ATE180479T1 - Sulfonat- und carbamatderivate von 3-aroyl- benzo(beta)thiophenen - Google Patents

Sulfonat- und carbamatderivate von 3-aroyl- benzo(beta)thiophenen

Info

Publication number
ATE180479T1
ATE180479T1 AT94301871T AT94301871T ATE180479T1 AT E180479 T1 ATE180479 T1 AT E180479T1 AT 94301871 T AT94301871 T AT 94301871T AT 94301871 T AT94301871 T AT 94301871T AT E180479 T1 ATE180479 T1 AT E180479T1
Authority
AT
Austria
Prior art keywords
thiophenes
sulfonate
derivatives
carbamat
aroyl
Prior art date
Application number
AT94301871T
Other languages
English (en)
Inventor
Larry John Black
Henry Uhlman Bryant
George Joseph Cullinan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE180479T1 publication Critical patent/ATE180479T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94301871T 1993-03-19 1994-03-16 Sulfonat- und carbamatderivate von 3-aroyl- benzo(beta)thiophenen ATE180479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/035,121 US5482949A (en) 1993-03-19 1993-03-19 Sulfonate derivatives of 3-aroylbenzo[b]thiophenes

Publications (1)

Publication Number Publication Date
ATE180479T1 true ATE180479T1 (de) 1999-06-15

Family

ID=21880778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94301871T ATE180479T1 (de) 1993-03-19 1994-03-16 Sulfonat- und carbamatderivate von 3-aroyl- benzo(beta)thiophenen

Country Status (22)

Country Link
US (5) US5482949A (de)
EP (1) EP0617030B1 (de)
JP (1) JPH06321937A (de)
CN (1) CN1097420A (de)
AT (1) ATE180479T1 (de)
AU (1) AU670177B2 (de)
BR (1) BR9401183A (de)
CZ (1) CZ57894A3 (de)
DE (1) DE69418639T2 (de)
DK (1) DK0617030T3 (de)
ES (1) ES2132339T3 (de)
FI (1) FI941262A (de)
GR (1) GR3030317T3 (de)
HU (1) HUT70549A (de)
IL (1) IL108958A0 (de)
NO (1) NO940940L (de)
NZ (1) NZ260085A (de)
PH (1) PH30177A (de)
SI (1) SI0617030T1 (de)
TW (1) TW304953B (de)
YU (1) YU12794A (de)
ZA (1) ZA941786B (de)

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US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
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WO1996040098A2 (en) * 1995-06-07 1996-12-19 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
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US5441964A (en) * 1993-10-15 1995-08-15 Eli Lilly And Company Methods for inhibiting bone loss using substituted benzothiophene
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US6451817B1 (en) 1995-03-10 2002-09-17 Eli Lilly And Company Alpha-substituted-1-benzyl-napthyls
US5622974A (en) * 1995-03-10 1997-04-22 Eli Lilly And Company α-substituted-3-benzyl-benzofurans
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US5567828A (en) * 1995-06-07 1996-10-22 Eli Lilly And Company Compounds and compositions with nitrogen-containing non-basic side
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GB9523999D0 (en) 1995-11-23 1996-01-24 Lilly Co Eli Indolyl neuropeptide y receptor antagonists
US5726168A (en) * 1995-10-12 1998-03-10 Eli Lilly And Company Lipophilic benzothiophenes
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IL125863A (en) * 1996-02-22 2000-10-31 Lilly Co Eli Benzothiophenes and formulations containing same
IL120266A (en) * 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
US5688796A (en) * 1996-03-12 1997-11-18 Eli Lilly And Company Heterocyclic substituted benzothiophenes, compositions, and methods
IL126320A (en) * 1996-03-26 2001-08-08 Lilly Co Eli Reloxifen and pharmaceuticals containing it
US5843984A (en) * 1996-05-09 1998-12-01 Eli Lilly And Company Sulfated benzothiophene derivatives, methods of use and formulations containing same
PL330814A1 (en) 1996-06-20 1999-06-07 Regents Board Of Compounds for and methods of delivering pharmaceutical preparations and their application
CA2206752A1 (en) * 1996-07-02 1998-01-02 George Joseph Cullinan Benzothiophene compounds, intermediates, processes, and methods of use
CA2206997A1 (en) * 1996-07-10 1998-01-10 Eli Lilly And Company Benzothiophene compounds and methods of use
PE108598A1 (es) * 1996-08-28 1999-01-13 Lilly Co Eli Benzotiofenos amorfos, procedimientos de preparacion y procedimientos de uso
CA2214072C (en) * 1996-08-29 2006-11-14 Eli Lilly And Company Benzo [b] thiophene compounds, intermediates, processes, compositions, and methods
CA2213810C (en) * 1996-08-29 2006-06-06 Lewis Dale Pennington Benzo¬b|thiophene compounds, intermediates, processes, compositions and methods
CA2214922A1 (en) * 1996-09-27 1998-03-27 Eli Lilly And Company Benzothiophene compounds, compositions, and methods
US5948796A (en) * 1996-10-10 1999-09-07 Eli Lilly And Company Benzo B!thiophene compounds, intermediates, formulations, and methods
CA2217373A1 (en) * 1996-10-10 1998-04-10 Michael John Martin Benzo¬b|thiophene compounds, intermediates, formulations, and methods
CA2218756A1 (en) * 1996-10-25 1998-04-25 Kristin Sue Marron Substituted benzo¢b!thiophene compounds having activity as selective estrogen receptor modulators
WO1998046588A2 (en) * 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6025373A (en) * 1997-04-22 2000-02-15 Eli Lilly And Company Methods for reducing fibrinogen
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
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JP4665805B2 (ja) * 2006-03-17 2011-04-06 カシオ計算機株式会社 印字装置

Also Published As

Publication number Publication date
US5482949A (en) 1996-01-09
DE69418639T2 (de) 1999-10-07
HUT70549A (en) 1995-10-30
CN1097420A (zh) 1995-01-18
EP0617030A1 (de) 1994-09-28
AU5786394A (en) 1994-09-22
ZA941786B (en) 1995-09-14
FI941262A0 (fi) 1994-03-17
US5798351A (en) 1998-08-25
NO940940L (no) 1994-09-20
HU9400774D0 (en) 1994-06-28
GR3030317T3 (en) 1999-09-30
EP0617030B1 (de) 1999-05-26
TW304953B (de) 1997-05-11
ES2132339T3 (es) 1999-08-16
US5599833A (en) 1997-02-04
FI941262A (fi) 1994-09-20
YU12794A (sh) 1997-01-08
US5994371A (en) 1999-11-30
AU670177B2 (en) 1996-07-04
NO940940D0 (no) 1994-03-16
JPH06321937A (ja) 1994-11-22
IL108958A0 (en) 1994-06-24
US5605924A (en) 1997-02-25
SI0617030T1 (en) 1999-10-31
PH30177A (en) 1997-01-21
DK0617030T3 (da) 1999-11-08
BR9401183A (pt) 1994-11-01
NZ260085A (en) 1995-12-21
CZ57894A3 (en) 1994-12-15
DE69418639D1 (de) 1999-07-01

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