ATE188692T1 - Fibrinogenrezeptorantagonisten - Google Patents

Fibrinogenrezeptorantagonisten

Info

Publication number
ATE188692T1
ATE188692T1 AT94913969T AT94913969T ATE188692T1 AT E188692 T1 ATE188692 T1 AT E188692T1 AT 94913969 T AT94913969 T AT 94913969T AT 94913969 T AT94913969 T AT 94913969T AT E188692 T1 ATE188692 T1 AT E188692T1
Authority
AT
Austria
Prior art keywords
receptor antagonists
fibrinogen receptor
fibrinogen
image
blood platelets
Prior art date
Application number
AT94913969T
Other languages
English (en)
Inventor
David A Claremon
Nigel Liverton
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE188692T1 publication Critical patent/ATE188692T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT94913969T 1993-04-05 1994-03-29 Fibrinogenrezeptorantagonisten ATE188692T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/042,963 US5441952A (en) 1993-04-05 1993-04-05 Fibrinogen receptor antagonists
PCT/US1994/003400 WO1994022825A1 (en) 1993-04-05 1994-03-29 Fibrinogen receptor antagonists

Publications (1)

Publication Number Publication Date
ATE188692T1 true ATE188692T1 (de) 2000-01-15

Family

ID=21924701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94913969T ATE188692T1 (de) 1993-04-05 1994-03-29 Fibrinogenrezeptorantagonisten

Country Status (8)

Country Link
US (1) US5441952A (de)
EP (1) EP0693067B1 (de)
JP (1) JPH08508501A (de)
AT (1) ATE188692T1 (de)
AU (1) AU683882B2 (de)
CA (1) CA2159482A1 (de)
DE (1) DE69422615T2 (de)
WO (1) WO1994022825A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11505509A (ja) * 1994-12-09 1999-05-21 スミスクライン・ビーチャム・コーポレイション 二環式フィブリノーゲン拮抗薬
ES2227612T3 (es) 1995-09-29 2005-04-01 Eli Lilly And Company Compuestos espiro como inhibidores de agregacion plaquetaria dependiente del fibrinogeno.
US6011029A (en) * 1996-02-26 2000-01-04 Bristol-Myers Squibb Company Inhibitors of farnesyl protein transferase
ES2271971T3 (es) * 1996-07-25 2007-04-16 Biogen Idec Ma Inc. Inhibidores de la adhesion celular.
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
KR100565701B1 (ko) * 1997-07-31 2006-03-29 우베 고산 가부시키가이샤 Ｎ-아실아미노산 아미드 화합물 및 그의 제조 중간체
US6623981B2 (en) * 1998-01-27 2003-09-23 Bristol-Myers Squibb Company Detection of patients at risk for developing integrin antagonist/agonist mediated disease states
DK1443937T3 (da) 2001-11-13 2008-10-20 Ortho Mcneil Pharm Inc Substituerede 1,4-benzodiazepiner samt deres anvendelse til behnadling af cancer
EP1591120A4 (de) * 2003-01-28 2009-06-10 Takeda Chemical Industries Ltd Rezeptor-agonisten
ES2671748T3 (es) 2011-07-21 2018-06-08 Tolero Pharmaceuticals, Inc. Inhibidores heterocíclicos de proteína quinasas
CA3127502A1 (en) 2019-02-12 2020-08-20 Sumitomo Dainippon Pharma Oncology, Inc. Formulations comprising heterocyclic protein kinase inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313947A (en) * 1974-06-24 1982-02-02 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use
DE2549999A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Piperidin-derivate und verfahren zu ihrer herstellung
US4064125A (en) * 1976-10-29 1977-12-20 E. R. Squibb And Sons, Inc. Substituted amides having antiinflammatory activity
IL60129A0 (en) * 1979-05-23 1980-07-31 Wuelfing J Kg Phenylsulphonamide derivatives,their preparation and pharmaceutical compositions containing them
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
KR880007441A (ko) * 1986-12-11 1988-08-27 알렌 제이.스피겔 스피로-치환된 글루타르아미드 이뇨제
US4879313A (en) * 1988-07-20 1989-11-07 Mosanto Company Novel platelet-aggregation inhibitors
US5039805A (en) * 1988-12-08 1991-08-13 Hoffmann-La Roche Inc. Novel benzoic and phenylacetic acid derivatives
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
CA2008116C (en) * 1989-02-23 2001-11-20 Thomas Weller Glycine derivatives
NZ234264A (en) * 1989-06-29 1993-05-26 Warner Lambert Co N-substituted cycloalkyl and polycycloalkyl alpha-substituted trp-phe- and phenethylamine derivatives, and pharmaceutical compositions
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
NZ243326A (en) * 1991-06-28 1995-10-26 Smithkline Beecham Corp Benzodiazepine, benzazepine; benzothiazepine and benzoxazepine derivatives; pharmaceutical compositions

Also Published As

Publication number Publication date
AU683882B2 (en) 1997-11-27
DE69422615D1 (de) 2000-02-17
EP0693067A1 (de) 1996-01-24
US5441952A (en) 1995-08-15
JPH08508501A (ja) 1996-09-10
DE69422615T2 (de) 2000-08-03
EP0693067B1 (de) 2000-01-12
AU6621894A (en) 1994-10-24
CA2159482A1 (en) 1994-10-13
WO1994022825A1 (en) 1994-10-13
EP0693067A4 (de) 1995-12-12

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Legal Events

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