ATE182623T1 - Humanes serum albumin, herstellung und verwendung - Google Patents

Humanes serum albumin, herstellung und verwendung

Info

Publication number
ATE182623T1
ATE182623T1 AT93904116T AT93904116T ATE182623T1 AT E182623 T1 ATE182623 T1 AT E182623T1 AT 93904116 T AT93904116 T AT 93904116T AT 93904116 T AT93904116 T AT 93904116T AT E182623 T1 ATE182623 T1 AT E182623T1
Authority
AT
Austria
Prior art keywords
pct
production
serum albumin
human serum
sec
Prior art date
Application number
AT93904116T
Other languages
English (en)
Inventor
Jerome Becquart
Reinhard Fleer
Gerard Jung
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9425981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE182623(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE182623T1 publication Critical patent/ATE182623T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AT93904116T 1992-01-27 1993-01-26 Humanes serum albumin, herstellung und verwendung ATE182623T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9200807A FR2686620B1 (fr) 1992-01-27 1992-01-27 Serum-albumine humaine, preparation et utilisation.

Publications (1)

Publication Number Publication Date
ATE182623T1 true ATE182623T1 (de) 1999-08-15

Family

ID=9425981

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93904116T ATE182623T1 (de) 1992-01-27 1993-01-26 Humanes serum albumin, herstellung und verwendung

Country Status (16)

Country Link
US (1) US5612196A (de)
EP (1) EP0625202B1 (de)
JP (1) JP3390990B2 (de)
AT (1) ATE182623T1 (de)
AU (1) AU686996B2 (de)
CA (1) CA2126356C (de)
DE (1) DE69325794T2 (de)
DK (1) DK0625202T3 (de)
ES (1) ES2137251T3 (de)
FI (1) FI943512A (de)
FR (1) FR2686620B1 (de)
GR (1) GR3030873T3 (de)
HU (1) HU218353B (de)
NO (1) NO310418B1 (de)
NZ (1) NZ249153A (de)
WO (1) WO1993015204A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
CA2136564C (en) * 1993-11-26 2008-04-08 Kaoru Kobayashi Process for producing human serum albumin
GB9526733D0 (en) * 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP2003531590A (ja) 2000-04-12 2003-10-28 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
US6762053B2 (en) * 2000-06-09 2004-07-13 Vitrolife, Inc. Mammalian gamete and embryo culture media and culture media supplements
US20050244931A1 (en) * 2001-04-12 2005-11-03 Human Genome Sciences, Inc. Albumin fusion proteins
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US20060084794A1 (en) * 2001-04-12 2006-04-20 Human Genome Sciences, Inc. Albumin fusion proteins
WO2003030821A2 (en) * 2001-10-05 2003-04-17 Human Genome Sciences, Inc. Albumin fusion proteins
EP1463752A4 (de) 2001-12-21 2005-07-13 Human Genome Sciences Inc Albuminfusionsproteine
EP1997829A1 (de) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin Fusionsproteine
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
SI1729795T1 (sl) * 2004-02-09 2016-04-29 Human Genome Sciences, Inc. Albuminski fuzijski proteini
EP2169067A1 (de) * 2004-12-22 2010-03-31 Novozymes A/S Rekombinante Serumalbuminproduktion
BRPI0921586A2 (pt) 2008-11-18 2019-09-24 Merrimack Pharmaceuticals Inc articuladores de albumina de soro humana e conjugados destes
CN102127164B (zh) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
EP2729492B1 (de) 2011-07-05 2019-01-02 Albumedix Ltd Albuminformulierung und verwendung
WO2014036520A1 (en) 2012-08-30 2014-03-06 Merrimack Pharmaceuticals, Inc. Combination therapies comprising anti-erbb3 agents
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
EP3240798B8 (de) * 2015-01-01 2020-03-25 Shilpa Medicare Limited Neuartiges verfahren zur effizienten aufreinigung von humanem serumalbumin
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
WO2024018452A1 (en) 2022-07-18 2024-01-25 Yeda Research And Development Co. Ltd. Albumin protein variants, production thereof and uses of same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
FR2635115B1 (fr) * 1988-08-05 1992-04-03 Rhone Poulenc Sante Procede de preparation de la serum albumine humaine a partir d'une levure
FR2649991B2 (fr) * 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
GB8923521D0 (en) * 1989-10-18 1989-12-06 Delta Biotechnology Ltd Yeast promoter
JP3230091B2 (ja) * 1990-06-25 2001-11-19 ウェルファイド株式会社 ヒト血清アルブミンの着色抑制方法
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
FR2677996B1 (fr) * 1991-06-21 1993-08-27 Rhone Poulenc Rorer Sa Vecteurs de clonage et/ou d'expression preparation et utilisation.

Also Published As

Publication number Publication date
FI943512A0 (fi) 1994-07-26
AU3503893A (en) 1993-09-01
EP0625202B1 (de) 1999-07-28
NO310418B1 (no) 2001-07-02
NO942780L (no) 1994-07-26
HUT70570A (en) 1995-10-30
FR2686620A1 (fr) 1993-07-30
NO942780D0 (no) 1994-07-26
CA2126356C (fr) 2003-03-18
FI943512A (fi) 1994-07-26
ES2137251T3 (es) 1999-12-16
FR2686620B1 (fr) 1995-06-23
JP3390990B2 (ja) 2003-03-31
JPH07503137A (ja) 1995-04-06
WO1993015204A1 (fr) 1993-08-05
DE69325794T2 (de) 2000-01-13
GR3030873T3 (en) 1999-11-30
HU9401960D0 (en) 1994-09-28
AU686996B2 (en) 1998-02-19
US5612196A (en) 1997-03-18
DE69325794D1 (de) 1999-09-02
HU218353B (hu) 2000-08-28
CA2126356A1 (fr) 1993-08-05
DK0625202T3 (da) 2000-02-28
NZ249153A (en) 1996-03-26
EP0625202A1 (de) 1994-11-23

Similar Documents

Publication Publication Date Title
ATE182623T1 (de) Humanes serum albumin, herstellung und verwendung
NO965621D0 (no) Nye hIL-4-mutantproteiner som antagonister eller partielle agonister for det humane interleukin 4
ATE198624T1 (de) Expression von albumin in hefe
AU5914590A (en) Muteins of human erythropoietin, the preparation thereof and the use thereof
DE59610632D1 (de) Varianten des humanen rekombinanten interferon-gamma (rhu-ifn-gamma) mit erhöhter thermischer stabilität
DE59712852D1 (de) Parapockenviren, die fremd-dna enthalten, ihre herstellung und ihre verwendung in impfstoffen
DE69315341T2 (de) Antigene regionen von tumorfreigestzten partikeln (tlp) komplexen und antikörper die sie erkennen.
DE69302375D1 (de) Kosmetische zusammensetzung zur erhaltung der frisur enthaltend ein milchprotein und/oder ein milchproteinhydrolysate und ein hydrolysate
AU669149B2 (en) Expression signal-peptide-free staphylokinases
DE69734596D1 (de) "smoothened" proteine aus wirbeltieren
ES2071343T3 (es) Nuevos peptidos con actividad anticoagulatoria.
DE69213660D1 (de) Verwendung von 1-(beta-d-arabinofuranosyl)-5-propynyluracil zur senkung des serumcholesterins
DE69425061D1 (de) Verwendung von einer suspension auf der basis von sucralfatgel als antazidum
DE58909261D1 (de) Ancrod-proteine, ihre herstellung und verwendung.
DE69323191D1 (de) Wasserlösliche retinoide

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee