI FI960051A patent/FI120389B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2152982T3 (es) | 2001-02-16 |
| FI960051A0 (fi) | 1996-01-05 |
| HU9503706D0 (en) | 1996-02-28 |
| EP0707564B1 (en) | 2000-09-20 |
| NZ268202A (en) | 1997-09-22 |
| TW288005B (enExample) | 1996-10-11 |
| NO306343B1 (no) | 1999-10-25 |
| NO960048D0 (no) | 1996-01-05 |
| IL110227A0 (en) | 1994-10-21 |
| EP0707564A1 (en) | 1996-04-24 |
| WO1995001958A1 (en) | 1995-01-19 |
| HUT73411A (en) | 1996-07-29 |
| CA2166693A1 (en) | 1995-01-09 |
| US5717093A (en) | 1998-02-10 |
| KR100316864B1 (ko) | 2002-11-13 |
| AU680009B2 (en) | 1997-07-17 |
| FI120389B (fi) | 2009-10-15 |
| AU7100894A (en) | 1995-02-06 |
| CN1126988A (zh) | 1996-07-17 |
| DE69425971T2 (de) | 2001-05-23 |
| KR960703844A (ko) | 1996-08-31 |
| ZA944818B (en) | 1995-02-22 |
| NO960048L (no) | 1996-03-05 |
| FI960051L (fi) | 1996-03-07 |
| CA2166693C (en) | 1999-08-24 |
| DE69425971D1 (de) | 2000-10-26 |
| JPH08512319A (ja) | 1996-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |