ATE1903T1 - Neue 3,4-disubstituierte 2-phenyliminoimidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung. - Google Patents
Neue 3,4-disubstituierte 2-phenyliminoimidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung.Info
- Publication number
- ATE1903T1 ATE1903T1 AT79104381T AT79104381T ATE1903T1 AT E1903 T1 ATE1903 T1 AT E1903T1 AT 79104381 T AT79104381 T AT 79104381T AT 79104381 T AT79104381 T AT 79104381T AT E1903 T1 ATE1903 T1 AT E1903T1
- Authority
- AT
- Austria
- Prior art keywords
- fluoro
- group
- methylphenyl
- disubstituted
- see diagramm
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 150000003839 salts Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 3,4-Disubstituted 2-phenylimino-imidazolidines Chemical class 0.000 abstract 12
- 238000007792 addition Methods 0.000 abstract 4
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- HKWFCVUHNYCCNR-UHFFFAOYSA-N 1-n-(4,5-dihydro-1h-imidazol-2-yl)-4-fluorobenzene-1,3-diamine Chemical compound C1=C(F)C(N)=CC(N=C2NCCN2)=C1 HKWFCVUHNYCCNR-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- NHDLMBUAIWPQQA-UHFFFAOYSA-N n-(4-fluoro-3-nitrophenyl)-4,5-dihydro-1h-imidazol-2-amine Chemical compound C1=C(F)C([N+](=O)[O-])=CC(NC=2NCCN=2)=C1 NHDLMBUAIWPQQA-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782854659 DE2854659A1 (de) | 1978-12-18 | 1978-12-18 | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| EP79104381A EP0012822B1 (de) | 1978-12-18 | 1979-11-08 | Neue 3,4-disubstituierte 2-Phenylimino-imidazolidine, deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE1903T1 true ATE1903T1 (de) | 1982-12-15 |
Family
ID=6057553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79104381T ATE1903T1 (de) | 1978-12-18 | 1979-11-08 | Neue 3,4-disubstituierte 2-phenyliminoimidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung. |
Country Status (18)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2933930A1 (de) * | 1979-08-22 | 1981-03-12 | C.H. Boehringer Sohn, 6507 Ingelheim | 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben. |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
| AU704972B2 (en) | 1994-08-04 | 1999-05-13 | H. Lundbeck A/S | Novel benzimidazole derivatives |
| DE19514579A1 (de) | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
| CO4910165A1 (es) * | 1996-11-25 | 2000-04-24 | Procter & Gamble | Procedimiento para elaboracion de derivados de 2-amino-2- imidazolina, guanidina y 2-amino-3,4,5,6-tetrahidropirimidi- na |
| US6495583B1 (en) | 1997-03-25 | 2002-12-17 | Synaptic Pharmaceutical Corporation | Benzimidazole derivatives |
| US6066740A (en) * | 1997-11-25 | 2000-05-23 | The Procter & Gamble Company | Process for making 2-amino-2-imidazoline, guanidine and 2-amino-3,4,5,6-tetrahydropyrimidine derivatives |
| CN111303038A (zh) * | 2020-03-18 | 2020-06-19 | 滨州德润化工有限责任公司 | 一种油田水处理用缓蚀剂两性咪唑啉制作工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL123037C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1963-10-04 | |||
| SE331280B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1965-10-01 | 1970-12-21 | Boehringer Sohn Ingelheim | |
| DE1545628A1 (de) * | 1965-10-01 | 1970-06-25 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2) |
| AT278775B (de) * | 1967-01-19 | 1970-02-10 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von Δ<2>-Imidazolinderivaten und ihren Salzen |
| AT330769B (de) * | 1974-04-05 | 1976-07-26 | Chemie Linz Ag | Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen |
| DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
-
1978
- 1978-12-18 DE DE19782854659 patent/DE2854659A1/de not_active Withdrawn
-
1979
- 1979-11-08 AT AT79104381T patent/ATE1903T1/de not_active IP Right Cessation
- 1979-11-08 DE DE7979104381T patent/DE2964166D1/de not_active Expired
- 1979-11-08 EP EP79104381A patent/EP0012822B1/de not_active Expired
- 1979-11-28 GR GR60628A patent/GR73913B/el unknown
- 1979-12-13 PT PT70592A patent/PT70592A/pt unknown
- 1979-12-17 ES ES486971A patent/ES486971A0/es active Granted
- 1979-12-17 ES ES486970A patent/ES8102100A1/es not_active Expired
- 1979-12-17 YU YU3089/79A patent/YU41901B/xx unknown
- 1979-12-17 IE IE2447/79A patent/IE49239B1/en unknown
- 1979-12-17 JP JP16289679A patent/JPS5583754A/ja active Granted
- 1979-12-17 AU AU53893/79A patent/AU526539B2/en not_active Ceased
- 1979-12-17 FI FI793948A patent/FI68814C/fi not_active IP Right Cessation
- 1979-12-17 IL IL58971A patent/IL58971A/xx unknown
- 1979-12-17 ES ES486967A patent/ES8103054A1/es not_active Expired
- 1979-12-17 DK DK537179A patent/DK146821C/da not_active IP Right Cessation
- 1979-12-17 NZ NZ192426A patent/NZ192426A/en unknown
- 1979-12-17 NO NO794114A patent/NO148555C/no unknown
- 1979-12-17 CA CA342,041A patent/CA1112648A/en not_active Expired
- 1979-12-18 ZA ZA00796832A patent/ZA796832B/xx unknown
-
1983
- 1983-03-22 PH PH28680A patent/PH22130A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |