ATE192337T1 - Hemmung der migration von glatten mushelzellen durch (r)-amlodipin - Google Patents

Hemmung der migration von glatten mushelzellen durch (r)-amlodipin

Info

Publication number
ATE192337T1
ATE192337T1 AT94926189T AT94926189T ATE192337T1 AT E192337 T1 ATE192337 T1 AT E192337T1 AT 94926189 T AT94926189 T AT 94926189T AT 94926189 T AT94926189 T AT 94926189T AT E192337 T1 ATE192337 T1 AT E192337T1
Authority
AT
Austria
Prior art keywords
pct
amlodipine
smooth muscle
cell migration
muscle cell
Prior art date
Application number
AT94926189T
Other languages
English (en)
Inventor
Suresh Babubhai Chahwala
Derek Paul Winslow
Original Assignee
Pfizer Ltd
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10741080&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE192337(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd, Pfizer Res & Dev filed Critical Pfizer Ltd
Application granted granted Critical
Publication of ATE192337T1 publication Critical patent/ATE192337T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT94926189T 1993-08-26 1994-08-10 Hemmung der migration von glatten mushelzellen durch (r)-amlodipin ATE192337T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939317773A GB9317773D0 (en) 1993-08-26 1993-08-26 Therapeutic compound
PCT/EP1994/002697 WO1995005822A1 (en) 1993-08-26 1994-08-10 Inhibition of smooth muscle cell migration by (r)-amlodipine

Publications (1)

Publication Number Publication Date
ATE192337T1 true ATE192337T1 (de) 2000-05-15

Family

ID=10741080

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94926189T ATE192337T1 (de) 1993-08-26 1994-08-10 Hemmung der migration von glatten mushelzellen durch (r)-amlodipin

Country Status (20)

Country Link
US (1) US6080761A (de)
EP (1) EP0754043B1 (de)
JP (2) JP3007992B2 (de)
KR (1) KR0163840B1 (de)
CN (1) CN1060039C (de)
AT (1) ATE192337T1 (de)
AU (1) AU686658B2 (de)
CA (1) CA2170278C (de)
DE (1) DE69424317T2 (de)
DK (1) DK0754043T3 (de)
ES (1) ES2145149T3 (de)
GB (1) GB9317773D0 (de)
GR (1) GR3033547T3 (de)
IL (1) IL110700A (de)
NO (1) NO308826B1 (de)
NZ (1) NZ271993A (de)
PT (1) PT754043E (de)
TW (1) TW470646B (de)
WO (1) WO1995005822A1 (de)
ZA (1) ZA946475B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7129265B2 (en) * 1999-04-23 2006-10-31 Mason R Preston Synergistic effects of amlodipine and atorvastatin metabolite as a basis for combination therapy
GB0020842D0 (en) * 2000-08-23 2000-10-11 Pfizer Ltd Therapeutic compositions
US6737430B2 (en) 2000-11-09 2004-05-18 Pfizer, Inc. Mutual prodrug of amlodipine and atorvastatin
AT5874U1 (de) * 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
EP1345901A2 (de) * 2000-12-29 2003-09-24 Bioorganics B.V. Herstellungsverfahren für amlodipin und ihre precursor und derivate
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
CN1152013C (zh) * 2001-11-22 2004-06-02 张喜田 一类左旋氨氯地平盐的水合物及其制剂
US7858801B2 (en) * 2004-10-20 2010-12-28 Emcure Pharmaceuticals Limited Process for producing enantiomer of amlodipine in high optical purity
KR100828883B1 (ko) * 2006-10-27 2008-05-09 씨제이제일제당 (주) 라세믹 암로디핀으로부터 ｓ-(-)-암로디핀의 분리방법
KR100830003B1 (ko) * 2006-10-31 2008-05-15 씨제이제일제당 (주) 결정성 ｓ-(-)-암로디핀 아디핀산 염 무수물 및 이의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8804630D0 (en) * 1988-02-27 1988-03-30 Pfizer Ltd Preparation of r-& s-amlodipine
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine

Also Published As

Publication number Publication date
EP0754043A1 (de) 1997-01-22
KR0163840B1 (ko) 1998-12-01
EP0754043B1 (de) 2000-05-03
NO308826B1 (no) 2000-11-06
JP3007992B2 (ja) 2000-02-14
NO960730L (no) 1996-02-23
DE69424317T2 (de) 2000-08-24
KR960703593A (ko) 1996-08-31
AU7612994A (en) 1995-03-21
JPH08509004A (ja) 1996-09-24
CN1060039C (zh) 2001-01-03
DE69424317D1 (de) 2000-06-08
AU686658B2 (en) 1998-02-12
JP2000044475A (ja) 2000-02-15
ZA946475B (en) 1996-02-26
PT754043E (pt) 2000-09-29
NZ271993A (en) 1997-11-24
TW470646B (en) 2002-01-01
NO960730D0 (no) 1996-02-23
CA2170278A1 (en) 1995-03-02
DK0754043T3 (da) 2000-08-07
GR3033547T3 (en) 2000-09-29
ES2145149T3 (es) 2000-07-01
IL110700A (en) 1999-04-11
WO1995005822A1 (en) 1995-03-02
CA2170278C (en) 1999-08-03
GB9317773D0 (en) 1993-10-13
US6080761A (en) 2000-06-27
CN1129907A (zh) 1996-08-28
IL110700A0 (en) 1994-11-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee