ATE171950T1 - Faktor vii-peptide - Google Patents

Faktor vii-peptide

Info

Publication number
ATE171950T1
ATE171950T1 AT94918437T AT94918437T ATE171950T1 AT E171950 T1 ATE171950 T1 AT E171950T1 AT 94918437 T AT94918437 T AT 94918437T AT 94918437 T AT94918437 T AT 94918437T AT E171950 T1 ATE171950 T1 AT E171950T1
Authority
AT
Austria
Prior art keywords
pct
date
sec
peptides
factor vii
Prior art date
Application number
AT94918437T
Other languages
English (en)
Inventor
Ross Wentworth Stephens
Lars Orning
Kjell Steinar Sakariassen
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939312601A external-priority patent/GB9312601D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Application granted granted Critical
Publication of ATE171950T1 publication Critical patent/ATE171950T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6437Coagulation factor VIIa (3.4.21.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21021Coagulation factor VIIa (3.4.21.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT94918437T 1993-06-18 1994-06-17 Faktor vii-peptide ATE171950T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939312601A GB9312601D0 (en) 1993-06-18 1993-06-18 Peptides
GB9409335A GB9409335D0 (en) 1993-06-18 1994-05-10 Peptides

Publications (1)

Publication Number Publication Date
ATE171950T1 true ATE171950T1 (de) 1998-10-15

Family

ID=26303086

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94918437T ATE171950T1 (de) 1993-06-18 1994-06-17 Faktor vii-peptide

Country Status (15)

Country Link
US (1) US5962418A (de)
EP (1) EP0703923B1 (de)
JP (1) JPH08511794A (de)
CN (1) CN1125450A (de)
AT (1) ATE171950T1 (de)
CA (1) CA2164422A1 (de)
CZ (1) CZ334095A3 (de)
DE (1) DE69413817T2 (de)
DK (1) DK0703923T3 (de)
FI (1) FI956055A (de)
HU (1) HUT74873A (de)
NO (1) NO955067L (de)
NZ (1) NZ267453A (de)
SK (1) SK156395A3 (de)
WO (1) WO1995000541A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
GB9425380D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
GB9425381D0 (en) * 1994-12-15 1995-02-15 Nycomed Pharma As Peptides
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
WO1999013063A1 (en) * 1997-09-09 1999-03-18 Nycomed Imaging As Factor vii fragments and analogs thereof and their use in the treatment of blood clottng disorders
WO1999013062A1 (en) * 1997-09-09 1999-03-18 Nycomed Imaging As Factors vii fragments and analogs thereof and their use in the treatment of blood clotting disorders
EP0987274A1 (de) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Faktor VIIa Inhibitore
WO2000077246A2 (en) * 1999-06-14 2000-12-21 Novo Nordisk A/S A METHOD FOR IDENTIFYING A DRUG CANDIDATE HAVING AN INHIBITORY ACTION ON FVII-TF ACTIVITY, AND FVIIa/TF ACTIVITY INHIBITING COMPOUNDS
IL147269A0 (en) 1999-07-02 2002-08-14 Genentech Inc FVIIa ANTAGONISTS
US7164002B2 (en) 2002-02-06 2007-01-16 Genentech, Inc. FVIIa antagonists
US20060257359A1 (en) * 2005-02-28 2006-11-16 Cedric Francois Modifying macrophage phenotype for treatment of disease
ES2856968T3 (es) 2016-01-15 2021-09-28 Rigshospitalet Adquisición de imágenes de TEP cuantitativas de la expresión de factor tisular usando factor VII inhibido en el punto activo y marcado con 18F
EP3541432A4 (de) 2016-11-17 2020-08-05 Minerva Imaging ApS 177-lu-markierter, durch aktive stelle inhibierter faktor vii

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496927A (en) * 1985-02-04 1996-03-05 Merrell Pharmaceuticals Inc. Peptidase inhibitors
CA1298033C (en) * 1985-04-16 1992-03-24 Takaharu Tanaka Dipeptide derivative of fatty acid
US5087564A (en) * 1985-06-20 1992-02-11 Monsanto Company Release of recombinant peptides from polypeptides using V8 endopeptidase
US5047401A (en) * 1985-09-09 1991-09-10 Board Of Regents, The University Of Texas System Use of dipeptide alkyl esters to treat GVHD
EP0391999A4 (en) * 1988-09-23 1991-03-13 Corvas, Inc. Peptidyl inhibitors of the initiation of coagulation
DE69131292T2 (de) * 1990-01-29 1999-09-30 Zymogenetics, Inc. Antikoagulierende proteine
DE4007902A1 (de) * 1990-03-13 1991-09-19 Behringwerke Ag Synthetische peptide, die sequenzen aus faktor viia enthalten und deren verwendung
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
WO1993009804A1 (en) * 1991-11-18 1993-05-27 The Scripps Research Institute Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation

Also Published As

Publication number Publication date
DE69413817D1 (de) 1998-11-12
AU691814B2 (en) 1998-05-28
CZ334095A3 (en) 1996-07-17
EP0703923B1 (de) 1998-10-07
FI956055A (fi) 1996-01-26
NO955067D0 (no) 1995-12-14
DE69413817T2 (de) 1999-06-10
JPH08511794A (ja) 1996-12-10
HUT74873A (en) 1997-02-28
AU6975594A (en) 1995-01-17
NZ267453A (en) 1997-03-24
HU9503593D0 (en) 1996-02-28
DK0703923T3 (da) 1999-06-21
WO1995000541A1 (en) 1995-01-05
EP0703923A1 (de) 1996-04-03
FI956055A0 (fi) 1995-12-15
US5962418A (en) 1999-10-05
SK156395A3 (en) 1996-06-05
CA2164422A1 (en) 1995-01-05
NO955067L (no) 1995-12-14
CN1125450A (zh) 1996-06-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee