ATE18236T1 - Chemische verbindungen und verwendung als suessstoff. - Google Patents

Chemische verbindungen und verwendung als suessstoff.

Info

Publication number
ATE18236T1
ATE18236T1 AT83420149T AT83420149T ATE18236T1 AT E18236 T1 ATE18236 T1 AT E18236T1 AT 83420149 T AT83420149 T AT 83420149T AT 83420149 T AT83420149 T AT 83420149T AT E18236 T1 ATE18236 T1 AT E18236T1
Authority
AT
Austria
Prior art keywords
group
lone
carbon atoms
electron pair
pair donor
Prior art date
Application number
AT83420149T
Other languages
German (de)
English (en)
Inventor
Claude Nofre
Jean-Marie Tinti
Original Assignee
Univ Claude Bernard Lyon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Claude Bernard Lyon filed Critical Univ Claude Bernard Lyon
Application granted granted Critical
Publication of ATE18236T1 publication Critical patent/ATE18236T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Tea And Coffee (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
AT83420149T 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff. ATE18236T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8215832A FR2533210A1 (fr) 1982-09-17 1982-09-17 Edulcorants de synthese
EP83420149A EP0107597B1 (fr) 1982-09-17 1983-09-15 Composés chimiques et utilisation comme édulcorants

Publications (1)

Publication Number Publication Date
ATE18236T1 true ATE18236T1 (de) 1986-03-15

Family

ID=9277590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83420149T ATE18236T1 (de) 1982-09-17 1983-09-15 Chemische verbindungen und verwendung als suessstoff.

Country Status (16)

Country Link
US (1) US4645678A (https=)
EP (1) EP0107597B1 (https=)
JP (1) JPS5973559A (https=)
AT (1) ATE18236T1 (https=)
AU (1) AU562104B2 (https=)
CA (1) CA1244007A (https=)
DE (1) DE3362324D1 (https=)
DK (1) DK424783A (https=)
ES (1) ES525680A0 (https=)
FR (1) FR2533210A1 (https=)
GR (1) GR81273B (https=)
IL (1) IL69733A0 (https=)
NO (1) NO158418C (https=)
NZ (1) NZ205616A (https=)
PT (1) PT77351B (https=)
ZA (1) ZA836892B (https=)

Families Citing this family (59)

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FR2575163B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
US4833128A (en) * 1984-12-28 1989-05-23 Neil Solomon Dietary supplement
FR2606404B2 (fr) * 1986-04-10 1991-11-22 Univ Claude Bernard Lyon Nouveaux composes chimiques derivant de l'acide phenylguanidinoacetique et leur utilisation comme agents edulcorants
FR2608379B1 (fr) * 1986-12-23 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides n-phenylguanidinoacetique et n-phenylethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
JPS61260052A (ja) * 1985-05-14 1986-11-18 Ajinomoto Co Inc 新規アミノ酸誘導体および甘味剤
KR870008526A (ko) * 1986-03-13 1987-10-19 원본미기재 감미료 및 그 제조방법
US4818899A (en) * 1986-12-03 1989-04-04 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives
FR2609603B1 (fr) * 1987-01-15 1989-03-24 Univ Claude Bernard Lyon Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants
KR970002877B1 (ko) * 1987-07-17 1997-03-12 더 누트라스웨트 캄파니 고성능 감미제
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
FR2624698A1 (fr) * 1987-12-18 1989-06-23 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
WO1990002112A1 (en) * 1988-08-23 1990-03-08 The Nutrasweet Company Substituted aryl ureas as high potency sweeteners
US4994490A (en) * 1989-04-03 1991-02-19 The Nutrasweet Company Novel N-(sulfomethyl)-N'-arylureas
US5266717A (en) * 1989-04-03 1993-11-30 Glenn Roy N-(sulfomethyl)-N'arylureas
FR2653303B1 (fr) * 1989-10-24 1992-09-18 Noffre Claude Agents edulcorants de grande stabilite derivant des acides l-aspartique et l-glutamique n-hydrocarbones 1-oxo-2-ramifies.
AU639081B2 (en) * 1990-02-09 1993-07-15 Rhone-Poulenc Rorer S.A. N-phenyl n-acetamido glycinamides, preparation method and drugs containing them
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
AU4891396A (en) * 1995-03-14 1996-10-02 Daiichi Pharmaceutical Co., Ltd. Aminophenol derivatives
MY121054A (en) * 1998-04-08 2005-12-30 Smithkline Beecham Corp Calcilytic compounds as calcium receptor antagonists.
JP3959964B2 (ja) * 1998-04-09 2007-08-15 味の素株式会社 アスパルチルジペプチドエステル誘導体及び甘味剤
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
AU7822398A (en) * 1998-06-05 1999-12-20 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
EP1088829A4 (en) * 1998-06-26 2005-02-02 Ajinomoto Kk NEW ASPARTYL DIPETPID ESTER AND SWEETENING DERIVATIVES
SK3682001A3 (en) 1998-09-18 2001-10-08 Ajinomoto Kk N-alkylaspartyldipeptide ester derivatives and sweeteners
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
AR030684A1 (es) * 2000-01-24 2003-09-03 Smithkline Beecham Corp Compuestos calciliticos, uso de dichos compuestos en la manufactura de medicamentos, e intermediarios utiles en la preparacion de dichos compuestos
BRPI0413347A (pt) 2003-08-06 2006-10-10 Senomyx Inc novos sabores, modificadores de sabor, agentes de sabor, realçadores de sabor, agentes de sabor e/ou realçadores umami ou doces, e utilização correspondente
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
MX2007009388A (es) 2005-02-04 2007-09-25 Senomyx Inc Compuestos que comprenden porciones heteroarilo unidas y su uso como modificadores del sabor unami, saborizantes y mejoradores del sabor para composiciones comestibles.
TW200638882A (en) * 2005-02-04 2006-11-16 Senomyx Inc Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
TW200715993A (en) * 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
US8945652B2 (en) * 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8940350B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US8367138B2 (en) * 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US8940351B2 (en) * 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
AU2006318781B2 (en) * 2005-11-23 2012-11-01 The Coca-Cola Company Natural high-potency sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses
US8435588B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US9101160B2 (en) * 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
KR101387563B1 (ko) 2006-04-21 2014-04-25 세노믹스, 인코포레이티드 고효능의 조미용 향료를 포함하는 식품 조성물 및 이의 제조 방법
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
JP5647790B2 (ja) 2007-11-16 2015-01-07 株式会社カネカ N−カルバモイル−tert−ロイシンの製造法
AU2012329098B2 (en) 2011-10-26 2017-08-03 Allergan, Inc. Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators
RU2696581C2 (ru) * 2013-07-16 2019-08-05 Аллерган, Инк. Производные n-мочевинозамещенных аминокислот как модуляторы формил-пептидного рецептора
WO2015179707A1 (en) 2014-05-21 2015-11-26 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US3800046A (en) * 1967-04-17 1974-03-26 Searle & Co Artificially sweetened consumable products
GB1258248A (https=) * 1968-07-17 1971-12-22
US3642491A (en) * 1970-01-12 1972-02-15 Searle & Co Artificially sweetened consumable products
CA1027113A (en) * 1973-04-02 1978-02-28 General Foods Corporation Sweetener solution containing saccharin and aspartane
NL8005006A (nl) * 1980-09-04 1982-04-01 Stamicarbon Dipeptide-zoetstof.

Also Published As

Publication number Publication date
ES8406423A1 (es) 1984-07-01
GR81273B (https=) 1984-12-11
NZ205616A (en) 1986-03-14
JPS5973559A (ja) 1984-04-25
CA1244007A (fr) 1988-11-01
ES525680A0 (es) 1984-07-01
FR2533210A1 (fr) 1984-03-23
AU1916583A (en) 1984-03-22
EP0107597A1 (fr) 1984-05-02
EP0107597B1 (fr) 1986-02-26
DK424783D0 (da) 1983-09-16
DK424783A (da) 1984-03-18
NO833338L (no) 1984-03-19
NO158418B (no) 1988-05-30
PT77351B (fr) 1986-03-18
FR2533210B1 (https=) 1984-11-23
DE3362324D1 (en) 1986-04-03
ZA836892B (en) 1984-05-30
IL69733A0 (en) 1983-12-30
PT77351A (fr) 1983-10-01
US4645678A (en) 1987-02-24
AU562104B2 (en) 1987-05-28
NO158418C (no) 1988-09-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee