ATE190614T1 - Dihydrat des n-(4-amino-6,7-dimethoxychinazol-2- yl)-n-methyl-n'-(tetrahydrofuroyl-2)- propylendiamin hydrochlorids(=alfuzosin hydrochlorid dihydrat) und ein verfahren zur herstellung - Google Patents
Dihydrat des n-(4-amino-6,7-dimethoxychinazol-2- yl)-n-methyl-n'-(tetrahydrofuroyl-2)- propylendiamin hydrochlorids(=alfuzosin hydrochlorid dihydrat) und ein verfahren zur herstellungInfo
- Publication number
- ATE190614T1 ATE190614T1 AT94120539T AT94120539T ATE190614T1 AT E190614 T1 ATE190614 T1 AT E190614T1 AT 94120539 T AT94120539 T AT 94120539T AT 94120539 T AT94120539 T AT 94120539T AT E190614 T1 ATE190614 T1 AT E190614T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydrate
- hydrochloride
- dimethoxychinazol
- tetrahydrofuroyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5353828A JPH07206857A (ja) | 1993-12-28 | 1993-12-28 | アルフゾシン塩酸塩の二水和物 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE190614T1 true ATE190614T1 (de) | 2000-04-15 |
Family
ID=18433498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94120539T ATE190614T1 (de) | 1993-12-28 | 1994-12-23 | Dihydrat des n-(4-amino-6,7-dimethoxychinazol-2- yl)-n-methyl-n'-(tetrahydrofuroyl-2)- propylendiamin hydrochlorids(=alfuzosin hydrochlorid dihydrat) und ein verfahren zur herstellung |
Country Status (6)
Country | Link |
---|---|
US (1) | US5545738A (de) |
EP (1) | EP0663398B1 (de) |
JP (1) | JPH07206857A (de) |
KR (1) | KR100329156B1 (de) |
AT (1) | ATE190614T1 (de) |
DE (1) | DE69423459T2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0849265A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von Doxazosin-Mesylat (Form II) |
GB9708917D0 (en) * | 1997-05-01 | 1997-06-25 | Pfizer Ltd | Compounds useful in therapy |
DE19951418A1 (de) * | 1999-10-26 | 2001-05-03 | Merck Patent Gmbh | Verfahren zur Herstellung von N-(4,5-Bismethansulfonyl-2-methyl-benzoyl) -guanidin, Hydrochlorid |
DE10232113A1 (de) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
PL1789412T3 (pl) * | 2004-09-16 | 2008-10-31 | Hetero Drugs Ltd | Krystaliczna zasada alfuzosyny |
US20070049756A1 (en) * | 2005-08-30 | 2007-03-01 | Anumula Raghupathi R | Alfuzosin hydrochloride polymorphs |
WO2007069050A2 (en) * | 2005-12-16 | 2007-06-21 | Wockhardt Ltd. | Processes for the preparation of alfuzosin |
US20100092556A1 (en) * | 2006-12-11 | 2010-04-15 | Kristin Arnold | Alfuzosin formulations, methods of making, and methods of use |
US20080160081A1 (en) * | 2006-12-11 | 2008-07-03 | Mutual Pharmaceutical Company, Inc. | Alfuzosin formulations, methods of making, and methods of use |
WO2008114272A2 (en) * | 2007-03-22 | 2008-09-25 | Cadila Healthcare Limited | Process for preparing alpuzosin and crystalline alfuzosin hydrochloride |
EP2152697A2 (de) | 2007-05-04 | 2010-02-17 | Actavis Group PTC EHF | Verfahren zur herstellung von alfuzosin und salzen daraus |
KR20100044239A (ko) * | 2007-08-02 | 2010-04-29 | 시플라 리미티드 | 알푸조신 염산염의 제조방법 |
UA102128C2 (en) * | 2008-12-05 | 2013-06-10 | Х. Луннбек А/С | Nalmefene hydrochloride dihydrate |
WO2010083360A2 (en) * | 2009-01-16 | 2010-07-22 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations |
CN114674967B (zh) * | 2022-03-25 | 2022-10-04 | 邦恩泰(山东)生物医药科技集团股份有限公司 | N-甲基-n′-四氢呋喃甲酰基丙二胺草酸盐有关物质的检测方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
FR2421888A1 (fr) * | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
FI79107C (fi) * | 1984-06-25 | 1989-11-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid. |
US4925837A (en) * | 1984-09-14 | 1990-05-15 | Synthelabo | Pharmaceutical compositions |
FR2582513B1 (fr) * | 1985-05-28 | 1988-08-05 | Synthelabo | Compositions pharmaceutiques contenant de l'alfuzosine |
US5294615A (en) * | 1993-04-29 | 1994-03-15 | Abbott Laboratories | Terazosin polymorph and pharmaceutical composition |
-
1993
- 1993-12-28 JP JP5353828A patent/JPH07206857A/ja active Pending
-
1994
- 1994-12-23 EP EP94120539A patent/EP0663398B1/de not_active Expired - Lifetime
- 1994-12-23 AT AT94120539T patent/ATE190614T1/de not_active IP Right Cessation
- 1994-12-23 DE DE69423459T patent/DE69423459T2/de not_active Expired - Lifetime
- 1994-12-27 KR KR1019940037437A patent/KR100329156B1/ko not_active IP Right Cessation
- 1994-12-27 US US08/364,180 patent/US5545738A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH07206857A (ja) | 1995-08-08 |
EP0663398A1 (de) | 1995-07-19 |
KR100329156B1 (ko) | 2002-11-22 |
US5545738A (en) | 1996-08-13 |
DE69423459T2 (de) | 2000-10-26 |
EP0663398B1 (de) | 2000-03-15 |
KR950017992A (ko) | 1995-07-22 |
DE69423459D1 (de) | 2000-04-20 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |